BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 21212363)

  • 41. Delta-like 4-mediated Notch signaling is required for early T-cell development in a three-dimensional thymic structure.
    Hirano K; Negishi N; Yazawa M; Yagita H; Habu S; Hozumi K
    Eur J Immunol; 2015 Aug; 45(8):2252-62. PubMed ID: 25976373
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.
    Medyouf H; Gao X; Armstrong F; Gusscott S; Liu Q; Gedman AL; Matherly LH; Schultz KR; Pflumio F; You MJ; Weng AP
    Blood; 2010 Feb; 115(6):1175-84. PubMed ID: 20008304
    [TBL] [Abstract][Full Text] [Related]  

  • 43. A delta T-cell receptor deleting element transgenic reporter construct is rearranged in alpha beta but not gamma delta T-cell lineages.
    Shutter J; Cain JA; Ledbetter S; Rogers MD; Hockett RD
    Mol Cell Biol; 1995 Dec; 15(12):7022-31. PubMed ID: 8524269
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Mammalian target of rapamycin-dependent acinar cell neoplasia after inactivation of Apc and Pten in the mouse salivary gland: implications for human acinic cell carcinoma.
    Diegel CR; Cho KR; El-Naggar AK; Williams BO; Lindvall C
    Cancer Res; 2010 Nov; 70(22):9143-52. PubMed ID: 21062985
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.
    Callén E; Bunting S; Huang CY; Difilippantonio MJ; Wong N; Khor B; Mahowald G; Kruhlak MJ; Ried T; Sleckman BP; Nussenzweig A
    Cell Cycle; 2009 Aug; 8(15):2408-12. PubMed ID: 19556863
    [TBL] [Abstract][Full Text] [Related]  

  • 46. AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradation.
    Vartanian R; Masri J; Martin J; Cloninger C; Holmes B; Artinian N; Funk A; Ruegg T; Gera J
    Mol Cancer Res; 2011 Jan; 9(1):115-30. PubMed ID: 21135252
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors.
    Blom B; Heemskerk MH; Verschuren MC; van Dongen JJ; Stegmann AP; Bakker AQ; Couwenberg F; Res PC; Spits H
    EMBO J; 1999 May; 18(10):2793-802. PubMed ID: 10329625
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Acquired expression of osteopontin selectively promotes enrichment of leukemia stem cells through AKT/mTOR/PTEN/β-catenin pathways in AML cells.
    Mohammadi S; Ghaffari SH; Shaiegan M; Zarif MN; Nikbakht M; Akbari Birgani S; Alimoghadam K; Ghavamzadeh A
    Life Sci; 2016 May; 152():190-8. PubMed ID: 27063991
    [TBL] [Abstract][Full Text] [Related]  

  • 49. c-Myc controls the development of CD8alphaalpha TCRalphabeta intestinal intraepithelial lymphocytes from thymic precursors by regulating IL-15-dependent survival.
    Jiang W; Ferrero I; Laurenti E; Trumpp A; MacDonald HR
    Blood; 2010 Jun; 115(22):4431-8. PubMed ID: 20308599
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Cutting Edge: CD3 ITAM Diversity Is Required for Optimal TCR Signaling and Thymocyte Development.
    Bettini ML; Chou PC; Guy CS; Lee T; Vignali KM; Vignali DAA
    J Immunol; 2017 Sep; 199(5):1555-1560. PubMed ID: 28733484
    [TBL] [Abstract][Full Text] [Related]  

  • 51. A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.
    Herranz D; Ambesi-Impiombato A; Palomero T; Schnell SA; Belver L; Wendorff AA; Xu L; Castillo-Martin M; Llobet-Navás D; Cordon-Cardo C; Clappier E; Soulier J; Ferrando AA
    Nat Med; 2014 Oct; 20(10):1130-7. PubMed ID: 25194570
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Early TCRalpha expression generates TCRalphagamma complexes that signal the DN-to-DP transition and impair development.
    Erman B; Feigenbaum L; Coligan JE; Singer A
    Nat Immunol; 2002 Jun; 3(6):564-9. PubMed ID: 12021779
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia.
    Gutierrez A; Grebliunaite R; Feng H; Kozakewich E; Zhu S; Guo F; Payne E; Mansour M; Dahlberg SE; Neuberg DS; den Hertog J; Prochownik EV; Testa JR; Harris M; Kanki JP; Look AT
    J Exp Med; 2011 Aug; 208(8):1595-603. PubMed ID: 21727187
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Developmental regulation of V(D)J recombination at the TCR alpha/delta locus.
    Krangel MS; Hernandez-Munain C; Lauzurica P; McMurry M; Roberts JL; Zhong XP
    Immunol Rev; 1998 Oct; 165():131-47. PubMed ID: 9850858
    [TBL] [Abstract][Full Text] [Related]  

  • 55. c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.
    Roderick JE; Tesell J; Shultz LD; Brehm MA; Greiner DL; Harris MH; Silverman LB; Sallan SE; Gutierrez A; Look AT; Qi J; Bradner JE; Kelliher MA
    Blood; 2014 Feb; 123(7):1040-50. PubMed ID: 24394663
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Unexpectedly late expression of intracellular CD3epsilon and TCR gammadelta proteins during adult thymus development.
    Wilson A; Capone M; MacDonald HR
    Int Immunol; 1999 Oct; 11(10):1641-50. PubMed ID: 10508182
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Costimulation-dependent expression of microRNA-214 increases the ability of T cells to proliferate by targeting Pten.
    Jindra PT; Bagley J; Godwin JG; Iacomini J
    J Immunol; 2010 Jul; 185(2):990-7. PubMed ID: 20548023
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Translocation t(8;14)(q24;q11) with concurrent PTEN alterations and deletions of STIL/TAL1 and CDKN2A/B in a pediatric case of acute T-lymphoblastic leukemia: A genetic profile associated with adverse prognosis.
    Skalska-Sadowska J; Dawidowska M; Szarzyńska-Zawadzka B; Jarmuż-Szymczak M; Czerwińska-Rybak J; Machowska L; Derwich K
    Pediatr Blood Cancer; 2017 Apr; 64(4):. PubMed ID: 27759908
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells.
    Blank C; Brown I; Marks R; Nishimura H; Honjo T; Gajewski TF
    J Immunol; 2003 Nov; 171(9):4574-81. PubMed ID: 14568931
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.
    Tan Q; Brunetti L; Rousseaux MWC; Lu HC; Wan YW; Revelli JP; Liu Z; Goodell MA; Zoghbi HY
    Proc Natl Acad Sci U S A; 2018 Feb; 115(7):E1511-E1519. PubMed ID: 29382756
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.