BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

382 related articles for article (PubMed ID: 2116173)

  • 1. Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
    Koga T; Shimada Y; Kuroda M; Tsujita Y; Hasegawa K; Yamazaki M
    Biochim Biophys Acta; 1990 Jul; 1045(2):115-20. PubMed ID: 2116173
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tissue-selective acute effects of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase on cholesterol biosynthesis in lens.
    Mosley ST; Kalinowski SS; Schafer BL; Tanaka RD
    J Lipid Res; 1989 Sep; 30(9):1411-20. PubMed ID: 2513368
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective inhibition of cholesterol synthesis in liver versus extrahepatic tissues by HMG-CoA reductase inhibitors.
    Parker RA; Clark RW; Sit SY; Lanier TL; Grosso RA; Wright JJ
    J Lipid Res; 1990 Jul; 31(7):1271-82. PubMed ID: 2401858
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of cholesterol synthesis ex vivo and in vivo by fluvastatin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
    Yamamoto A; Itoh S; Hoshi K; Ichihara K
    Experientia; 1995 Mar; 51(3):223-6. PubMed ID: 7698284
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of long-term administration of HMG-CoA reductase inhibitors on cholesterol synthesis in lens.
    Kalinowski SS; Tanaka RD; Mosley ST
    Exp Eye Res; 1991 Aug; 53(2):179-86. PubMed ID: 1915674
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tissue-selective inhibition of sterol synthesis in mice by pravastatin sodium after a single or repeated oral administrations.
    Koga T; Kikuchi T; Miyazaki A; Koike H
    Lipids; 1995 Aug; 30(8):775-9. PubMed ID: 7475995
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tissue selectivity of pravastatin sodium, lovastatin and simvastatin. The relationship between inhibition of de novo sterol synthesis and active drug concentrations in the liver, spleen and testis in rat.
    Koga T; Fukuda K; Shimada Y; Fukami M; Koike H; Tsujita Y
    Eur J Biochem; 1992 Oct; 209(1):315-9. PubMed ID: 1396707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro myotoxicity of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, pravastatin, lovastatin, and simvastatin, using neonatal rat skeletal myocytes.
    Masters BA; Palmoski MJ; Flint OP; Gregg RE; Wang-Iverson D; Durham SK
    Toxicol Appl Pharmacol; 1995 Mar; 131(1):163-74. PubMed ID: 7878672
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of rat brain prostaglandin D synthase by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.
    Islam F; Watanabe Y; Hayaishi O
    Biochem Int; 1990 Nov; 22(4):601-5. PubMed ID: 2127671
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tissue selectivity of the cholesterol-lowering agents lovastatin, simvastatin and pravastatin in rats in vivo.
    Germershausen JI; Hunt VM; Bostedor RG; Bailey PJ; Karkas JD; Alberts AW
    Biochem Biophys Res Commun; 1989 Feb; 158(3):667-75. PubMed ID: 2493245
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypercholesterolaemia: simvastatin and pravastatin alter cholesterol metabolism by different mechanisms.
    Owens D; Collins P; Johnson A; Tighe O; Robinson K; Tomkin GH
    Biochim Biophys Acta; 1991 Apr; 1082(3):303-9. PubMed ID: 1903069
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cholesterol content of the rat lens is lowered by administration of simvastatin, but not by pravastatin.
    De Vries AC; Vermeer MA; Bredman JJ; Bär PR; Cohen LH
    Exp Eye Res; 1993 Apr; 56(4):393-9. PubMed ID: 8500554
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of cholesterol synthesis and hepatic 3-hydroxy-3-methylglutaryl--CoA reductase in rats by simvastatin and pravastatin.
    Del Puppo M; Rauli S; Galli Kienle M
    Lipids; 1995 Nov; 30(11):1057-61. PubMed ID: 8569435
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pravastatin inhibited the cholesterol synthesis in human hepatoma cell line Hep G2 less than simvastatin and lovastatin, which is reflected in the upregulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and squalene synthase.
    Cohen LH; van Vliet A; Roodenburg L; Jansen LM; Griffioen M
    Biochem Pharmacol; 1993 Jun; 45(11):2203-8. PubMed ID: 8517861
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pravastatin and simvastatin differently inhibit cholesterol biosynthesis in human lens.
    de Vries AC; Vermeer MA; Bloemendal H; Cohen LH
    Invest Ophthalmol Vis Sci; 1993 Feb; 34(2):377-84. PubMed ID: 8440592
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological profile of a novel synthetic inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Aoki T; Nishimura H; Nakagawa S; Kojima J; Suzuki H; Tamaki T; Wada Y; Yokoo N; Sato F; Kimata H; Kitahara M; Toyoda K; Sakashita M; Saito Y
    Arzneimittelforschung; 1997 Aug; 47(8):904-9. PubMed ID: 9296275
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Influence of pravastatin, a specific inhibitor of HMG-CoA reductase, on hepatic metabolism of cholesterol.
    Reihnér E; Rudling M; Ståhlberg D; Berglund L; Ewerth S; Björkhem I; Einarsson K; Angelin B
    N Engl J Med; 1990 Jul; 323(4):224-8. PubMed ID: 2114543
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Relative lipophilicities, solubilities, and structure-pharmacological considerations of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors pravastatin, lovastatin, mevastatin, and simvastatin.
    Serajuddin AT; Ranadive SA; Mahoney EM
    J Pharm Sci; 1991 Sep; 80(9):830-4. PubMed ID: 1800703
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacology and mechanism of action of the new HMG-CoA reductase inhibitors.
    Sirtori CR
    Pharmacol Res; 1990; 22(5):555-63. PubMed ID: 2126139
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Simvastatin but not pravastatin inhibits the proliferation of rat aorta myocytes.
    Corsini A; Raiteri M; Soma M; Fumagalli R; Paoletti R
    Pharmacol Res; 1991 Feb; 23(2):173-80. PubMed ID: 1905808
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.