132 related articles for article (PubMed ID: 21185262)
1. Design, synthesis and DNA binding properties of orthogonally positioned diamino containing polyamide f-IPI.
Babu B; Liu Y; Plaunt A; Riddering C; Ogilvie R; Westrate L; Davis R; Ferguson A; Mackay H; Rice T; Chavda S; Wilson D; Lin S; Kiakos K; Hartley JA; Lee M
Biochem Biophys Res Commun; 2011 Jan; 404(3):848-52. PubMed ID: 21185262
[TBL] [Abstract][Full Text] [Related]
2. Novel diamino imidazole and pyrrole-containing polyamides: Synthesis and DNA binding studies of mono- and diamino-phenyl-ImPy*Im polyamides designed to target 5'-ACGCGT-3'.
Satam V; Babu B; Chavda S; Savagian M; Sjoholm R; Tzou S; Ramos J; Liu Y; Kiakos K; Lin S; David Wilson W; Hartley JA; Lee M
Bioorg Med Chem; 2012 Jan; 20(2):693-701. PubMed ID: 22222156
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and DNA binding characteristics of a group of orthogonally positioned diamino, N-formamido, pyrrole- and imidazole-containing polyamides.
Chavda S; Babu B; Patil P; Plaunt A; Ferguson A; Lee M; Tzou S; Sjoholm R; Rice T; Mackay H; Ramos J; Wang S; Lin S; Kiakos K; Wilson WD; Hartley JA; Lee M
Bioorg Med Chem; 2013 Jul; 21(13):3907-18. PubMed ID: 23647824
[TBL] [Abstract][Full Text] [Related]
4. Effects of the N-terminal acylamido group of imidazole- and pyrrole-containing polyamides on DNA sequence specificity and binding affinity.
Westrate L; Mackay H; Brown T; Nguyen B; Kluza J; Wilson WD; Lee M; Hartley JA
Biochemistry; 2009 Jun; 48(24):5679-88. PubMed ID: 19419200
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and DNA binding properties of 1-(3-aminopropyl)-imidazole-containing triamide f-Im*PyIm: a novel diamino polyamide designed to target 5'-ACGCGT-3'.
Satam V; Babu B; Porte A; Savagian M; Lee M; Smeltzer T; Liu Y; Ramos J; Wilson WD; Lin S; Kiakos K; Hartley JA; Lee M
Bioorg Med Chem Lett; 2012 Sep; 22(18):5898-902. PubMed ID: 22892118
[TBL] [Abstract][Full Text] [Related]
6. Sequence recognition in the minor groove of DNA by covalently linked formamido imidazole-pyrrole-imidazole polyamides: effect of H-pin linkage and linker length on selectivity and affinity.
O'Hare CC; Uthe P; Mackay H; Blackmon K; Jones J; Brown T; Nguyen B; Wilson WD; Lee M; Hartley JA
Biochemistry; 2007 Oct; 46(42):11661-70. PubMed ID: 17910471
[TBL] [Abstract][Full Text] [Related]
7. Hx, a novel fluorescent, minor groove and sequence specific recognition element: design, synthesis, and DNA binding properties of p-anisylbenzimidazole-imidazole/pyrrole-containing polyamides.
Chavda S; Liu Y; Babu B; Davis R; Sielaff A; Ruprich J; Westrate L; Tronrud C; Ferguson A; Franks A; Tzou S; Adkins C; Rice T; Mackay H; Kluza J; Tahir SA; Lin S; Kiakos K; Bruce CD; Wilson WD; Hartley JA; Lee M
Biochemistry; 2011 Apr; 50(15):3127-36. PubMed ID: 21388229
[TBL] [Abstract][Full Text] [Related]
8. Modifying the N-terminus of polyamides: PyImPyIm has improved sequence specificity over f-ImPyIm.
Brown T; Mackay H; Turlington M; Sutterfield A; Smith T; Sielaff A; Westrate L; Bruce C; Kluza J; O'Hare C; Nguyen B; Wilson WD; Hartley JA; Lee M
Bioorg Med Chem; 2008 May; 16(9):5266-76. PubMed ID: 18353654
[TBL] [Abstract][Full Text] [Related]
9. Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studies.
Mackay H; Brown T; Uthe PB; Westrate L; Sielaff A; Jones J; Lajiness JP; Kluza J; O'Hare C; Nguyen B; Davis Z; Bruce C; Wilson WD; Hartley JA; Lee M
Bioorg Med Chem; 2008 Oct; 16(20):9145-53. PubMed ID: 18819814
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biophysical evaluation of minor-groove binding C-terminus modified pyrrole and imidazole triamide analogs of distamycin.
