BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

103 related articles for article (PubMed ID: 21159507)

  • 1. Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT(7) antagonists.
    Rudolph DA; Dvorak CA; Dvorak L; Nepomuceno D; Bonaventure P; Lovenberg TW; Carruthers NI
    Bioorg Med Chem Lett; 2011 Jan; 21(1):42-4. PubMed ID: 21159507
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Indole-3-piperazinyl derivatives: novel chemical class of 5-HT(6) receptor antagonists.
    Nirogi RV; Deshpande AD; Kambhampati R; Badange RK; Kota L; Daulatabad AV; Shinde AK; Ahmad I; Kandikere V; Jayarajan P; Dubey PK
    Bioorg Med Chem Lett; 2011 Jan; 21(1):346-9. PubMed ID: 21134749
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.
    Campiani G; Butini S; Fattorusso C; Catalanotti B; Gemma S; Nacci V; Morelli E; Cagnotto A; Mereghetti I; Mennini T; Carli M; Minetti P; Di Cesare MA; Mastroianni D; Scafetta N; Galletti B; Stasi MA; Castorina M; Pacifici L; Vertechy M; Di Serio S; Ghirardi O; Tinti O; Carminati P
    J Med Chem; 2004 Jan; 47(1):143-57. PubMed ID: 14695828
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and pharmacological evaluation of aryl aminosulfonamide derivatives as potent 5-HT(6) receptor antagonists.
    Nirogi RV; Daulatabad AV; Parandhama G; Mohammad S; Sastri KR; Shinde AK; Dubey PK
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4440-3. PubMed ID: 20594839
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and serotonergic activity of substituted 2, N-benzylcarboxamido-5-(2-ethyl-1-dioxoimidazolidinyl)-N, N-dimethyltryptamine derivatives: novel antagonists for the vascular 5-HT(1B)-like receptor.
    Moloney GP; Martin GR; Mathews N; Milne A; Hobbs H; Dodsworth S; Sang PY; Knight C; Williams M; Maxwell M; Glen RC
    J Med Chem; 1999 Jul; 42(14):2504-26. PubMed ID: 10411472
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.
    Hirokawa Y; Fujiwara I; Suzuki K; Harada H; Yoshikawa T; Yoshida N; Kato S
    J Med Chem; 2003 Feb; 46(5):702-15. PubMed ID: 12593651
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with selective affinity for the 5-HT(4) receptor: synthesis and structure-affinity and structure-activity relationships of a new series of partial agonist and antagonist derivatives.
    Tapia I; Alonso-Cires L; López-Tudanca PL; Mosquera R; Labeaga L; Innerárity A; Orjales A
    J Med Chem; 1999 Jul; 42(15):2870-80. PubMed ID: 10425096
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pyrroloquinoxaline derivatives as high-affinity and selective 5-HT(3) receptor agonists: synthesis, further structure-activity relationships, and biological studies.
    Campiani G; Morelli E; Gemma S; Nacci V; Butini S; Hamon M; Novellino E; Greco G; Cagnotto A; Goegan M; Cervo L; Dalla Valle F; Fracasso C; Caccia S; Mennini T
    J Med Chem; 1999 Oct; 42(21):4362-79. PubMed ID: 10543880
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel 1-(azacyclyl)-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines as 5-HT6 agonists and antagonists.
    Elokdah H; Li D; McFarlane G; Bernotas RC; Robichaud AJ; Magolda RL; Zhang GM; Smith D; Schechter LE
    Bioorg Med Chem; 2007 Sep; 15(18):6208-26. PubMed ID: 17624788
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N,N-Dimethyl-[9-(arylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl]amines as novel, potent and selective 5-HT₆ receptor antagonists.
    Nirogi RV; Konda JB; Kambhampati R; Shinde A; Bandyala TR; Gudla P; Kandukuri KK; Jayarajan P; Kandikere V; Dubey PK
    Bioorg Med Chem Lett; 2012 Nov; 22(22):6980-5. PubMed ID: 23036955
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 5-Cyclic amine-3-arylsulfonylindazoles as novel 5-HT6 receptor antagonists.
