These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 21182990)

  • 1. Pyridoxal-5'-phosphate-dependent enzymes involved in biotin biosynthesis: structure, reaction mechanism and inhibition.
    Mann S; Ploux O
    Biochim Biophys Acta; 2011 Nov; 1814(11):1459-66. PubMed ID: 21182990
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme.
    Alexeev D; Alexeeva M; Baxter RL; Campopiano DJ; Webster SP; Sawyer L
    J Mol Biol; 1998 Nov; 284(2):401-19. PubMed ID: 9813126
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanistic studies on the 8-amino-7-oxopelargonate synthase, a pyridoxal-5'-phosphate-dependent enzyme involved in biotin biosynthesis.
    Ploux O; Marquet A
    Eur J Biochem; 1996 Feb; 236(1):301-8. PubMed ID: 8617279
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of 7,8-diaminopelargonic acid aminotransferase by amiclenomycin and analogues.
    Mann S; Marquet A; Ploux O
    Biochem Soc Trans; 2005 Aug; 33(Pt 4):802-5. PubMed ID: 16042602
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biosynthesis of biotin and lipoic acid.
    Marquet A; Bui BT; Florentin D
    Vitam Horm; 2001; 61():51-101. PubMed ID: 11153271
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Slow-binding and competitive inhibition of 8-amino-7-oxopelargonate synthase, a pyridoxal-5'-phosphate-dependent enzyme involved in biotin biosynthesis, by substrate and intermediate analogs. Kinetic and binding studies.
    Ploux O; Breyne O; Carillon S; Marquet A
    Eur J Biochem; 1999 Jan; 259(1-2):63-70. PubMed ID: 9914476
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin.
    Sandmark J; Mann S; Marquet A; Schneider G
    J Biol Chem; 2002 Nov; 277(45):43352-8. PubMed ID: 12218056
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural enzymology of biotin biosynthesis.
    Schneider G; Lindqvist Y
    FEBS Lett; 2001 Apr; 495(1-2):7-11. PubMed ID: 11322938
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and synthesis of potential mechanism-based inhibitors of the aminotransferase BioA involved in biotin biosynthesis.
    Shi C; Aldrich CC
    J Org Chem; 2012 Jul; 77(14):6051-8. PubMed ID: 22724679
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stereospecificity for the hydrogen transfer and molecular evolution of pyridoxal enzymes.
    Yoshimura T; Jhee KH; Soda K
    Biosci Biotechnol Biochem; 1996 Feb; 60(2):181-7. PubMed ID: 9063963
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 7,8-Diaminoperlargonic acid aminotransferase from Mycobacterium tuberculosis, a potential therapeutic target. Characterization and inhibition studies.
    Mann S; Ploux O
    FEBS J; 2006 Oct; 273(20):4778-89. PubMed ID: 16984394
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover.
    Mascarenhas R; Le HV; Clevenger KD; Lehrer HJ; Ringe D; Kelleher NL; Silverman RB; Liu D
    Biochemistry; 2017 Sep; 56(37):4951-4961. PubMed ID: 28816437
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Spectral and kinetic characterization of 7,8-diaminopelargonic acid synthase from Mycobacterium tuberculosis.
    Bhor VM; Dev S; Vasanthakumar GR; Surolia A
    IUBMB Life; 2006 Apr; 58(4):225-33. PubMed ID: 16754301
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate.
    Sivaraman J; Li Y; Larocque R; Schrag JD; Cygler M; Matte A
    J Mol Biol; 2001 Aug; 311(4):761-76. PubMed ID: 11518529
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.
    Liu F; Dawadi S; Maize KM; Dai R; Park SW; Schnappinger D; Finzel BC; Aldrich CC
    J Med Chem; 2017 Jul; 60(13):5507-5520. PubMed ID: 28594172
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of diaminopelargonic acid synthase: evolutionary relationships between pyridoxal-5'-phosphate-dependent enzymes.
    Käck H; Sandmark J; Gibson K; Schneider G; Lindqvist Y
    J Mol Biol; 1999 Aug; 291(4):857-76. PubMed ID: 10452893
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of alpha-oxoamine synthases: identification of the intermediate Claisen product in the 8-amino-7-oxononanoate synthase reaction.
    Kerbarh O; Campopiano DJ; Baxter RL
    Chem Commun (Camb); 2006 Jan; (1):60-2. PubMed ID: 16353092
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Canonical Biotin Synthesis Enzyme, 8-Amino-7-Oxononanoate Synthase (BioF), Utilizes Different Acyl Chain Donors in Bacillus subtilis and Escherichia coli.
    Manandhar M; Cronan JE
    Appl Environ Microbiol; 2018 Jan; 84(1):. PubMed ID: 29054876
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
    Webster SP; Alexeev D; Campopiano DJ; Watt RM; Alexeeva M; Sawyer L; Baxter RL
    Biochemistry; 2000 Jan; 39(3):516-28. PubMed ID: 10642176
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural insights for the substrate recognition mechanism of LL-diaminopimelate aminotransferase.
    Watanabe N; James MN
    Biochim Biophys Acta; 2011 Nov; 1814(11):1528-33. PubMed ID: 21435399
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.