516 related articles for article (PubMed ID: 21199859)
1. Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic beta-cells.
Hatanaka M; Tanabe K; Yanai A; Ohta Y; Kondo M; Akiyama M; Shinoda K; Oka Y; Tanizawa Y
Hum Mol Genet; 2011 Apr; 20(7):1274-84. PubMed ID: 21199859
[TBL] [Abstract][Full Text] [Related]
2. WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.
Yamada T; Ishihara H; Tamura A; Takahashi R; Yamaguchi S; Takei D; Tokita A; Satake C; Tashiro F; Katagiri H; Aburatani H; Miyazaki J; Oka Y
Hum Mol Genet; 2006 May; 15(10):1600-9. PubMed ID: 16571599
[TBL] [Abstract][Full Text] [Related]
3. Expressional and functional studies of Wolframin, the gene function deficient in Wolfram syndrome, in mice and patient cells.
Philbrook C; Fritz E; Weiher H
Exp Gerontol; 2005; 40(8-9):671-8. PubMed ID: 16087305
[TBL] [Abstract][Full Text] [Related]
4. Vacuolar-type H+-ATPase V1A subunit is a molecular partner of Wolfram syndrome 1 (WFS1) protein, which regulates its expression and stability.
Gharanei S; Zatyka M; Astuti D; Fenton J; Sik A; Nagy Z; Barrett TG
Hum Mol Genet; 2013 Jan; 22(2):203-17. PubMed ID: 23035048
[TBL] [Abstract][Full Text] [Related]
5. Activation of GLP-1 receptor signalling alleviates cellular stresses and improves beta cell function in a mouse model of Wolfram syndrome.
Kondo M; Tanabe K; Amo-Shiinoki K; Hatanaka M; Morii T; Takahashi H; Seino S; Yamada Y; Tanizawa Y
Diabetologia; 2018 Oct; 61(10):2189-2201. PubMed ID: 30054673
[TBL] [Abstract][Full Text] [Related]
6. [Wolfram syndrome: clinical features, molecular genetics of WFS1 gene].
Tanabe K; Matsunaga K; Hatanaka M; Akiyama M; Tanizawa Y
Nihon Rinsho; 2015 Feb; 73(2):341-9. PubMed ID: 25764693
[TBL] [Abstract][Full Text] [Related]
7. Loss of Function of WFS1 Causes ER Stress-Mediated Inflammation in Pancreatic Beta-Cells.
Morikawa S; Blacher L; Onwumere C; Urano F
Front Endocrinol (Lausanne); 2022; 13():849204. PubMed ID: 35399956
[TBL] [Abstract][Full Text] [Related]
8. Wolfram syndrome 1 and Wolfram syndrome 2.
Rigoli L; Di Bella C
Curr Opin Pediatr; 2012 Aug; 24(4):512-7. PubMed ID: 22790102
[TBL] [Abstract][Full Text] [Related]
9. RNA-sequencing of WFS1-deficient pancreatic islets.
Ivask M; Hugill A; Kõks S
Physiol Rep; 2016 Apr; 4(7):. PubMed ID: 27053292
[TBL] [Abstract][Full Text] [Related]
10. Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis.
Riggs AC; Bernal-Mizrachi E; Ohsugi M; Wasson J; Fatrai S; Welling C; Murray J; Schmidt RE; Herrera PL; Permutt MA
Diabetologia; 2005 Nov; 48(11):2313-21. PubMed ID: 16215705
[TBL] [Abstract][Full Text] [Related]
11. [Genetic diagnosis of diabetes mellitus: Wolfram syndrome--from positional cloning to DNA diagnosis].
Tanizawa Y
Rinsho Byori; 2003 Jun; 51(6):544-9. PubMed ID: 12884741
[TBL] [Abstract][Full Text] [Related]
12. Wolfram syndrome and WFS1 gene.
Rigoli L; Lombardo F; Di Bella C
Clin Genet; 2011 Feb; 79(2):103-17. PubMed ID: 20738327
[TBL] [Abstract][Full Text] [Related]
13. Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells.
Fonseca SG; Ishigaki S; Oslowski CM; Lu S; Lipson KL; Ghosh R; Hayashi E; Ishihara H; Oka Y; Permutt MA; Urano F
J Clin Invest; 2010 Mar; 120(3):744-55. PubMed ID: 20160352
[TBL] [Abstract][Full Text] [Related]
14. ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress.
Yamaguchi S; Ishihara H; Yamada T; Tamura A; Usui M; Tominaga R; Munakata Y; Satake C; Katagiri H; Tashiro F; Aburatani H; Tsukiyama-Kohara K; Miyazaki J; Sonenberg N; Oka Y
Cell Metab; 2008 Mar; 7(3):269-76. PubMed ID: 18316032
[TBL] [Abstract][Full Text] [Related]
15. WFS1 protein modulates the free Ca(2+) concentration in the endoplasmic reticulum.
Takei D; Ishihara H; Yamaguchi S; Yamada T; Tamura A; Katagiri H; Maruyama Y; Oka Y
FEBS Lett; 2006 Oct; 580(24):5635-40. PubMed ID: 16989814
[TBL] [Abstract][Full Text] [Related]
16. Wolfram/DIDMOAD syndrome, a heterogenic and molecularly complex neurodegenerative disease.
Domenech E; Gomez-Zaera M; Nunes V
Pediatr Endocrinol Rev; 2006 Mar; 3(3):249-57. PubMed ID: 16639390
[TBL] [Abstract][Full Text] [Related]
17. Mutational spectrum of the WFS1 gene in Wolfram syndrome, nonsyndromic hearing impairment, diabetes mellitus, and psychiatric disease.
Cryns K; Sivakumaran TA; Van den Ouweland JM; Pennings RJ; Cremers CW; Flothmann K; Young TL; Smith RJ; Lesperance MM; Van Camp G
Hum Mutat; 2003 Oct; 22(4):275-87. PubMed ID: 12955714
[TBL] [Abstract][Full Text] [Related]
18. A novel heterozygous mutation of the WFS1 gene leading to constitutive endoplasmic reticulum stress is the cause of Wolfram syndrome.
Morikawa S; Tajima T; Nakamura A; Ishizu K; Ariga T
Pediatr Diabetes; 2017 Dec; 18(8):934-941. PubMed ID: 28271591
[TBL] [Abstract][Full Text] [Related]
19. A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse.
Wang J; Takeuchi T; Tanaka S; Kubo SK; Kayo T; Lu D; Takata K; Koizumi A; Izumi T
J Clin Invest; 1999 Jan; 103(1):27-37. PubMed ID: 9884331
[TBL] [Abstract][Full Text] [Related]
20. Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion.
Ishihara H; Takeda S; Tamura A; Takahashi R; Yamaguchi S; Takei D; Yamada T; Inoue H; Soga H; Katagiri H; Tanizawa Y; Oka Y
Hum Mol Genet; 2004 Jun; 13(11):1159-70. PubMed ID: 15056606
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
