123 related articles for article (PubMed ID: 21168333)
1. Structure of rat aldose reductase-like protein AKR1B14 holoenzyme: Probing the role of His269 in coenzyme binding by site-directed mutagenesis.
Sundaram K; Dhagat U; Endo S; Chung R; Matsunaga T; Hara A; El-Kabbani O
Bioorg Med Chem Lett; 2011 Jan; 21(2):801-4. PubMed ID: 21168333
[TBL] [Abstract][Full Text] [Related]
2. Activation of aldo-keto reductase family member 1B14 (AKR1B14) by bile acids: Activation mechanism and bile acid-binding site.
Endo S; Matsunaga T; Fujita A; Kuragano T; Soda M; Sundaram K; Dhagat U; Tajima K; El-Kabbani O; Hara A
Biochimie; 2011 Sep; 93(9):1476-86. PubMed ID: 21586312
[TBL] [Abstract][Full Text] [Related]
3. Structure of the His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPH.
Sundaram K; Endo S; Matsunaga T; Tanaka N; Hara A; El-Kabbani O
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 Apr; 68(Pt 4):400-3. PubMed ID: 22505406
[TBL] [Abstract][Full Text] [Related]
4. Aldose and aldehyde reductases: structure-function studies on the coenzyme and inhibitor-binding sites.
El-Kabbani O; Old SE; Ginell SL; Carper DA
Mol Vis; 1999 Sep; 5():20. PubMed ID: 10493777
[TBL] [Abstract][Full Text] [Related]
5. Structure of human aldose reductase holoenzyme in complex with statil: an approach to structure-based inhibitor design of the enzyme.
El-Kabbani O; Ramsland P; Darmanin C; Chung RP; Podjarny A
Proteins; 2003 Feb; 50(2):230-8. PubMed ID: 12486717
[TBL] [Abstract][Full Text] [Related]
6. Crystal structure of human L-xylulose reductase holoenzyme: probing the role of Asn107 with site-directed mutagenesis.
El-Kabbani O; Ishikura S; Darmanin C; Carbone V; Chung RP; Usami N; Hara A
Proteins; 2004 May; 55(3):724-32. PubMed ID: 15103634
[TBL] [Abstract][Full Text] [Related]
7. Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors.
El-Kabbani O; Darmanin C; Schneider TR; Hazemann I; Ruiz F; Oka M; Joachimiak A; Schulze-Briese C; Tomizaki T; Mitschler A; Podjarny A
Proteins; 2004 Jun; 55(4):805-13. PubMed ID: 15146479
[TBL] [Abstract][Full Text] [Related]
8. Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity.
El-Kabbani O; Carbone V; Darmanin C; Oka M; Mitschler A; Podjarny A; Schulze-Briese C; Chung RP
J Med Chem; 2005 Aug; 48(17):5536-42. PubMed ID: 16107153
[TBL] [Abstract][Full Text] [Related]
9. Novel NADPH-binding domain revealed by the crystal structure of aldose reductase.
Rondeau JM; Tête-Favier F; Podjarny A; Reymann JM; Barth P; Biellmann JF; Moras D
Nature; 1992 Jan; 355(6359):469-72. PubMed ID: 1734286
[TBL] [Abstract][Full Text] [Related]
10. Structure of porcine aldehyde reductase holoenzyme.
el-Kabbani O; Judge K; Ginell SL; Myles DA; DeLucas LJ; Flynn TG
Nat Struct Biol; 1995 Aug; 2(8):687-92. PubMed ID: 7552731
[TBL] [Abstract][Full Text] [Related]
11. Structure of a glutathione conjugate bound to the active site of aldose reductase.
Singh R; White MA; Ramana KV; Petrash JM; Watowich SJ; Bhatnagar A; Srivastava SK
Proteins; 2006 Jul; 64(1):101-10. PubMed ID: 16639747
[TBL] [Abstract][Full Text] [Related]
12. Probing flexibility and "induced-fit" phenomena in aldose reductase by comparative crystal structure analysis and molecular dynamics simulations.
Sotriffer CA; Krämer O; Klebe G
Proteins; 2004 Jul; 56(1):52-66. PubMed ID: 15162486
[TBL] [Abstract][Full Text] [Related]
13. The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant.
Harrison DH; Bohren KM; Petsko GA; Ringe D; Gabbay KH
Biochemistry; 1997 Dec; 36(51):16134-40. PubMed ID: 9405046
[TBL] [Abstract][Full Text] [Related]
14. Probing the catalytic mechanism of GDP-4-keto-6-deoxy-d-mannose Epimerase/Reductase by kinetic and crystallographic characterization of site-specific mutants.
Rosano C; Bisso A; Izzo G; Tonetti M; Sturla L; De Flora A; Bolognesi M
J Mol Biol; 2000 Oct; 303(1):77-91. PubMed ID: 11021971
[TBL] [Abstract][Full Text] [Related]
15. Structural and biochemical investigations of the catalytic mechanism of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans.
Cobessi D; Tête-Favier F; Marchal S; Branlant G; Aubry A
J Mol Biol; 2000 Jun; 300(1):141-52. PubMed ID: 10864505
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure of NADP(H)-dependent 1,5-anhydro-D-fructose reductase from Sinorhizobium morelense at 2.2 A resolution: construction of a NADH-accepting mutant and its application in rare sugar synthesis.
Dambe TR; Kühn AM; Brossette T; Giffhorn F; Scheidig AJ
Biochemistry; 2006 Aug; 45(33):10030-42. PubMed ID: 16906761
[TBL] [Abstract][Full Text] [Related]
17. Aldehyde reductase: the role of C-terminal residues in defining substrate and cofactor specificities.
Rees-Milton KJ; Jia Z; Green NC; Bhatia M; El-Kabbani O; Flynn TG
Arch Biochem Biophys; 1998 Jul; 355(2):137-44. PubMed ID: 9675019
[TBL] [Abstract][Full Text] [Related]
18. The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography.
Petschacher B; Leitgeb S; Kavanagh KL; Wilson DK; Nidetzky B
Biochem J; 2005 Jan; 385(Pt 1):75-83. PubMed ID: 15320875
[TBL] [Abstract][Full Text] [Related]
19. Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.
Faucher F; Cantin L; Pereira de Jésus-Tran K; Lemieux M; Luu-The V; Labrie F; Breton R
J Mol Biol; 2007 Jun; 369(2):525-40. PubMed ID: 17442338
[TBL] [Abstract][Full Text] [Related]
20. Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex.
Petrova T; Steuber H; Hazemann I; Cousido-Siah A; Mitschler A; Chung R; Oka M; Klebe G; El-Kabbani O; Joachimiak A; Podjarny A
J Med Chem; 2005 Sep; 48(18):5659-65. PubMed ID: 16134934
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
