These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

320 related articles for article (PubMed ID: 21157379)

  • 1. Link between DYRK1A overexpression and several-fold enhancement of neurofibrillary degeneration with 3-repeat tau protein in Down syndrome.
    Wegiel J; Kaczmarski W; Barua M; Kuchna I; Nowicki K; Wang KC; Wegiel J; Yang SM; Frackowiak J; Mazur-Kolecka B; Silverman WP; Reisberg B; Monteiro I; de Leon M; Wisniewski T; Dalton A; Lai F; Hwang YW; Adayev T; Liu F; Iqbal K; Iqbal IG; Gong CX
    J Neuropathol Exp Neurol; 2011 Jan; 70(1):36-50. PubMed ID: 21157379
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome.
    Wegiel J; Dowjat K; Kaczmarski W; Kuchna I; Nowicki K; Frackowiak J; Mazur Kolecka B; Wegiel J; Silverman WP; Reisberg B; Deleon M; Wisniewski T; Gong CX; Liu F; Adayev T; Chen-Hwang MC; Hwang YW
    Acta Neuropathol; 2008 Oct; 116(4):391-407. PubMed ID: 18696092
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome.
    Liu F; Liang Z; Wegiel J; Hwang YW; Iqbal K; Grundke-Iqbal I; Ramakrishna N; Gong CX
    FASEB J; 2008 Sep; 22(9):3224-33. PubMed ID: 18509201
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes.
    García-Cerro S; Rueda N; Vidal V; Lantigua S; Martínez-Cué C
    Neurobiol Dis; 2017 Oct; 106():76-88. PubMed ID: 28647555
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusion.
    Yin X; Jin N; Gu J; Shi J; Zhou J; Gong CX; Iqbal K; Grundke-Iqbal I; Liu F
    J Biol Chem; 2012 Aug; 287(36):30497-506. PubMed ID: 22767602
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation.
    Lee YH; Im E; Hyun M; Park J; Chung KC
    J Biol Chem; 2021; 296():100245. PubMed ID: 33380426
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice.
    Yin X; Jin N; Shi J; Zhang Y; Wu Y; Gong CX; Iqbal K; Liu F
    Sci Rep; 2017 Apr; 7(1):619. PubMed ID: 28377597
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.
    Ryoo SR; Jeong HK; Radnaabazar C; Yoo JJ; Cho HJ; Lee HW; Kim IS; Cheon YH; Ahn YS; Chung SH; Song WJ
    J Biol Chem; 2007 Nov; 282(48):34850-7. PubMed ID: 17906291
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models.
    Ferrer I; Barrachina M; Puig B; Martínez de Lagrán M; Martí E; Avila J; Dierssen M
    Neurobiol Dis; 2005 Nov; 20(2):392-400. PubMed ID: 16242644
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome.
    Shi J; Zhang T; Zhou C; Chohan MO; Gu X; Wegiel J; Zhou J; Hwang YW; Iqbal K; Grundke-Iqbal I; Gong CX; Liu F
    J Biol Chem; 2008 Oct; 283(42):28660-9. PubMed ID: 18658135
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of DYRK1A in neurodegenerative diseases.
    Wegiel J; Gong CX; Hwang YW
    FEBS J; 2011 Jan; 278(2):236-45. PubMed ID: 21156028
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE.
    Jin N; Yin X; Gu J; Zhang X; Shi J; Qian W; Ji Y; Cao M; Gu X; Ding F; Iqbal K; Gong CX; Liu F
    J Biol Chem; 2015 Jun; 290(24):15219-37. PubMed ID: 25918155
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Elucidating Pathogenic Mechanisms of Early-onset Alzheimer's Disease in Down Syndrome Patients].
    Asai M; Kawakubo T; Mori R; Iwata N
    Yakugaku Zasshi; 2017; 137(7):801-805. PubMed ID: 28674290
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of alternative splicing of tau exon 10 by 9G8 and Dyrk1A.
    Ding S; Shi J; Qian W; Iqbal K; Grundke-Iqbal I; Gong CX; Liu F
    Neurobiol Aging; 2012 Jul; 33(7):1389-99. PubMed ID: 21215488
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.
    Coutadeur S; Benyamine H; Delalonde L; de Oliveira C; Leblond B; Foucourt A; Besson T; Casagrande AS; Taverne T; Girard A; Pando MP; Désiré L
    J Neurochem; 2015 May; 133(3):440-51. PubMed ID: 25556849
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations.
    Toiber D; Azkona G; Ben-Ari S; Torán N; Soreq H; Dierssen M
    Neurobiol Dis; 2010 Oct; 40(1):348-59. PubMed ID: 20600907
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gene dosage-dependent association of DYRK1A with the cytoskeleton in the brain and lymphocytes of down syndrome patients.
    Dowjat K; Adayev T; Kaczmarski W; Wegiel J; Hwang YW
    J Neuropathol Exp Neurol; 2012 Dec; 71(12):1100-12. PubMed ID: 23147510
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HIV-1-Tat Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A Kinase.
    Kadri F; Pacifici M; Wilk A; Parker-Struckhoff A; Del Valle L; Hauser KF; Knapp PE; Parsons C; Jeansonne D; Lassak A; Peruzzi F
    J Biol Chem; 2015 Dec; 290(52):30931-46. PubMed ID: 26534959
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Involvement of the dual-specificity tyrosine phosphorylation-regulated kinase 1A-alternative splicing factor-calcium/calmodulin-dependent protein kinase IIδ signaling pathway in myocardial infarction-induced heart failure of rats.
    He J; Yao J; Sheng H; Zhu J
    J Card Fail; 2015 Sep; 21(9):751-60. PubMed ID: 26067684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
    Ryoo SR; Cho HJ; Lee HW; Jeong HK; Radnaabazar C; Kim YS; Kim MJ; Son MY; Seo H; Chung SH; Song WJ
    J Neurochem; 2008 Mar; 104(5):1333-44. PubMed ID: 18005339
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.