117 related articles for article (PubMed ID: 21209248)
1. Role of catechol-O-methyltransferase in the disposition of luteolin in rats.
Chen Z; Chen M; Pan H; Sun S; Li L; Zeng S; Jiang H
Drug Metab Dispos; 2011 Apr; 39(4):667-74. PubMed ID: 21209248
[TBL] [Abstract][Full Text] [Related]
2. Metabolic Disposition of Luteolin Is Mediated by the Interplay of UDP-Glucuronosyltransferases and Catechol-O-Methyltransferases in Rats.
Wang L; Chen Q; Zhu L; Li Q; Zeng X; Lu L; Hu M; Wang X; Liu Z
Drug Metab Dispos; 2017 Mar; 45(3):306-315. PubMed ID: 28031430
[TBL] [Abstract][Full Text] [Related]
3. Luteolin is a rare substrate of human catechol-O-methyltransferase favoring a para-methylation.
Chen ZJ; Dai YQ; Kong SS; Song FF; Li LP; Ye JF; Wang RW; Zeng S; Zhou H; Jiang HD
Mol Nutr Food Res; 2013 May; 57(5):877-85. PubMed ID: 23386290
[TBL] [Abstract][Full Text] [Related]
4. Catechol metabolites of polychlorinated biphenyls inhibit the catechol-O-methyltransferase-mediated metabolism of catechol estrogens.
Garner CE; Burka LT; Etheridge AE; Matthews HB
Toxicol Appl Pharmacol; 2000 Jan; 162(2):115-23. PubMed ID: 10637135
[TBL] [Abstract][Full Text] [Related]
5. 17 beta-estradiol metabolism by hamster hepatic microsomes: comparison of catechol estrogen O-methylation with catechol estrogen oxidation and glutathione conjugation.
Butterworth M; Lau SS; Monks TJ
Chem Res Toxicol; 1996 Jun; 9(4):793-9. PubMed ID: 8831825
[TBL] [Abstract][Full Text] [Related]
6. 17 beta-Estradiol metabolism by hamster hepatic microsomes. Implications for the catechol-O-methyl transferase-mediated detoxication of catechol estrogens.
Butterworth M; Lau SS; Monks TJ
Drug Metab Dispos; 1996 May; 24(5):588-94. PubMed ID: 8723741
[TBL] [Abstract][Full Text] [Related]
7. Methylation and its role in the disposition of tanshinol, a cardiovascular carboxylic catechol from Salvia miltiorrhiza roots (Danshen).
Tian DD; Jia WW; Liu XW; Wang DD; Liu JH; Dong JJ; Li L; Du FF; Xu F; Wang FQ; Sun Y; Huang YX; Li MJ; Hu LH; Zhu Y; Gao XM; Li C; Yang JL
Acta Pharmacol Sin; 2015 May; 36(5):627-43. PubMed ID: 25891082
[TBL] [Abstract][Full Text] [Related]
8. Comparative study of ortho- and meta-nitrated inhibitors of catechol-O-methyltransferase: interactions with the active site and regioselectivity of O-methylation.
Palma PN; Rodrigues ML; Archer M; Bonifácio MJ; Loureiro AI; Learmonth DA; Carrondo MA; Soares-da-Silva P
Mol Pharmacol; 2006 Jul; 70(1):143-53. PubMed ID: 16618795
[TBL] [Abstract][Full Text] [Related]
9. Identification of major metabolites of the catechol-O-methyltransferase inhibitor entacapone in rats and humans.
Wikberg T; Vuorela A; Ottoila P; Taskinen J
Drug Metab Dispos; 1993; 21(1):81-92. PubMed ID: 8095232
[TBL] [Abstract][Full Text] [Related]
10. Molecular modeling and metabolic studies of the interaction of catechol-O-methyltransferase and a new nitrocatechol inhibitor.
