383 related articles for article (PubMed ID: 2116173)
21. Purification and characterization of cytochrome P-450sca from Streptomyces carbophilus. ML-236B (compactin) induces a cytochrome P-450sca in Streptomyces carbophilus that hydroxylates ML-236B to pravastatin sodium (CS-514), a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase.
Matsuoka T; Miyakoshi S; Tanzawa K; Nakahara K; Hosobuchi M; Serizawa N
Eur J Biochem; 1989 Oct; 184(3):707-13. PubMed ID: 2509201
[TBL] [Abstract][Full Text] [Related]
22. Hepatic and nonhepatic sterol synthesis and tissue distribution following administration of a liver selective HMG-CoA reductase inhibitor, CI-981: comparison with selected HMG-CoA reductase inhibitors.
Bocan TM; Ferguson E; McNally W; Uhlendorf PD; Bak Mueller S; Dehart P; Sliskovic DR; Roth BD; Krause BR; Newton RS
Biochim Biophys Acta; 1992 Jan; 1123(2):133-44. PubMed ID: 1739744
[TBL] [Abstract][Full Text] [Related]
23. Action of lovastatin, simvastatin, and pravastatin on sterol synthesis and their antiproliferative effect in cultured myoblasts from human striated muscle.
van Vliet AK; Nègre-Aminou P; van Thiel GC; Bolhuis PA; Cohen LH
Biochem Pharmacol; 1996 Nov; 52(9):1387-92. PubMed ID: 8937448
[TBL] [Abstract][Full Text] [Related]
24. Effects of different inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, pravastatin sodium and simvastatin, on sterol synthesis and immunological functions in human lymphocytes in vitro.
Kurakata S; Kada M; Shimada Y; Komai T; Nomoto K
Immunopharmacology; 1996 Aug; 34(1):51-61. PubMed ID: 8880225
[TBL] [Abstract][Full Text] [Related]
25. Subcutaneous administration of HMG-CoA reductase inhibitors in hyperlipidaemic and normal rats.
Joles J; Willekes-Koolschijn N; Koomans H; Van Tol A; Geelhoed-Mieras T; Crommelin D; Van Bloois L; Krajnc-Franken M; Cohen L; Griffioen M
Lab Anim; 1992 Oct; 26(4):269-80. PubMed ID: 1447905
[TBL] [Abstract][Full Text] [Related]
26. Effect of a new synthetic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor on cholesterol synthesis and low density lipoprotein uptake by primary cultures of rat hepatocytes.
Saito Y; Shiki Y; Shirai K; Yoshida S
Arzneimittelforschung; 1988 Feb; 38(2):251-3. PubMed ID: 3130840
[TBL] [Abstract][Full Text] [Related]
27. The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in dogs.
Davis HR; Pula KK; Alton KB; Burrier RE; Watkins RW
Metabolism; 2001 Oct; 50(10):1234-41. PubMed ID: 11586500
[TBL] [Abstract][Full Text] [Related]
28. Lowering of plasma cholesterol levels in animals by lovastatin and simvastatin.
Chao Y; Chen JS; Hunt VM; Kuron GW; Karkas JD; Liou R; Alberts AW
Eur J Clin Pharmacol; 1991; 40 Suppl 1():S11-4. PubMed ID: 2044637
[TBL] [Abstract][Full Text] [Related]
29. Effects of simvastatin, a cholesterol synthesis inhibitor, on phosphatidylcholine synthesis in HepG2 cells.
Yanagita T; Yamamoto K; Ishida S; Sonda K; Morito F; Saku K; Sakai T
Clin Ther; 1994; 16(2):200-8. PubMed ID: 8062316
[TBL] [Abstract][Full Text] [Related]
30. Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences.
Lennernäs H; Fager G
Clin Pharmacokinet; 1997 May; 32(5):403-25. PubMed ID: 9160173
[TBL] [Abstract][Full Text] [Related]
31. Effect of simvastatin (MK-733) on the regulation of cholesterol synthesis in Hep G2 cells.
Nagata Y; Hidaka Y; Ishida F; Kamei T
Biochem Pharmacol; 1990 Aug; 40(4):843-50. PubMed ID: 2167097
[TBL] [Abstract][Full Text] [Related]
32. Different effects of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors on sterol synthesis in various human cell types.
van Vliet AK; van Thiel GC; Huisman RH; Moshage H; Yap SH; Cohen LH
Biochim Biophys Acta; 1995 Jan; 1254(1):105-11. PubMed ID: 7811739
[TBL] [Abstract][Full Text] [Related]
33. Regulation of HMG-CoA reductase, apoprotein-B and LDL receptor gene expression by the hypocholesterolemic drugs simvastatin and ciprofibrate in Hep G2, human and rat hepatocytes.
Qin W; Infante J; Wang SR; Infante R
Biochim Biophys Acta; 1992 Jul; 1127(1):57-66. PubMed ID: 1627634
[TBL] [Abstract][Full Text] [Related]
34. A two component-type cytochrome P-450 monooxygenase system in a prokaryote that catalyzes hydroxylation of ML-236B to pravastatin, a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Serizawa N; Matsuoka T
Biochim Biophys Acta; 1991 Jun; 1084(1):35-40. PubMed ID: 1905157
[TBL] [Abstract][Full Text] [Related]
35. Inhibition of cholesterol synthesis in vitro and in vivo by ML-236A and ML-236B, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Endo A; Tsujita Y; Kuroda M; Tanzawa K
Eur J Biochem; 1977 Jul; 77(1):31-6. PubMed ID: 908337
[No Abstract] [Full Text] [Related]
36. Transport mechanism of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors at the blood-brain barrier.
Tsuji A; Saheki A; Tamai I; Terasaki T
J Pharmacol Exp Ther; 1993 Dec; 267(3):1085-90. PubMed ID: 8263769
[TBL] [Abstract][Full Text] [Related]
37. Vastatins have a distinct effect on sterol synthesis and progesterone secretion in human granulosa cells in vitro.
van Vliet AK; van Thiel GC; Naaktgeboren N; Cohen LH
Biochim Biophys Acta; 1996 Jun; 1301(3):237-41. PubMed ID: 8664334
[TBL] [Abstract][Full Text] [Related]
38. Inhibition of proliferation of human smooth muscle cells by various HMG-CoA reductase inhibitors; comparison with other human cell types.
Nègre-Aminou P; van Vliet AK; van Erck M; van Thiel GC; van Leeuwen RE; Cohen LH
Biochim Biophys Acta; 1997 Apr; 1345(3):259-68. PubMed ID: 9150246
[TBL] [Abstract][Full Text] [Related]
39. Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in human hepatoma cell line Hep G2. Effects of inhibitors of cholesterol synthesis on enzyme activity.
Boogaard A; Griffioen M; Cohen LH
Biochem J; 1987 Jan; 241(2):345-51. PubMed ID: 3036060
[TBL] [Abstract][Full Text] [Related]
40. Generalized eczematous skin rash possibly due to HMG-CoA reductase inhibitors.
Krasovec M; Elsner P; Burg G
Dermatology; 1993; 186(4):248-52. PubMed ID: 8513188
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