    Haydar SN; Yun H; Andrae PM; Mattes J; Zhang J; Kramer A; Smith DL; Huselton C; Graf R; Aschmies S; Schechter LE; Comery TA; Robichaud AJ
    J Med Chem; 2010 Mar; 53(6):2521-7. PubMed ID: 20170099
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sulfonamides with the N-alkyl-N'-dialkylguanidine moiety as 5-HT7 receptor ligands.
    Zajdel P; Subra G; Verdie P; Gabzdyl E; Bojarski AJ; Duszyńska B; Martinez J; Pawłowski M
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4827-31. PubMed ID: 19560916
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 3-(Arylsulfonyl)-1-(azacyclyl)-1H-indoles are 5-HT(6) receptor modulators.
    Bernotas RC; Antane S; Shenoy R; Le VD; Chen P; Harrison BL; Robichaud AJ; Zhang GM; Smith D; Schechter LE
    Bioorg Med Chem Lett; 2010 Mar; 20(5):1657-60. PubMed ID: 20138763
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Leopoldo M; Berardi F; Colabufo NA; Contino M; Lacivita E; Niso M; Perrone R; Tortorella V
    J Med Chem; 2004 Dec; 47(26):6616-24. PubMed ID: 15588097
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Benzimidazole derivatives as new serotonin 5-HT6 receptor antagonists. Molecular mechanisms of receptor inactivation.
    de la Fuente T; Martín-Fontecha M; Sallander J; Benhamú B; Campillo M; Medina RA; Pellissier LP; Claeysen S; Dumuis A; Pardo L; López-Rodríguez ML
    J Med Chem; 2010 Feb; 53(3):1357-69. PubMed ID: 20078106
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and structure-activity relationship of 2-(aminoalkyl)-2,3,3a,8-tetrahydrodibenzo[c,f]isoxazolo[2,3-a]azepine derivatives: a novel series of 5-HT(2A/2C) receptor antagonists. Part 2.
    Andrés JI; Alcázar J; Alonso JM; Díaz A; Fernández J; Gil P; Iturrino L; Matesanz E; Meert TF; Megens A; Sipido VK
    Bioorg Med Chem Lett; 2002 Jan; 12(2):249-53. PubMed ID: 11755365
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cycloalkanecarboxylic esters derived from lysergol, dihydrolysergol-I, and elymoclavine as partial agonists and antagonists at rat 5-HT2A receptors: pharmacological evidence that the indolo[4,3-fg]quinoline system of the ergolines is responsible for high 5-HT2A receptor affinity.
    Pertz HH; Milhahn H; Eich E
    J Med Chem; 1999 Feb; 42(4):659-68. PubMed ID: 10052973
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New antipsychotic agents with serotonin and dopamine antagonist properties based on a pyrrolo[2,1-b][1,3]benzothiazepine structure.
    Campiani G; Nacci V; Bechelli S; Ciani SM; Garofalo A; Fiorini I; Wikström H; de Boer P; Liao Y; Tepper PG; Cagnotto A; Mennini T
    J Med Chem; 1998 Sep; 41(20):3763-72. PubMed ID: 9748351
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 4-Aminoethylpiperazinyl aryl ketones with 5-HT₁A/5-HT₇ selectivity.
    Kim MK; Lee HS; Kim S; Cho SY; Roth BL; Chong Y; Choo H
    Bioorg Med Chem; 2012 Jan; 20(2):1139-48. PubMed ID: 22196512
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and structure-activity relationship (SAR) of (5,7-disubstituted 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidin-2-yl)-methylamines as potent serotonin 5-HT(6) receptor (5-HT(6)R) antagonists.
    Ivachtchenko AV; Golovina ES; Kadieva MG; Kysil VM; Mitkin OD; Tkachenko SE; Okun IM
    J Med Chem; 2011 Dec; 54(23):8161-73. PubMed ID: 22029285
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.