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4. Indoxyl sulfate downregulates renal expression of Klotho through production of ROS and activation of nuclear factor-ĸB. Shimizu H; Bolati D; Adijiang A; Adelibieke Y; Muteliefu G; Enomoto A; Higashiyama Y; Higuchi Y; Nishijima F; Niwa T Am J Nephrol; 2011; 33(4):319-24. PubMed ID: 21389697 [TBL] [Abstract][Full Text] [Related]
5. An oral sorbent, AST-120, increases Klotho expression and inhibits cell senescence in the kidney of uremic rats. Adijiang A; Niwa T Am J Nephrol; 2010; 31(2):160-4. PubMed ID: 19955715 [TBL] [Abstract][Full Text] [Related]
6. Stat3 contributes to indoxyl sulfate-induced inflammatory and fibrotic gene expression and cellular senescence. Shimizu H; Yisireyili M; Nishijima F; Niwa T Am J Nephrol; 2012; 36(2):184-9. PubMed ID: 22889746 [TBL] [Abstract][Full Text] [Related]
7. Indoxyl sulfate stimulates renal synthesis of transforming growth factor-beta 1 and progression of renal failure. Miyazaki T; Ise M; Hirata M; Endo K; Ito Y; Seo H; Niwa T Kidney Int Suppl; 1997 Dec; 63():S211-4. PubMed ID: 9407462 [TBL] [Abstract][Full Text] [Related]
8. Indoxyl sulfate increases the gene expressions of TGF-beta 1, TIMP-1 and pro-alpha 1(I) collagen in uremic rat kidneys. Miyazaki T; Ise M; Seo H; Niwa T Kidney Int Suppl; 1997 Nov; 62():S15-22. PubMed ID: 9350672 [TBL] [Abstract][Full Text] [Related]
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10. Indoxyl sulfate induces epithelial-to-mesenchymal transition in rat kidneys and human proximal tubular cells. Bolati D; Shimizu H; Higashiyama Y; Nishijima F; Niwa T Am J Nephrol; 2011; 34(4):318-23. PubMed ID: 21849772 [TBL] [Abstract][Full Text] [Related]
11. Role of indoxyl sulfate in the progression of chronic kidney disease and cardiovascular disease: experimental and clinical effects of oral sorbent AST-120. Niwa T Ther Apher Dial; 2011 Apr; 15(2):120-4. PubMed ID: 21426500 [TBL] [Abstract][Full Text] [Related]
12. Indoxyl sulfate, a uremic toxin, is biotransformed from indoxyl-beta-D-glucoside (indican) in rats. Hou YC; Tsai SY; Chan SL; Yang SY; Chao PD Toxicon; 2008 Sep; 52(3):440-4. PubMed ID: 18619995 [TBL] [Abstract][Full Text] [Related]
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14. Indoxyl sulfate reduces superoxide scavenging activity in the kidneys of normal and uremic rats. Owada S; Goto S; Bannai K; Hayashi H; Nishijima F; Niwa T Am J Nephrol; 2008; 28(3):446-54. PubMed ID: 18160814 [TBL] [Abstract][Full Text] [Related]
15. The protein metabolite hypothesis, a model for the progression of renal failure: an oral adsorbent lowers indoxyl sulfate levels in undialyzed uremic patients. Niwa T; Nomura T; Sugiyama S; Miyazaki T; Tsukushi S; Tsutsui S Kidney Int Suppl; 1997 Nov; 62():S23-8. PubMed ID: 9350673 [TBL] [Abstract][Full Text] [Related]
16. Indoxyl sulfate promotes cardiac fibrosis with enhanced oxidative stress in hypertensive rats. Yisireyili M; Shimizu H; Saito S; Enomoto A; Nishijima F; Niwa T Life Sci; 2013 Jul; 92(24-26):1180-5. PubMed ID: 23702423 [TBL] [Abstract][Full Text] [Related]
17. Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats. Adijiang A; Goto S; Uramoto S; Nishijima F; Niwa T Nephrol Dial Transplant; 2008 Jun; 23(6):1892-901. PubMed ID: 18334529 [TBL] [Abstract][Full Text] [Related]
18. Indoxyl sulfate, a circulating uremic toxin, stimulates the progression of glomerular sclerosis. Niwa T; Ise M J Lab Clin Med; 1994 Jul; 124(1):96-104. PubMed ID: 8035108 [TBL] [Abstract][Full Text] [Related]
19. Indoxyl sulfate and progression of renal failure: effects of a low-protein diet and oral sorbent on indoxyl sulfate production in uremic rats and undialyzed uremic patients. Niwa T; Tsukushi S; Ise M; Miyazaki T; Tsubakihara Y; Owada A; Shiigai T Miner Electrolyte Metab; 1997; 23(3-6):179-84. PubMed ID: 9387112 [TBL] [Abstract][Full Text] [Related]
20. Indoxyl sulfate-lowering capacity of oral sorbents affects the prognosis of kidney function and oxidative stress in chronic kidney disease. Taki K; Niwa T J Ren Nutr; 2007 Jan; 17(1):48-52. PubMed ID: 17198932 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]