494 related articles for article (PubMed ID: 21211982)
1. Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation.
Luo W; Li YP; He Y; Huang SL; Tan JH; Ou TM; Li D; Gu LQ; Huang ZS
Bioorg Med Chem; 2011 Jan; 19(2):763-70. PubMed ID: 21211982
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.
Luo W; Li YP; He Y; Huang SL; Li D; Gu LQ; Huang ZS
Eur J Med Chem; 2011 Jun; 46(6):2609-16. PubMed ID: 21497959
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as multi-targeted compounds against Alzheimer's disease.
Zhang C; Du QY; Chen LD; Wu WH; Liao SY; Yu LH; Liang XT
Eur J Med Chem; 2016 Jun; 116():200-209. PubMed ID: 27061983
[TBL] [Abstract][Full Text] [Related]
4. Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.
Tang H; Zhao LZ; Zhao HT; Huang SL; Zhong SM; Qin JK; Chen ZF; Huang ZS; Liang H
Eur J Med Chem; 2011 Oct; 46(10):4970-9. PubMed ID: 21871694
[TBL] [Abstract][Full Text] [Related]
5. Benzophenone-based derivatives: a novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Belluti F; Bartolini M; Bottegoni G; Bisi A; Cavalli A; Andrisano V; Rampa A
Eur J Med Chem; 2011 May; 46(5):1682-93. PubMed ID: 21397996
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of cholinesterase activity and amyloid aggregation by berberine-phenyl-benzoheterocyclic and tacrine-phenyl-benzoheterocyclic hybrids.
Huang L; Su T; Shan W; Luo Z; Sun Y; He F; Li X
Bioorg Med Chem; 2012 May; 20(9):3038-48. PubMed ID: 22472046
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and evaluation of flavonoid derivatives as potential multifunctional acetylcholinesterase inhibitors against Alzheimer's disease.
Li RS; Wang XB; Hu XJ; Kong LY
Bioorg Med Chem Lett; 2013 May; 23(9):2636-41. PubMed ID: 23511019
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.
Chao X; He X; Yang Y; Zhou X; Jin M; Liu S; Cheng Z; Liu P; Wang Y; Yu J; Tan Y; Huang Y; Qin J; Rapposelli S; Pi R
Bioorg Med Chem Lett; 2012 Oct; 22(20):6498-502. PubMed ID: 22981331
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis and evaluation of isaindigotone derivatives as dual inhibitors for acetylcholinesterase and amyloid beta aggregation.
Yan JW; Li YP; Ye WJ; Chen SB; Hou JQ; Tan JH; Ou TM; Li D; Gu LQ; Huang ZS
Bioorg Med Chem; 2012 Apr; 20(8):2527-34. PubMed ID: 22444876
[TBL] [Abstract][Full Text] [Related]
10. Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Camps P; Formosa X; Galdeano C; Gómez T; Muñoz-Torrero D; Scarpellini M; Viayna E; Badia A; Clos MV; Camins A; Pallàs M; Bartolini M; Mancini F; Andrisano V; Estelrich J; Lizondo M; Bidon-Chanal A; Luque FJ
J Med Chem; 2008 Jun; 51(12):3588-98. PubMed ID: 18517184
[TBL] [Abstract][Full Text] [Related]
11. [Design, synthesis and evaluation of tacrine-methoxybenzene hybrids as cholinesterases inhibitors].
Luo W; Zhao YM; Zhang Z; Su YB; Wang CJ
Yao Xue Xue Bao; 2012 Jul; 47(7):916-21. PubMed ID: 22993857
[TBL] [Abstract][Full Text] [Related]
12. Novel multipotent phenylthiazole-tacrine hybrids for the inhibition of cholinesterase activity, β-amyloid aggregation and Ca²⁺ overload.
Wang Y; Wang F; Yu JP; Jiang FC; Guan XL; Wang CM; Li L; Cao H; Li MX; Chen JG
Bioorg Med Chem; 2012 Nov; 20(21):6513-22. PubMed ID: 23000296
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis and evaluation of novel tacrine-rhein hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Li SY; Jiang N; Xie SS; Wang KD; Wang XB; Kong LY
Org Biomol Chem; 2014 Feb; 12(5):801-14. PubMed ID: 24310227
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.
Keri RS; Quintanova C; Marques SM; Esteves AR; Cardoso SM; Santos MA
Bioorg Med Chem; 2013 Aug; 21(15):4559-69. PubMed ID: 23768661
[TBL] [Abstract][Full Text] [Related]
15. Syntheses of coumarin-tacrine hybrids as dual-site acetylcholinesterase inhibitors and their activity against butylcholinesterase, Aβ aggregation, and β-secretase.
Sun Q; Peng DY; Yang SG; Zhu XL; Yang WC; Yang GF
Bioorg Med Chem; 2014 Sep; 22(17):4784-91. PubMed ID: 25088549
[TBL] [Abstract][Full Text] [Related]
16. Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
Camps P; Formosa X; Galdeano C; Muñoz-Torrero D; Ramírez L; Gómez E; Isambert N; Lavilla R; Badia A; Clos MV; Bartolini M; Mancini F; Andrisano V; Arce MP; Rodríguez-Franco MI; Huertas O; Dafni T; Luque FJ
J Med Chem; 2009 Sep; 52(17):5365-79. PubMed ID: 19663388
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Lan JS; Xie SS; Li SY; Pan LF; Wang XB; Kong LY
Bioorg Med Chem; 2014 Nov; 22(21):6089-104. PubMed ID: 25282654
[TBL] [Abstract][Full Text] [Related]
18. New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and β-amyloid-reducing properties.
Fernández-Bachiller MI; Pérez C; Monjas L; Rademann J; Rodríguez-Franco MI
J Med Chem; 2012 Feb; 55(3):1303-17. PubMed ID: 22243648
[TBL] [Abstract][Full Text] [Related]
19. Tacrine-flurbiprofen hybrids as multifunctional drug candidates for the treatment of Alzheimer's disease.
Chen Y; Sun J; Peng S; Liao H; Zhang Y; Lehmann J
Arch Pharm (Weinheim); 2013 Dec; 346(12):865-71. PubMed ID: 24203864
[TBL] [Abstract][Full Text] [Related]
20. New potent human acetylcholinesterase inhibitors in the tetracyclic triterpene series with inhibitory potency on amyloid β aggregation.
Rouleau J; Iorga BI; Guillou C
Eur J Med Chem; 2011 Jun; 46(6):2193-205. PubMed ID: 21435752
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
