These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 21179173)

  • 1. Down-modulation of cancer targets using locked nucleic acid (LNA)-based antisense oligonucleotides without transfection.
    Zhang Y; Qu Z; Kim S; Shi V; Liao B; Kraft P; Bandaru R; Wu Y; Greenberger LM; Horak ID
    Gene Ther; 2011 Apr; 18(4):326-33. PubMed ID: 21179173
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel dual lock method for down-regulation of genes, in which a target mRNA is captured at 2 independent positions by linked locked nucleic acid antisense oligonucleotides.
    Takata R; Makado G; Kitamura A; Watanabe H; Wada T
    RNA Biol; 2016; 13(3):279-89. PubMed ID: 26890856
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A locked nucleic acid antisense oligonucleotide (LNA) silences PCSK9 and enhances LDLR expression in vitro and in vivo.
    Gupta N; Fisker N; Asselin MC; Lindholm M; Rosenbohm C; Ørum H; Elmén J; Seidah NG; Straarup EM
    PLoS One; 2010 May; 5(5):e10682. PubMed ID: 20498851
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design.
    Braasch DA; Liu Y; Corey DR
    Nucleic Acids Res; 2002 Dec; 30(23):5160-7. PubMed ID: 12466540
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA.
    Grünweller A; Wyszko E; Bieber B; Jahnel R; Erdmann VA; Kurreck J
    Nucleic Acids Res; 2003 Jun; 31(12):3185-93. PubMed ID: 12799446
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potent and sustained cellular inhibition of miR-122 by lysine-derivatized peptide nucleic acids (PNA) and phosphorothioate locked nucleic acid (LNA)/2'-O-methyl (OMe) mixmer anti-miRs in the absence of transfection agents.
    Torres AG; Threlfall RN; Gait MJ
    Artif DNA PNA XNA; 2011; 2(3):71-8. PubMed ID: 22567190
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LNA-antisense rivals siRNA for gene silencing.
    Jepsen JS; Wengel J
    Curr Opin Drug Discov Devel; 2004 Mar; 7(2):188-94. PubMed ID: 15603252
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Downregulation of p21(WAF1/CIP1) and estrogen receptor alpha in MCF-7 cells by antisense oligonucleotides containing locked nucleic acid (LNA).
    Jepsen JS; Pfundheller HM; Lykkesfeldt AE
    Oligonucleotides; 2004; 14(2):147-56. PubMed ID: 15294077
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo.
    Mook OR; Baas F; de Wissel MB; Fluiter K
    Mol Cancer Ther; 2007 Mar; 6(3):833-43. PubMed ID: 17363479
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A functionally improved locked nucleic acid antisense oligonucleotide inhibits Bcl-2 and Bcl-xL expression and facilitates tumor cell apoptosis.
    Simões-Wüst AP; Hopkins-Donaldson S; Sigrist B; Belyanskaya L; Stahel RA; Zangemeister-Wittke U
    Oligonucleotides; 2004; 14(3):199-209. PubMed ID: 15625915
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sphingosine kinase 1 is a relevant molecular target in gastric cancer.
    Fuereder T; Hoeflmayer D; Jaeger-Lansky A; Rasin-Streden D; Strommer S; Fisker N; Hansen BJ; Crevenna R; Wacheck V
    Anticancer Drugs; 2011 Mar; 22(3):245-52. PubMed ID: 21360847
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alpha-l-Locked Nucleic Acid-Modified Antisense Oligonucleotides Induce Efficient Splice Modulation In Vitro.
    Raguraman P; Wang T; Ma L; Jørgensen PT; Wengel J; Veedu RN
    Int J Mol Sci; 2020 Mar; 21(7):. PubMed ID: 32244535
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents.
    Stein CA; Hansen JB; Lai J; Wu S; Voskresenskiy A; Høg A; Worm J; Hedtjärn M; Souleimanian N; Miller P; Soifer HS; Castanotto D; Benimetskaya L; Ørum H; Koch T
    Nucleic Acids Res; 2010 Jan; 38(1):e3. PubMed ID: 19854938
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The intratracheal administration of locked nucleic acid containing antisense oligonucleotides induced gene silencing and an immune-stimulatory effect in the murine lung.
    Uemura Y; Hagiwara K; Kobayashi K
    PLoS One; 2017; 12(11):e0187286. PubMed ID: 29107995
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Locked nucleic acid: a potent nucleic acid analog in therapeutics and biotechnology.
    Jepsen JS; Sørensen MD; Wengel J
    Oligonucleotides; 2004; 14(2):130-46. PubMed ID: 15294076
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Non-Coding RNA Silencing in Mammalian Cells by Antisense LNA GapmeRs Transfection.
    Alfeghaly C; Aigueperse C; Maenner S; Behm-Ansmant I
    Methods Mol Biol; 2021; 2300():31-37. PubMed ID: 33792869
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antisense oligonucleotide targeting CD39 improves anti-tumor T cell immunity.
    Kashyap AS; Thelemann T; Klar R; Kallert SM; Festag J; Buchi M; Hinterwimmer L; Schell M; Michel S; Jaschinski F; Zippelius A
    J Immunother Cancer; 2019 Mar; 7(1):67. PubMed ID: 30871609
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Locked nucleic acid containing antisense oligonucleotides enhance inhibition of HIV-1 genome dimerization and inhibit virus replication.
    Elmén J; Zhang HY; Zuber B; Ljungberg K; Wahren B; Wahlestedt C; Liang Z
    FEBS Lett; 2004 Dec; 578(3):285-90. PubMed ID: 15589834
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Zorro locked nucleic acid induces sequence-specific gene silencing.
    Ge R; Heinonen JE; Svahn MG; Mohamed AJ; Lundin KE; Smith CI
    FASEB J; 2007 Jun; 21(8):1902-14. PubMed ID: 17314142
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A structure-activity study of the inhibition of HIV-1 Tat-dependent trans-activation by mixmer 2'-O-methyl oligoribonucleotides containing locked nucleic acid (LNA), alpha-L-LNA, or 2'-thio-LNA residues.
    Arzumanov A; Stetsenko DA; Malakhov AD; Reichelt S; Sørensen MD; Babu BR; Wengel J; Gait MJ
    Oligonucleotides; 2003; 13(6):435-53. PubMed ID: 15025911
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.