112 related articles for article (PubMed ID: 21212517)
1. Role of FGD1, a Cdc42 guanine nucleotide exchange factor, in epidermal growth factor-stimulated c-Jun NH2-terminal kinase activation and cell migration.
Oshima T; Fujino T; Ando K; Hayakawa M
Biol Pharm Bull; 2011; 34(1):54-60. PubMed ID: 21212517
[TBL] [Abstract][Full Text] [Related]
2. Proline-rich domain plays a crucial role in extracellular stimuli-responsive translocation of a Cdc42 guanine nucleotide exchange factor, FGD1.
Oshima T; Fujino T; Ando K; Hayakawa M
Biol Pharm Bull; 2010; 33(1):35-9. PubMed ID: 20045932
[TBL] [Abstract][Full Text] [Related]
3. Novel insights into FGD3, a putative GEF for Cdc42, that undergoes SCF(FWD1/beta-TrCP)-mediated proteasomal degradation analogous to that of its homologue FGD1 but regulates cell morphology and motility differently from FGD1.
Hayakawa M; Matsushima M; Hagiwara H; Oshima T; Fujino T; Ando K; Kikugawa K; Tanaka H; Miyazawa K; Kitagawa M
Genes Cells; 2008 Apr; 13(4):329-42. PubMed ID: 18363964
[TBL] [Abstract][Full Text] [Related]
4. Isolation, characterization, and mapping of the mouse Fgd3 gene, a new Faciogenital Dysplasia (FGD1; Aarskog Syndrome) gene homologue.
Pasteris NG; Nagata K; Hall A; Gorski JL
Gene; 2000 Jan; 242(1-2):237-47. PubMed ID: 10721717
[TBL] [Abstract][Full Text] [Related]
5. Activation of G1 progression, JNK mitogen-activated protein kinase, and actin filament assembly by the exchange factor FGD1.
Nagata K; Driessens M; Lamarche N; Gorski JL; Hall A
J Biol Chem; 1998 Jun; 273(25):15453-7. PubMed ID: 9624130
[TBL] [Abstract][Full Text] [Related]
6. The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor.
Zheng Y; Fischer DJ; Santos MF; Tigyi G; Pasteris NG; Gorski JL; Xu Y
J Biol Chem; 1996 Dec; 271(52):33169-72. PubMed ID: 8969170
[TBL] [Abstract][Full Text] [Related]
7. Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases.
Olson MF; Pasteris NG; Gorski JL; Hall A
Curr Biol; 1996 Dec; 6(12):1628-33. PubMed ID: 8994827
[TBL] [Abstract][Full Text] [Related]
8. Fgd1, the Cdc42 guanine nucleotide exchange factor responsible for faciogenital dysplasia, is localized to the subcortical actin cytoskeleton and Golgi membrane.
Estrada L; Caron E; Gorski JL
Hum Mol Genet; 2001 Mar; 10(5):485-95. PubMed ID: 11181572
[TBL] [Abstract][Full Text] [Related]
9. A mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome).
Orrico A; Galli L; Falciani M; Bracci M; Cavaliere ML; Rinaldi MM; Musacchio A; Sorrentino V
FEBS Lett; 2000 Aug; 478(3):216-20. PubMed ID: 10930571
[TBL] [Abstract][Full Text] [Related]
10. Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.
Michiels F; Stam JC; Hordijk PL; van der Kammen RA; Ruuls-Van Stalle L; Feltkamp CA; Collard JG
J Cell Biol; 1997 Apr; 137(2):387-98. PubMed ID: 9128250
[TBL] [Abstract][Full Text] [Related]
11. Unilateral focal polymicrogyria in a patient with classical Aarskog-Scott syndrome due to a novel missense mutation in an evolutionary conserved RhoGEF domain of the faciogenital dysplasia gene FGD1.
Bottani A; Orrico A; Galli L; Karam O; Haenggeli CA; Ferey S; Conrad B
Am J Med Genet A; 2007 Oct; 143A(19):2334-8. PubMed ID: 17847065
[TBL] [Abstract][Full Text] [Related]
12. The Aarskog-Scott syndrome protein Fgd1 regulates podosome formation and extracellular matrix remodeling in transforming growth factor β-stimulated aortic endothelial cells.
Daubon T; Buccione R; Génot E
Mol Cell Biol; 2011 Nov; 31(22):4430-41. PubMed ID: 21911474
[TBL] [Abstract][Full Text] [Related]
13. Signal-crosstalk between Rho/ROCK and c-Jun NH2-terminal kinase mediates migration of vascular smooth muscle cells stimulated by angiotensin II.
Ohtsu H; Mifune M; Frank GD; Saito S; Inagami T; Kim-Mitsuyama S; Takuwa Y; Sasaki T; Rothstein JD; Suzuki H; Nakashima H; Woolfolk EA; Motley ED; Eguchi S
Arterioscler Thromb Vasc Biol; 2005 Sep; 25(9):1831-6. PubMed ID: 15994438
[TBL] [Abstract][Full Text] [Related]
14. Genomic organization of the faciogenital dysplasia (FGD1; Aarskog syndrome) gene.
Pasteris NG; Buckler J; Cadle AB; Gorski JL
Genomics; 1997 Aug; 43(3):390-4. PubMed ID: 9268645
[TBL] [Abstract][Full Text] [Related]
15. Oligomerization of DH domain is essential for Dbl-induced transformation.
Zhu K; Debreceni B; Bi F; Zheng Y
Mol Cell Biol; 2001 Jan; 21(2):425-37. PubMed ID: 11134331
[TBL] [Abstract][Full Text] [Related]
16. Minireview: Role of genetic changes of faciogenital dysplasia protein 1 in human disease.
Pedigo NG; Van Delden D; Walters L; Farrell CL
Physiol Genomics; 2016 Jul; 48(7):446-54. PubMed ID: 27199457
[TBL] [Abstract][Full Text] [Related]
17. FGD1-related Aarskog-Scott syndrome: Identification of four novel variations and a literature review of clinical and molecular aspects.
Li S; Tian A; Wen Y; Gu W; Li W; Qiao X; Zhang C; Luo X
Eur J Pediatr; 2024 May; 183(5):2257-2272. PubMed ID: 38411716
[TBL] [Abstract][Full Text] [Related]
18. The FWD1/beta-TrCP-mediated degradation pathway establishes a 'turning off switch' of a Cdc42 guanine nucleotide exchange factor, FGD1.
Hayakawa M; Kitagawa H; Miyazawa K; Kitagawa M; Kikugawa K
Genes Cells; 2005 Mar; 10(3):241-51. PubMed ID: 15743413
[TBL] [Abstract][Full Text] [Related]
19. Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase.
Obaishi H; Nakanishi H; Mandai K; Satoh K; Satoh A; Takahashi K; Miyahara M; Nishioka H; Takaishi K; Takai Y
J Biol Chem; 1998 Jul; 273(30):18697-700. PubMed ID: 9668039
[TBL] [Abstract][Full Text] [Related]
20. CDC42 and FGD1 cause distinct signaling and transforming activities.
Whitehead IP; Abe K; Gorski JL; Der CJ
Mol Cell Biol; 1998 Aug; 18(8):4689-97. PubMed ID: 9671479
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]