BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 21192843)

  • 1. Apogossypolone targets mitochondria and light enhances its anticancer activity by stimulating generation of singlet oxygen and reactive oxygen species.
    Hu ZY; Wang J; Cheng G; Zhu XF; Huang P; Yang D; Zeng YX
    Chin J Cancer; 2011 Jan; 30(1):41-53. PubMed ID: 21192843
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway.
    Hu ZY; Sun J; Zhu XF; Yang D; Zeng YX
    J Transl Med; 2009 Aug; 7():74. PubMed ID: 19698176
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ApoG2, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces apoptosis and suppresses tumor growth in nasopharyngeal carcinoma xenografts.
    Hu ZY; Zhu XF; Zhong ZD; Sun J; Wang J; Yang D; Zeng YX
    Int J Cancer; 2008 Nov; 123(10):2418-29. PubMed ID: 18712728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Apogossypolone, a small-molecule inhibitor of Bcl-2, induces radiosensitization of nasopharyngeal carcinoma cells by stimulating autophagy.
    He JH; Liao XL; Wang W; Li DD; Chen WD; Deng R; Yang D; Han ZP; Jiang JW; Zhu XF
    Int J Oncol; 2014 Sep; 45(3):1099-108. PubMed ID: 24919770
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo.
    Sun Y; Wu J; Aboukameel A; Banerjee S; Arnold AA; Chen J; Nikolovska-Coleska Z; Lin Y; Ling X; Yang D; Wang S; Al-Katib A; Mohammad RM
    Cancer Biol Ther; 2008 Sep; 7(9):1418-26. PubMed ID: 18769131
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in human hepatocellular carcinoma [corrected] cells.
    Cheng P; Ni Z; Dai X; Wang B; Ding W; Rae Smith A; Xu L; Wu D; He F; Lian J
    Cell Death Dis; 2013 Feb; 4(2):e489. PubMed ID: 23392177
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Apogossypolone induces reactive oxygen species accumulation and controls cell cycle progression in Raji Burkkit's lymphoma cells.
    Hu ZY; Xu F; Sun R; Chen YF; Zhang DS; Fan YH; Sun J
    Mol Med Rep; 2015 Jul; 12(1):337-44. PubMed ID: 25738577
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ApoG2 as the most potent gossypol derivatives inhibits cell growth and induces apoptosis on gastric cancer cells.
    Xin J; Zhan YH; Xia LM; Zhu HW; Nie YZ; Liang JM; Tian J
    Biomed Pharmacother; 2013 Feb; 67(1):88-95. PubMed ID: 23201009
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma.
    Mi JX; Wang GF; Wang HB; Sun XQ; Ni XY; Zhang XW; Tang JM; Yang DJ
    Acta Pharmacol Sin; 2008 Dec; 29(12):1467-77. PubMed ID: 19026166
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Apogossypolone induces autophagy and apoptosis in breast cancer MCF-7 cells in vitro and in vivo.
    Niu X; Li S; Wei F; Huang J; Wu G; Xu L; Xu D; Wang S
    Breast Cancer; 2014 Mar; 21(2):223-30. PubMed ID: 22711315
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preclinical studies of apogossypolone, a novel pan inhibitor of bcl-2 and mcl-1, synergistically potentiates cytotoxic effect of gemcitabine in pancreatic cancer cells.
    Banerjee S; Choi M; Aboukameel A; Wang Z; Mohammad M; Chen J; Yang D; Sarkar FH; Mohammad RM
    Pancreas; 2010 Apr; 39(3):323-31. PubMed ID: 19823097
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ApoG2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U937 cells.
    Sun J; Li ZM; Hu ZY; Lin XB; Zhou NN; Xian LJ; Yang DJ; Jiang WQ
    Anticancer Drugs; 2008 Nov; 19(10):967-74. PubMed ID: 18827561
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ApoG2 induces ER stress-dependent apoptosis in gastric cancer cells in vitro and its real-time evaluation by bioluminescence imaging in vivo.
    Xin J; Zhan Y; Liu M; Hu H; Xia L; Nie Y; Wu K; Liang J; Tian J
    Cancer Lett; 2013 Aug; 336(2):260-9. PubMed ID: 23523614
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ApoG2 inhibits the antiapoptotic protein, Mcl‑1, and induces mitochondria‑dependent apoptosis in human colorectal cancer cells.
    Li T; Yuan G; Zhang L; Ye L; Li S; Fan Y; Sun J
    Mol Med Rep; 2015 Nov; 12(5):6976-84. PubMed ID: 26352605
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mobilization of Intracellular Copper by Gossypol and Apogossypolone Leads to Reactive Oxygen Species-Mediated Cell Death: Putative Anticancer Mechanism.
    Zubair H; Azim S; Khan HY; Ullah MF; Wu D; Singh AP; Hadi SM; Ahmad A
    Int J Mol Sci; 2016 Jun; 17(5):. PubMed ID: 27331811
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Apogossypolone induces apoptosis and autophagy in nasopharyngeal carcinoma cells in an
    Zheng R; Chen K; Zhang Y; Huang J; Shi F; Wu G; Wang S
    Oncol Lett; 2017 Jul; 14(1):751-757. PubMed ID: 28693230
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo.
    Zhang X; Hu X; Mu S; Zhan Y; An Q; Liu Z; Huang X
    Mol Med Rep; 2014 Sep; 10(3):1184-94. PubMed ID: 25060748
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nanosystem Integrated with Photosensitizer and Novel Targeting Chemotherapy Agent for Gastric Cancer Chemo-Photodynamic Combined Therapy.
    Xin J; Wang S; Wang J; Wang J; Fu L; Shen L; Zhang Z; Yao C
    J Biomed Nanotechnol; 2018 Aug; 14(8):1430-1447. PubMed ID: 29903058
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Therapeutic effect of TMZ-POH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation.
    Xie L; Song X; Guo W; Wang X; Wei L; Li Y; Lv L; Wang W; Chen TC; Song X
    Oncotarget; 2016 Jan; 7(2):1651-62. PubMed ID: 26625208
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reactive oxygen species-mediated mitochondrial dysfunction is involved in apoptosis in human nasopharyngeal carcinoma CNE cells induced by Selaginella doederleinii extract.
    Liu H; Peng H; Ji Z; Zhao S; Zhang Y; Wu J; Fan J; Liao J
    J Ethnopharmacol; 2011 Oct; 138(1):184-91. PubMed ID: 21924341
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.