BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 21186299)

  • 1. Hedgehog signaling and therapeutics in pancreatic cancer.
    Kelleher FC
    Carcinogenesis; 2011 Apr; 32(4):445-51. PubMed ID: 21186299
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aberrations and therapeutics involving the developmental pathway Hedgehog in pancreatic cancer.
    Kelleher FC; McDermott R
    Vitam Horm; 2012; 88():355-78. PubMed ID: 22391312
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hedgehog signaling: from the cuirass to the heart of pancreatic cancer.
    Di Marco M; Macchini M; Vecchiarelli S; Sina S; Biasco G
    Pancreatology; 2012; 12(4):388-93. PubMed ID: 22898642
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: molecular mechanisms.
    Singh BN; Fu J; Srivastava RK; Shankar S
    PLoS One; 2011; 6(11):e27306. PubMed ID: 22087285
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rationale for inhibition of the hedgehog pathway paracrine loop in pancreatic adenocarcinoma.
    Dimou A; Syrigos K; Saif MW
    JOP; 2011 Jan; 12(1):1-5. PubMed ID: 21206093
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GALNT1-Mediated Glycosylation and Activation of Sonic Hedgehog Signaling Maintains the Self-Renewal and Tumor-Initiating Capacity of Bladder Cancer Stem Cells.
    Li C; Du Y; Yang Z; He L; Wang Y; Hao L; Ding M; Yan R; Wang J; Fan Z
    Cancer Res; 2016 Mar; 76(5):1273-83. PubMed ID: 26676748
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Blockade of sonic hedgehog signal pathway enhances antiproliferative effect of EGFR inhibitor in pancreatic cancer cells.
    Hu WG; Liu T; Xiong JX; Wang CY
    Acta Pharmacol Sin; 2007 Aug; 28(8):1224-30. PubMed ID: 17640486
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Blockade of hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer.
    Xu FG; Ma QY; Wang Z
    Cancer Lett; 2009 Oct; 283(2):119-24. PubMed ID: 19232458
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hedgehog signaling inhibition by the small molecule smoothened inhibitor GDC-0449 in the bone forming prostate cancer xenograft MDA PCa 118b.
    Karlou M; Lu JF; Wu G; Maity S; Tzelepi V; Navone NM; Hoang A; Logothetis CJ; Efstathiou E
    Prostate; 2012 Nov; 72(15):1638-47. PubMed ID: 22457212
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer.
    Steele NG; Biffi G; Kemp SB; Zhang Y; Drouillard D; Syu L; Hao Y; Oni TE; Brosnan E; Elyada E; Doshi A; Hansma C; Espinoza C; Abbas A; The S; Irizarry-Negron V; Halbrook CJ; Franks NE; Hoffman MT; Brown K; Carpenter ES; Nwosu ZC; Johnson C; Lima F; Anderson MA; Park Y; Crawford HC; Lyssiotis CA; Frankel TL; Rao A; Bednar F; Dlugosz AA; Preall JB; Tuveson DA; Allen BL; Pasca di Magliano M
    Clin Cancer Res; 2021 Apr; 27(7):2023-2037. PubMed ID: 33495315
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer.
    Kumar V; Chaudhary AK; Dong Y; Zhong HA; Mondal G; Lin F; Kumar V; Mahato RI
    Sci Rep; 2017 May; 7(1):1665. PubMed ID: 28490735
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sonic hedgehog paracrine signaling activates stromal cells to promote perineural invasion in pancreatic cancer.
    Li X; Wang Z; Ma Q; Xu Q; Liu H; Duan W; Lei J; Ma J; Wang X; Lv S; Han L; Li W; Guo J; Guo K; Zhang D; Wu E; Xie K
    Clin Cancer Res; 2014 Aug; 20(16):4326-38. PubMed ID: 24947933
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Agents targeting the Hedgehog pathway for pancreatic cancer treatment.
    Bisht S; Brossart P; Maitra A; Feldmann G
    Curr Opin Investig Drugs; 2010 Dec; 11(12):1387-98. PubMed ID: 21154121
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Sonic Hedgehog signaling pathway: from embryology to molecular targeted therapies].
    Watson S; Serrate C; Vignot S
    Bull Cancer; 2010 Dec; 97(12):1477-83. PubMed ID: 21220225
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stroma - A Double-Edged Sword in Pancreatic Cancer: A Lesson From Targeting Stroma in Pancreatic Cancer With Hedgehog Signaling Inhibitors.
    Gu J; Saiyin H; Fu D; Li J
    Pancreas; 2018 Apr; 47(4):382-389. PubMed ID: 29521941
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Terminating the criminal collaboration in pancreatic cancer: Nanoparticle-based synergistic therapy for overcoming fibroblast-induced drug resistance.
    Wang L; Liu X; Zhou Q; Sui M; Lu Z; Zhou Z; Tang J; Miao Y; Zheng M; Wang W; Shen Y
    Biomaterials; 2017 Nov; 144():105-118. PubMed ID: 28837958
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel neutralizing hedgehog antibody MEDI-5304 exhibits antitumor activity by inhibiting paracrine hedgehog signaling.
    Michaud NR; Wang Y; McEachern KA; Jordan JJ; Mazzola AM; Hernandez A; Jalla S; Chesebrough JW; Hynes MJ; Belmonte MA; Wang L; Kang JS; Jovanovic J; Laing N; Jenkins DW; Hurt E; Liang M; Frantz C; Hollingsworth RE; Simeone DM; Blakey DC; Bedian V
    Mol Cancer Ther; 2014 Feb; 13(2):386-98. PubMed ID: 24344235
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pancreatic cancer and hedgehog pathway signaling: new insights.
    Dosch JS; Pasca di Magliano M; Simeone DM
    Pancreatology; 2010; 10(2-3):151-7. PubMed ID: 20453550
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Efficient elimination of pancreatic cancer stem cells by hedgehog/GLI inhibitor GANT61 in combination with mTOR inhibition.
    Miyazaki Y; Matsubara S; Ding Q; Tsukasa K; Yoshimitsu M; Kosai K; Takao S
    Mol Cancer; 2016 Jun; 15(1):49. PubMed ID: 27349387
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Detection of breast cancer stem cells and the expression of key molecules in Hedgehog signaling pathway].
    Lu ZH; Jia J; Ren J; Ma B; DI LJ; Song GH
    Beijing Da Xue Xue Bao Yi Xue Ban; 2008 Oct; 40(5):480-5. PubMed ID: 18931709
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.