Palma PN; Bonifácio MJ; Loureiro AI; Wright LC; Learmonth DA; Soares-da-Silva P
Drug Metab Dispos; 2003 Mar; 31(3):250-8. PubMed ID: 12584150
[TBL] [Abstract][Full Text] [Related]
11. Computational studies of the regioselectivities of COMT-catalyzed meta-/para-O methylations of luteolin and quercetin.
Cao Y; Chen ZJ; Jiang HD; Chen JZ
J Phys Chem B; 2014 Jan; 118(2):470-81. PubMed ID: 24354565
[TBL] [Abstract][Full Text] [Related]
12. Pharmacokinetics and pharmacodynamics of entacapone and tolcapone after acute and repeated administration: a comparative study in the rat.
Forsberg M; Lehtonen M; Heikkinen M; Savolainen J; Järvinen T; Männistö PT
J Pharmacol Exp Ther; 2003 Feb; 304(2):498-506. PubMed ID: 12538800
[TBL] [Abstract][Full Text] [Related]
13. Pharmacokinetic study of luteolin, apigenin, chrysoeriol and diosmetin after oral administration of Flos Chrysanthemi extract in rats.
Chen Z; Kong S; Song F; Li L; Jiang H
Fitoterapia; 2012 Dec; 83(8):1616-22. PubMed ID: 22999990
[TBL] [Abstract][Full Text] [Related]
14. Simultaneous inhibition of catechol-O-methyltransferase and monoamine oxidase A: effects on hemodynamics and catecholamine metabolism in healthy volunteers.
Illi A; Sundberg S; Ojala-Karlsson P; Scheinin M; Gordin A
Clin Pharmacol Ther; 1996 Apr; 59(4):450-7. PubMed ID: 8612391
[TBL] [Abstract][Full Text] [Related]
15. Enantioselectivity in the methylation of the catecholic phase I metabolites of methylenedioxy designer drugs and their capability to inhibit catechol-O-methyltransferase-catalyzed dopamine 3-methylation.
Meyer MR; Maurer HH
Chem Res Toxicol; 2009 Jun; 22(6):1205-11. PubMed ID: 19462939
[TBL] [Abstract][Full Text] [Related]
16. The disposition of the tolcapone 3-O-methylated metabolite is affected by the route of administration in rats.
Funaki T; Onodera H; Ushiyama N; Tsukamoto Y; Tagami C; Fukazawa H; Kuruma I
J Pharm Pharmacol; 1994 Jul; 46(7):571-4. PubMed ID: 7996385
[TBL] [Abstract][Full Text] [Related]
17. Effects of nebicapone on levodopa pharmacokinetics, catechol-O-methyltransferase activity, and motor fluctuations in patients with Parkinson disease.
Ferreira JJ; Almeida L; Cunha L; Ticmeanu M; Rosa MM; Januário C; Mitu CE; Coelho M; Correia-Guedes L; Morgadinho A; Nunes T; Wright LC; Falcão A; Sampaio C; Soares-da-Silva P
Clin Neuropharmacol; 2008; 31(1):2-18. PubMed ID: 18303486
[TBL] [Abstract][Full Text] [Related]
18. Metabolism of salvianolic acid A and antioxidant activities of its methylated metabolites.
Xu H; Li Y; Che X; Tian H; Fan H; Liu K
Drug Metab Dispos; 2014 Feb; 42(2):274-81. PubMed ID: 24277725
[TBL] [Abstract][Full Text] [Related]
19. Development of a physiologically based pharmacokinetic/pharmacodynamic model to identify mechanisms contributing to entacapone low bioavailability.
Alqahtani S; Kaddoumi A
Biopharm Drug Dispos; 2015 Dec; 36(9):587-602. PubMed ID: 26295926
[TBL] [Abstract][Full Text] [Related]
20. Catechol metabolites of zeranol and 17β-estradiol: a comparative in vitro study on the induction of oxidative DNA damage and methylation by catechol-O-methyltransferase.
Fleck SC; Hildebrand AA; Pfeiffer E; Metzler M
Toxicol Lett; 2012 Apr; 210(1):9-14. PubMed ID: 22285433
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]