BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

603 related articles for article (PubMed ID: 21183792)

  • 1. Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway.
    Beauchamp EM; Ringer L; Bulut G; Sajwan KP; Hall MD; Lee YC; Peaceman D; Ozdemirli M; Rodriguez O; Macdonald TJ; Albanese C; Toretsky JA; Uren A
    J Clin Invest; 2011 Jan; 121(1):148-60. PubMed ID: 21183792
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Arsenic: a potentially useful poison for Hedgehog-driven cancers.
    Raju GP
    J Clin Invest; 2011 Jan; 121(1):14-6. PubMed ID: 21183780
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro.
    You M; Varona-Santos J; Singh S; Robbins DJ; Savaraj N; Nguyen DM
    J Thorac Cardiovasc Surg; 2014 Jan; 147(1):508-16. PubMed ID: 24094913
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Arsenic trioxide inhibits the Hedgehog pathway which is aberrantly activated in acute promyelocytic leukemia.
    Yang D; Cao F; Ye X; Zhao H; Liu X; Li Y; Shi C; Wang H; Zhou J
    Acta Haematol; 2013; 130(4):260-7. PubMed ID: 23867347
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector.
    Kim J; Lee JJ; Kim J; Gardner D; Beachy PA
    Proc Natl Acad Sci U S A; 2010 Jul; 107(30):13432-7. PubMed ID: 20624968
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel PEGylated liposome-encapsulated SANT75 suppresses tumor growth through inhibiting hedgehog signaling pathway.
    Yuan Y; Zhao Y; Xin S; Wu N; Wen J; Li S; Chen L; Wei Y; Yang H; Lin S
    PLoS One; 2013; 8(4):e60266. PubMed ID: 23560085
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation.
    Nakamura S; Nagano S; Nagao H; Ishidou Y; Yokouchi M; Abematsu M; Yamamoto T; Komiya S; Setoguchi T
    PLoS One; 2013; 8(7):e69466. PubMed ID: 23861973
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth.
    Di Magno L; Manzi D; D'Amico D; Coni S; Macone A; Infante P; Di Marcotullio L; De Smaele E; Ferretti E; Screpanti I; Agostinelli E; Gulino A; Canettieri G
    Cell Cycle; 2014; 13(21):3404-13. PubMed ID: 25485584
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists.
    Kim J; Aftab BT; Tang JY; Kim D; Lee AH; Rezaee M; Kim J; Chen B; King EM; Borodovsky A; Riggins GJ; Epstein EH; Beachy PA; Rudin CM
    Cancer Cell; 2013 Jan; 23(1):23-34. PubMed ID: 23291299
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effective targeting of Hedgehog signaling in a medulloblastoma model with PF-5274857, a potent and selective Smoothened antagonist that penetrates the blood-brain barrier.
    Rohner A; Spilker ME; Lam JL; Pascual B; Bartkowski D; Li QJ; Yang AH; Stevens G; Xu M; Wells PA; Planken S; Nair S; Sun S
    Mol Cancer Ther; 2012 Jan; 11(1):57-65. PubMed ID: 22084163
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A new era for an ancient drug: arsenic trioxide and Hedgehog signaling.
    Beauchamp EM; Uren A
    Vitam Horm; 2012; 88():333-54. PubMed ID: 22391311
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New hedgehog/GLI-signaling inhibitors from Adenium obesum.
    Arai MA; Tateno C; Koyano T; Kowithayakorn T; Kawabe S; Ishibashi M
    Org Biomol Chem; 2011 Feb; 9(4):1133-9. PubMed ID: 21170436
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia.
    Kern D; Regl G; Hofbauer SW; Altenhofer P; Achatz G; Dlugosz A; Schnidar H; Greil R; Hartmann TN; Aberger F
    Oncogene; 2015 Oct; 34(42):5341-51. PubMed ID: 25639866
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1.
    Götschel F; Berg D; Gruber W; Bender C; Eberl M; Friedel M; Sonntag J; Rüngeler E; Hache H; Wierling C; Nietfeld W; Lehrach H; Frischauf A; Schwartz-Albiez R; Aberger F; Korf U
    PLoS One; 2013; 8(6):e65403. PubMed ID: 23762360
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
    Benvenuto M; Masuelli L; De Smaele E; Fantini M; Mattera R; Cucchi D; Bonanno E; Di Stefano E; Frajese GV; Orlandi A; Screpanti I; Gulino A; Modesti A; Bei R
    Oncotarget; 2016 Feb; 7(8):9250-70. PubMed ID: 26843616
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pyrvinium attenuates Hedgehog signaling downstream of smoothened.
    Li B; Fei DL; Flaveny CA; Dahmane N; Baubet V; Wang Z; Bai F; Pei XH; Rodriguez-Blanco J; Hang B; Orton D; Han L; Wang B; Capobianco AJ; Lee E; Robbins DJ
    Cancer Res; 2014 Sep; 74(17):4811-21. PubMed ID: 24994715
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.
    Wickström M; Dyberg C; Shimokawa T; Milosevic J; Baryawno N; Fuskevåg OM; Larsson R; Kogner P; Zaphiropoulos PG; Johnsen JI
    Int J Cancer; 2013 Apr; 132(7):1516-24. PubMed ID: 22949014
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development.
    Milla LA; Cortés CR; Hodar C; Oñate MG; Cambiazo V; Burgess SM; Palma V
    BMC Genomics; 2012 Jan; 13():2. PubMed ID: 22214306
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site.
    Agren M; Kogerman P; Kleman MI; Wessling M; Toftgård R
    Gene; 2004 Apr; 330():101-14. PubMed ID: 15087129
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitogen-activated protein kinases and Hedgehog-GLI signaling in cancer: A crosstalk providing therapeutic opportunities?
    Rovida E; Stecca B
    Semin Cancer Biol; 2015 Dec; 35():154-67. PubMed ID: 26292171
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.