BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1209 related articles for article (PubMed ID: 21152010)

  • 1. Identifying a high fraction of the human genome to be under selective constraint using GERP++.
    Davydov EV; Goode DL; Sirota M; Cooper GM; Sidow A; Batzoglou S
    PLoS Comput Biol; 2010 Dec; 6(12):e1001025. PubMed ID: 21152010
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distribution and intensity of constraint in mammalian genomic sequence.
    Cooper GM; Stone EA; Asimenos G; ; Green ED; Batzoglou S; Sidow A
    Genome Res; 2005 Jul; 15(7):901-13. PubMed ID: 15965027
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Population genetic models of GERP scores suggest pervasive turnover of constrained sites across mammalian evolution.
    Huber CD; Kim BY; Lohmueller KE
    PLoS Genet; 2020 May; 16(5):e1008827. PubMed ID: 32469868
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome.
    Margulies EH; Cooper GM; Asimenos G; Thomas DJ; Dewey CN; Siepel A; Birney E; Keefe D; Schwartz AS; Hou M; Taylor J; Nikolaev S; Montoya-Burgos JI; Löytynoja A; Whelan S; Pardi F; Massingham T; Brown JB; Bickel P; Holmes I; Mullikin JC; Ureta-Vidal A; Paten B; Stone EA; Rosenbloom KR; Kent WJ; Bouffard GG; Guan X; Hansen NF; Idol JR; Maduro VV; Maskeri B; McDowell JC; Park M; Thomas PJ; Young AC; Blakesley RW; Muzny DM; Sodergren E; Wheeler DA; Worley KC; Jiang H; Weinstock GM; Gibbs RA; Graves T; Fulton R; Mardis ER; Wilson RK; Clamp M; Cuff J; Gnerre S; Jaffe DB; Chang JL; Lindblad-Toh K; Lander ES; Hinrichs A; Trumbower H; Clawson H; Zweig A; Kuhn RM; Barber G; Harte R; Karolchik D; Field MA; Moore RA; Matthewson CA; Schein JE; Marra MA; Antonarakis SE; Batzoglou S; Goldman N; Hardison R; Haussler D; Miller W; Pachter L; Green ED; Sidow A
    Genome Res; 2007 Jun; 17(6):760-74. PubMed ID: 17567995
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A high-resolution map of human evolutionary constraint using 29 mammals.
    Lindblad-Toh K; Garber M; Zuk O; Lin MF; Parker BJ; Washietl S; Kheradpour P; Ernst J; Jordan G; Mauceli E; Ward LD; Lowe CB; Holloway AK; Clamp M; Gnerre S; Alföldi J; Beal K; Chang J; Clawson H; Cuff J; Di Palma F; Fitzgerald S; Flicek P; Guttman M; Hubisz MJ; Jaffe DB; Jungreis I; Kent WJ; Kostka D; Lara M; Martins AL; Massingham T; Moltke I; Raney BJ; Rasmussen MD; Robinson J; Stark A; Vilella AJ; Wen J; Xie X; Zody MC; ; Baldwin J; Bloom T; Chin CW; Heiman D; Nicol R; Nusbaum C; Young S; Wilkinson J; Worley KC; Kovar CL; Muzny DM; Gibbs RA; ; Cree A; Dihn HH; Fowler G; Jhangiani S; Joshi V; Lee S; Lewis LR; Nazareth LV; Okwuonu G; Santibanez J; Warren WC; Mardis ER; Weinstock GM; Wilson RK; ; Delehaunty K; Dooling D; Fronik C; Fulton L; Fulton B; Graves T; Minx P; Sodergren E; Birney E; Margulies EH; Herrero J; Green ED; Haussler D; Siepel A; Goldman N; Pollard KS; Pedersen JS; Lander ES; Kellis M
    Nature; 2011 Oct; 478(7370):476-82. PubMed ID: 21993624
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identifying novel constrained elements by exploiting biased substitution patterns.
    Garber M; Guttman M; Clamp M; Zody MC; Friedman N; Xie X
    Bioinformatics; 2009 Jun; 25(12):i54-62. PubMed ID: 19478016
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Detection of nonneutral substitution rates on mammalian phylogenies.
    Pollard KS; Hubisz MJ; Rosenbloom KR; Siepel A
    Genome Res; 2010 Jan; 20(1):110-21. PubMed ID: 19858363
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A genome alignment of 120 mammals highlights ultraconserved element variability and placenta-associated enhancers.
    Hecker N; Hiller M
    Gigascience; 2020 Jan; 9(1):. PubMed ID: 31899510
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Local conservation scores without a priori assumptions on neutral substitution rates.
    Dingel J; Hanus P; Leonardi N; Hagenauer J; Zech J; Mueller JC
    BMC Bioinformatics; 2008 Apr; 9():190. PubMed ID: 18405366
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ABC: software for interactive browsing of genomic multiple sequence alignment data.
    Cooper GM; Singaravelu SA; Sidow A
    BMC Bioinformatics; 2004 Dec; 5():192. PubMed ID: 15588288
    [TBL] [Abstract][Full Text] [Related]  

  • 11. VCFtoTree: a user-friendly tool to construct locus-specific alignments and phylogenies from thousands of anthropologically relevant genome sequences.
    Xu D; Jaber Y; Pavlidis P; Gokcumen O
    BMC Bioinformatics; 2017 Sep; 18(1):426. PubMed ID: 28950836
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bayesian coestimation of phylogeny and sequence alignment.
    Lunter G; Miklós I; Drummond A; Jensen JL; Hein J
    BMC Bioinformatics; 2005 Apr; 6():83. PubMed ID: 15804354
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MuSiC: a tool for multiple sequence alignment with constraints.
    Tsai YT; Huang YP; Yu CT; Lu CL
    Bioinformatics; 2004 Sep; 20(14):2309-11. PubMed ID: 15059840
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RepeatFiller newly identifies megabases of aligning repetitive sequences and improves annotations of conserved non-exonic elements.
    Osipova E; Hecker N; Hiller M
    Gigascience; 2019 Nov; 8(11):. PubMed ID: 31742600
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mulan: multiple-sequence local alignment and visualization for studying function and evolution.
    Ovcharenko I; Loots GG; Giardine BM; Hou M; Ma J; Hardison RC; Stubbs L; Miller W
    Genome Res; 2005 Jan; 15(1):184-94. PubMed ID: 15590941
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An initial strategy for the systematic identification of functional elements in the human genome by low-redundancy comparative sequencing.
    Margulies EH; Vinson JP; ; Miller W; Jaffe DB; Lindblad-Toh K; Chang JL; Green ED; Lander ES; Mullikin JC; Clamp M
    Proc Natl Acad Sci U S A; 2005 Mar; 102(13):4795-800. PubMed ID: 15778292
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences.
    King DC; Taylor J; Elnitski L; Chiaromonte F; Miller W; Hardison RC
    Genome Res; 2005 Aug; 15(8):1051-60. PubMed ID: 16024817
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Accurate anchoring alignment of divergent sequences.
    Huang W; Umbach DM; Li L
    Bioinformatics; 2006 Jan; 22(1):29-34. PubMed ID: 16301203
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Analysis of sequence conservation at nucleotide resolution.
    Asthana S; Roytberg M; Stamatoyannopoulos J; Sunyaev S
    PLoS Comput Biol; 2007 Dec; 3(12):e254. PubMed ID: 18166073
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Approaches to comparative sequence analysis: towards a functional view of vertebrate genomes.
    Margulies EH; Birney E
    Nat Rev Genet; 2008 Apr; 9(4):303-13. PubMed ID: 18347593
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 61.