383 related articles for article (PubMed ID: 21156028)
1. The role of DYRK1A in neurodegenerative diseases.
Wegiel J; Gong CX; Hwang YW
FEBS J; 2011 Jan; 278(2):236-45. PubMed ID: 21156028
[TBL] [Abstract][Full Text] [Related]
2. Link between DYRK1A overexpression and several-fold enhancement of neurofibrillary degeneration with 3-repeat tau protein in Down syndrome.
Wegiel J; Kaczmarski W; Barua M; Kuchna I; Nowicki K; Wang KC; Wegiel J; Yang SM; Frackowiak J; Mazur-Kolecka B; Silverman WP; Reisberg B; Monteiro I; de Leon M; Wisniewski T; Dalton A; Lai F; Hwang YW; Adayev T; Liu F; Iqbal K; Iqbal IG; Gong CX
J Neuropathol Exp Neurol; 2011 Jan; 70(1):36-50. PubMed ID: 21157379
[TBL] [Abstract][Full Text] [Related]
3. The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome.
Wegiel J; Dowjat K; Kaczmarski W; Kuchna I; Nowicki K; Frackowiak J; Mazur Kolecka B; Wegiel J; Silverman WP; Reisberg B; Deleon M; Wisniewski T; Gong CX; Liu F; Adayev T; Chen-Hwang MC; Hwang YW
Acta Neuropathol; 2008 Oct; 116(4):391-407. PubMed ID: 18696092
[TBL] [Abstract][Full Text] [Related]
4. Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes.
García-Cerro S; Rueda N; Vidal V; Lantigua S; Martínez-Cué C
Neurobiol Dis; 2017 Oct; 106():76-88. PubMed ID: 28647555
[TBL] [Abstract][Full Text] [Related]
5. Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome.
Shi J; Zhang T; Zhou C; Chohan MO; Gu X; Wegiel J; Zhou J; Hwang YW; Iqbal K; Grundke-Iqbal I; Gong CX; Liu F
J Biol Chem; 2008 Oct; 283(42):28660-9. PubMed ID: 18658135
[TBL] [Abstract][Full Text] [Related]
6. Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
Ryoo SR; Cho HJ; Lee HW; Jeong HK; Radnaabazar C; Kim YS; Kim MJ; Son MY; Seo H; Chung SH; Song WJ
J Neurochem; 2008 Mar; 104(5):1333-44. PubMed ID: 18005339
[TBL] [Abstract][Full Text] [Related]
7. Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome.
Liu F; Liang Z; Wegiel J; Hwang YW; Iqbal K; Grundke-Iqbal I; Ramakrishna N; Gong CX
FASEB J; 2008 Sep; 22(9):3224-33. PubMed ID: 18509201
[TBL] [Abstract][Full Text] [Related]
8. DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.
Ryoo SR; Jeong HK; Radnaabazar C; Yoo JJ; Cho HJ; Lee HW; Kim IS; Cheon YH; Ahn YS; Chung SH; Song WJ
J Biol Chem; 2007 Nov; 282(48):34850-7. PubMed ID: 17906291
[TBL] [Abstract][Full Text] [Related]
9. Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE.
Jin N; Yin X; Gu J; Zhang X; Shi J; Qian W; Ji Y; Cao M; Gu X; Ding F; Iqbal K; Gong CX; Liu F
J Biol Chem; 2015 Jun; 290(24):15219-37. PubMed ID: 25918155
[TBL] [Abstract][Full Text] [Related]
10. Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice.
Yin X; Jin N; Shi J; Zhang Y; Wu Y; Gong CX; Iqbal K; Liu F
Sci Rep; 2017 Apr; 7(1):619. PubMed ID: 28377597
[TBL] [Abstract][Full Text] [Related]
11. [Elucidating Pathogenic Mechanisms of Early-onset Alzheimer's Disease in Down Syndrome Patients].
Asai M; Kawakubo T; Mori R; Iwata N
Yakugaku Zasshi; 2017; 137(7):801-805. PubMed ID: 28674290
[TBL] [Abstract][Full Text] [Related]
12. Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models.
Ferrer I; Barrachina M; Puig B; Martínez de Lagrán M; Martí E; Avila J; Dierssen M
Neurobiol Dis; 2005 Nov; 20(2):392-400. PubMed ID: 16242644
[TBL] [Abstract][Full Text] [Related]
13. Dyrk1A-mediated phosphorylation of Presenilin 1: a functional link between Down syndrome and Alzheimer's disease.
Ryu YS; Park SY; Jung MS; Yoon SH; Kwen MY; Lee SY; Choi SH; Radnaabazar C; Kim MK; Kim H; Kim K; Song WJ; Chung SH
J Neurochem; 2010 Nov; 115(3):574-84. PubMed ID: 20456003
[TBL] [Abstract][Full Text] [Related]
14. DYRK1A antagonists rescue degeneration and behavioural deficits of in vivo models based on amyloid-β, Tau and DYRK1A neurotoxicity.
Zhu B; Parsons T; Foley C; Shaw Y; Dunckley T; Hulme C; Hodge JJL
Sci Rep; 2022 Sep; 12(1):15847. PubMed ID: 36151233
[TBL] [Abstract][Full Text] [Related]
15. A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.
Coutadeur S; Benyamine H; Delalonde L; de Oliveira C; Leblond B; Foucourt A; Besson T; Casagrande AS; Taverne T; Girard A; Pando MP; Désiré L
J Neurochem; 2015 May; 133(3):440-51. PubMed ID: 25556849
[TBL] [Abstract][Full Text] [Related]
16. Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations.
Toiber D; Azkona G; Ben-Ari S; Torán N; Soreq H; Dierssen M
Neurobiol Dis; 2010 Oct; 40(1):348-59. PubMed ID: 20600907
[TBL] [Abstract][Full Text] [Related]
17. Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusion.
Yin X; Jin N; Gu J; Shi J; Zhou J; Gong CX; Iqbal K; Grundke-Iqbal I; Liu F
J Biol Chem; 2012 Aug; 287(36):30497-506. PubMed ID: 22767602
[TBL] [Abstract][Full Text] [Related]
18. Identification of selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors and their effects on tau and microtubule.
Wu YW; HuangFu WC; Lin TE; Peng CH; Tu HJ; Sung TY; Sung TY; Yen SC; Pan SL; Hsu KC
Int J Biol Macromol; 2024 Feb; 259(Pt 1):129074. PubMed ID: 38163507
[TBL] [Abstract][Full Text] [Related]
19. Neprilysin Is Suppressed by Dual-Specificity Tyrosine-Phosphorylation Regulated Kinase 1A (DYRK1A) in Down-Syndrome-Derived Fibroblasts.
Kawakubo T; Mori R; Shirotani K; Iwata N; Asai M
Biol Pharm Bull; 2017; 40(3):327-333. PubMed ID: 28250274
[TBL] [Abstract][Full Text] [Related]
20. Function and regulation of Dyrk1A: towards understanding Down syndrome.
Park J; Song WJ; Chung KC
Cell Mol Life Sci; 2009 Oct; 66(20):3235-40. PubMed ID: 19685005
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
