BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 21204013)

  • 1. Phosphorylation of Rictor at Thr1135 impairs the Rictor/Cullin-1 complex to ubiquitinate SGK1.
    Gao D; Wan L; Wei W
    Protein Cell; 2010 Oct; 1(10):881-5. PubMed ID: 21204013
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.
    Gao D; Wan L; Inuzuka H; Berg AH; Tseng A; Zhai B; Shaik S; Bennett E; Tron AE; Gasser JA; Lau A; Gygi SP; Harper JW; DeCaprio JA; Toker A; Wei W
    Mol Cell; 2010 Sep; 39(5):797-808. PubMed ID: 20832730
    [TBL] [Abstract][Full Text] [Related]  

  • 3. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
    García-Martínez JM; Alessi DR
    Biochem J; 2008 Dec; 416(3):375-85. PubMed ID: 18925875
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation.
    Koo J; Wu X; Mao Z; Khuri FR; Sun SY
    J Biol Chem; 2015 May; 290(22):14120-9. PubMed ID: 25897075
    [TBL] [Abstract][Full Text] [Related]  

  • 5. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA; Carriere A; Moreau J; Roux PP
    Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt.
    Yu Z; Chen J; Takagi E; Wang F; Saha B; Liu X; Joubert LM; Gleason CE; Jin M; Li C; Nowotny C; Agard D; Cheng Y; Pearce D
    J Biol Chem; 2022 Sep; 298(9):102288. PubMed ID: 35926713
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of rictor as a novel substrate of Polo-like kinase 1.
    Shao T; Liu X
    Cell Cycle; 2015; 14(5):755-60. PubMed ID: 25714006
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines.
    Lee SL; Chou CC; Chuang HC; Hsu EC; Chiu PC; Kulp SK; Byrd JC; Chen CS
    PLoS One; 2013; 8(6):e67149. PubMed ID: 23840605
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2.
    Boulbes D; Chen CH; Shaikenov T; Agarwal NK; Peterson TR; Addona TA; Keshishian H; Carr SA; Magnuson MA; Sabatini DM; Sarbassov dos D
    Mol Cancer Res; 2010 Jun; 8(6):896-906. PubMed ID: 20501647
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation.
    Fang Z; Zhang T; Dizeyi N; Chen S; Wang H; Swanson KD; Cai C; Balk SP; Yuan X
    J Biol Chem; 2012 Jan; 287(3):2090-8. PubMed ID: 22139837
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling.
    Scheufele F; Wolf B; Kruse M; Hartmann T; Lempart J; Mühlich S; Pfeiffer AFH; Field LJ; Charron MJ; Pan ZQ; Engelhardt S; Sarikas A
    Cell Signal; 2014 Feb; 26(2):233-239. PubMed ID: 24219910
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.
    Jacinto E; Facchinetti V; Liu D; Soto N; Wei S; Jung SY; Huang Q; Qin J; Su B
    Cell; 2006 Oct; 127(1):125-37. PubMed ID: 16962653
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potassium Activates mTORC2-dependent SGK1 Phosphorylation to Stimulate Epithelial Sodium Channel: Role in Rapid Renal Responses to Dietary Potassium.
    Saha B; Shabbir W; Takagi E; Duan XP; Leite Dellova DCA; Demko J; Manis A; Loffing-Cueni D; Loffing J; Sørensen MV; Wang WH; Pearce D
    J Am Soc Nephrol; 2023 Jun; 34(6):1019-1038. PubMed ID: 36890646
    [TBL] [Abstract][Full Text] [Related]  

  • 14. mTOR complex-2 activates ENaC by phosphorylating SGK1.
    Lu M; Wang J; Jones KT; Ives HE; Feldman ME; Yao LJ; Shokat KM; Ashrafi K; Pearce D
    J Am Soc Nephrol; 2010 May; 21(5):811-8. PubMed ID: 20338997
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of 14-3-3 binding to Rictor of mTORC2 for Akt phosphorylation at Ser473 is regulated by selenoprotein W.
    Jeon YH; Park YH; Kwon JH; Lee JH; Kim IY
    Biochim Biophys Acta; 2013 Oct; 1833(10):2135-42. PubMed ID: 23680186
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.
    Pearce LR; Sommer EM; Sakamoto K; Wullschleger S; Alessi DR
    Biochem J; 2011 May; 436(1):169-79. PubMed ID: 21413931
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in β1 integrin-mediated cell survival.
    Riaz A; Zeller KS; Johansson S
    PLoS One; 2012; 7(2):e32081. PubMed ID: 22384145
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.
    Sarbassov DD; Guertin DA; Ali SM; Sabatini DM
    Science; 2005 Feb; 307(5712):1098-101. PubMed ID: 15718470
    [TBL] [Abstract][Full Text] [Related]  

  • 19. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
    Le Bacquer O; Queniat G; Gmyr V; Kerr-Conte J; Lefebvre B; Pattou F
    J Endocrinol; 2013 Jan; 216(1):21-9. PubMed ID: 23092880
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
    J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.