Brown T; Taherbhai Z; Sexton J; Sutterfield A; Turlington M; Jones J; Stallings L; Stewart M; Buchmueller K; Mackay H; O'hare C; Kluza J; Nguyen B; Wilson D; Lee M; Hartley JA
Bioorg Med Chem; 2007 Jan; 15(1):474-83. PubMed ID: 17035029
[TBL] [Abstract][Full Text] [Related]
11. Extending the language of DNA molecular recognition by polyamides: unexpected influence of imidazole and pyrrole arrangement on binding affinity and specificity.
Buchmueller KL; Staples AM; Howard CM; Horick SM; Uthe PB; Le NM; Cox KK; Nguyen B; Pacheco KA; Wilson WD; Lee M
J Am Chem Soc; 2005 Jan; 127(2):742-50. PubMed ID: 15643900
[TBL] [Abstract][Full Text] [Related]
12. Polyamide curvature and DNA sequence selective recognition: use of 4-aminobenzamide to adjust curvature.
Lajiness J; Sielaff A; Mackay H; Brown T; Kluza J; Nguyen B; Wilson WD; Lee M; Hartley JA
Med Chem; 2009 May; 5(3):216-26. PubMed ID: 19442211
[TBL] [Abstract][Full Text] [Related]
13. Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
Henry JA; Le NM; Nguyen B; Howard CM; Bailey SL; Horick SM; Buchmueller KL; Kotecha M; Hochhauser D; Hartley JA; Wilson WD; Lee M
Biochemistry; 2004 Sep; 43(38):12249-57. PubMed ID: 15379563
[TBL] [Abstract][Full Text] [Related]
14. Rapid solid-phase synthesis of DNA-binding pyrrole-imidazole polyamides.
Krutzik PO; Chamberlin AR
Bioorg Med Chem Lett; 2002 Aug; 12(16):2129-32. PubMed ID: 12127520
[TBL] [Abstract][Full Text] [Related]
15. Conformational modulation of DNA by polyamide binding: structural effects of f-Im-Py-Im based derivatives on 5'-ACGCGT-3'.
Wang S; Chai Y; Babu B; Satam V; Lee M; David Wilson W
J Mol Recognit; 2013 Aug; 26(8):331-40. PubMed ID: 23784989
[TBL] [Abstract][Full Text] [Related]
16. AzaHx, a novel fluorescent, DNA minor groove and G·C recognition element: Synthesis and DNA binding properties of a p-anisyl-4-aza-benzimidazole-pyrrole-imidazole (azaHx-PI) polyamide.
Satam V; Babu B; Patil P; Brien KA; Olson K; Savagian M; Lee M; Mepham A; Jobe LB; Bingham JP; Pett L; Wang S; Ferrara M; Bruce CD; Wilson WD; Lee M; Hartley JA; Kiakos K
Bioorg Med Chem Lett; 2015 Sep; 25(17):3681-5. PubMed ID: 26122210
[TBL] [Abstract][Full Text] [Related]
17. [Advances in the chemical and biological studies of polyamides].
Zhu SL; Gao PH; Li P; Jiang YY; Zhang DZ
Yao Xue Xue Bao; 2008 Nov; 43(11):1089-93. PubMed ID: 19239025
[TBL] [Abstract][Full Text] [Related]
18. Influence of a terminal formamido group on the sequence recognition of DNA by polyamides.
Lacy ER; Le NM; Price CA; Lee M; Wilson WD
J Am Chem Soc; 2002 Mar; 124(10):2153-63. PubMed ID: 11878969
[TBL] [Abstract][Full Text] [Related]
19. Physical and structural basis for the strong interactions of the -ImPy- central pairing motif in the polyamide f-ImPyIm.
Buchmueller KL; Bailey SL; Matthews DA; Taherbhai ZT; Register JK; Davis ZS; Bruce CD; O'Hare C; Hartley JA; Lee M
Biochemistry; 2006 Nov; 45(45):13551-65. PubMed ID: 17087509
[TBL] [Abstract][Full Text] [Related]
20. Recognition of the DNA minor groove by pyrrole-imidazole polyamides: comparison of desmethyl- and N-methylpyrrole.
Bremer RE; Szewczyk JW; Baird EE; Dervan PB
Bioorg Med Chem; 2000 Aug; 8(8):1947-55. PubMed ID: 11003140
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
