205 related articles for article (PubMed ID: 21199326)
1. P60TRP interferes with the GPCR/secretase pathway to mediate neuronal survival and synaptogenesis.
Mishra M; Heese K
J Cell Mol Med; 2011 Nov; 15(11):2462-77. PubMed ID: 21199326
[TBL] [Abstract][Full Text] [Related]
2. Brain-site-specific proteome changes induced by neuronal P60TRP expression.
Manavalan A; Mishra M; Sze SK; Heese K
Neurosignals; 2013; 21(3-4):129-49. PubMed ID: 23391701
[TBL] [Abstract][Full Text] [Related]
3. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
[TBL] [Abstract][Full Text] [Related]
4. Calpain activation promotes BACE1 expression, amyloid precursor protein processing, and amyloid plaque formation in a transgenic mouse model of Alzheimer disease.
Liang B; Duan BY; Zhou XP; Gong JX; Luo ZG
J Biol Chem; 2010 Sep; 285(36):27737-44. PubMed ID: 20595388
[TBL] [Abstract][Full Text] [Related]
5. NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.
Buggia-Prevot V; Sevalle J; Rossner S; Checler F
J Biol Chem; 2008 Apr; 283(15):10037-47. PubMed ID: 18263584
[TBL] [Abstract][Full Text] [Related]
6. Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.
Dewachter I; Reversé D; Caluwaerts N; Ris L; Kuipéri C; Van den Haute C; Spittaels K; Umans L; Serneels L; Thiry E; Moechars D; Mercken M; Godaux E; Van Leuven F
J Neurosci; 2002 May; 22(9):3445-53. PubMed ID: 11978821
[TBL] [Abstract][Full Text] [Related]
7. A GPCR/secretase complex regulates beta- and gamma-secretase specificity for Abeta production and contributes to AD pathogenesis.
Teng L; Zhao J; Wang F; Ma L; Pei G
Cell Res; 2010 Feb; 20(2):138-53. PubMed ID: 20066010
[TBL] [Abstract][Full Text] [Related]
8. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
[TBL] [Abstract][Full Text] [Related]
9. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
10. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
[TBL] [Abstract][Full Text] [Related]
11. Berberine Alleviates Amyloid-Beta Pathology in the Brain of APP/PS1 Transgenic Mice via Inhibiting β/γ-Secretases Activity and Enhancing α-Secretases.
Cai Z; Wang C; He W; Chen Y
Curr Alzheimer Res; 2018; 15(11):1045-1052. PubMed ID: 29962345
[TBL] [Abstract][Full Text] [Related]
12. Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Andrew RJ; Fernandez CG; Stanley M; Jiang H; Nguyen P; Rice RC; Buggia-Prévot V; De Rossi P; Vetrivel KS; Lamb R; Argemi A; Allaert ES; Rathbun EM; Krause SV; Wagner SL; Parent AT; Holtzman DM; Thinakaran G
Proc Natl Acad Sci U S A; 2017 Nov; 114(45):E9665-E9674. PubMed ID: 29078331
[TBL] [Abstract][Full Text] [Related]
13. SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.
Kurkinen KM; Marttinen M; Turner L; Natunen T; Mäkinen P; Haapalinna F; Sarajärvi T; Gabbouj S; Kurki M; Paananen J; Koivisto AM; Rauramaa T; Leinonen V; Tanila H; Soininen H; Lucas FR; Haapasalo A; Hiltunen M
J Cell Sci; 2016 Jun; 129(11):2224-38. PubMed ID: 27084579
[TBL] [Abstract][Full Text] [Related]
14. Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane.
Wang M; Jing T; Wang X; Yao D
Neurosci Lett; 2018 Oct; 685():63-67. PubMed ID: 30120949
[TBL] [Abstract][Full Text] [Related]
15. Bispecific Antibody Fragment Targeting APP and Inducing α-Site Cleavage Restores Neuronal Health in an Alzheimer's Mouse Model.
He P; Xin W; Schulz P; Sierks MR
Mol Neurobiol; 2019 Nov; 56(11):7420-7432. PubMed ID: 31041656
[TBL] [Abstract][Full Text] [Related]
16. Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer's disease transgenic mice.
Kimura R; Devi L; Ohno M
J Neurochem; 2010 Apr; 113(1):248-61. PubMed ID: 20089133
[TBL] [Abstract][Full Text] [Related]
17. Neuroprotective role of MMP-9 overexpression in the brain of Alzheimer's 5xFAD mice.
Fragkouli A; Tsilibary EC; Tzinia AK
Neurobiol Dis; 2014 Oct; 70():179-89. PubMed ID: 25008761
[TBL] [Abstract][Full Text] [Related]
18. Genetic reductions of beta-site amyloid precursor protein-cleaving enzyme 1 and amyloid-beta ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer's disease model mice.
Devi L; Ohno M
Eur J Neurosci; 2010 Jan; 31(1):110-8. PubMed ID: 20092558
[TBL] [Abstract][Full Text] [Related]
19. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
Sankaranarayanan S; Price EA; Wu G; Crouthamel MC; Shi XP; Tugusheva K; Tyler KX; Kahana J; Ellis J; Jin L; Steele T; Stachel S; Coburn C; Simon AJ
J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464
[TBL] [Abstract][Full Text] [Related]
20. BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism.
Stern AL; Ghura S; Gannon PJ; Akay-Espinoza C; Phan JM; Yee AC; Vassar R; Gelman BB; Kolson DL; Jordan-Sciutto KL
J Neurosci; 2018 May; 38(18):4288-4300. PubMed ID: 29632166
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]