These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

474 related articles for article (PubMed ID: 21213095)

  • 1. Anesthetic sites and allosteric mechanisms of action on Cys-loop ligand-gated ion channels.
    Forman SA; Miller KW
    Can J Anaesth; 2011 Feb; 58(2):191-205. PubMed ID: 21213095
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GABA(A) receptors as molecular targets of general anesthetics: identification of binding sites provides clues to allosteric modulation.
    Olsen RW; Li GD
    Can J Anaesth; 2011 Feb; 58(2):206-15. PubMed ID: 21194017
    [TBL] [Abstract][Full Text] [Related]  

  • 3. p-Trifluoromethyldiazirinyl-etomidate: a potent photoreactive general anesthetic derivative of etomidate that is selective for ligand-gated cationic ion channels.
    Husain SS; Stewart D; Desai R; Hamouda AK; Li SG; Kelly E; Dostalova Z; Zhou X; Cotten JF; Raines DE; Olsen RW; Cohen JB; Forman SA; Miller KW
    J Med Chem; 2010 Sep; 53(17):6432-44. PubMed ID: 20704351
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multiple transmembrane binding sites for p-trifluoromethyldiazirinyl-etomidate, a photoreactive Torpedo nicotinic acetylcholine receptor allosteric inhibitor.
    Hamouda AK; Stewart DS; Husain SS; Cohen JB
    J Biol Chem; 2011 Jun; 286(23):20466-77. PubMed ID: 21498509
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of trifluoromethylaryl diazirine and benzophenone derivatives of etomidate that are potent general anesthetics and effective photolabels for probing sites on ligand-gated ion channels.
    Husain SS; Nirthanan S; Ruesch D; Solt K; Cheng Q; Li GD; Arevalo E; Olsen RW; Raines DE; Forman SA; Cohen JB; Miller KW
    J Med Chem; 2006 Aug; 49(16):4818-25. PubMed ID: 16884293
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tryptophan mutations at azi-etomidate photo-incorporation sites on alpha1 or beta2 subunits enhance GABAA receptor gating and reduce etomidate modulation.
    Stewart D; Desai R; Cheng Q; Liu A; Forman SA
    Mol Pharmacol; 2008 Dec; 74(6):1687-95. PubMed ID: 18805938
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels.
    Husain SS; Ziebell MR; Ruesch D; Hong F; Arevalo E; Kosterlitz JA; Olsen RW; Forman SA; Cohen JB; Miller KW
    J Med Chem; 2003 Mar; 46(7):1257-65. PubMed ID: 12646036
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor.
    Chiara DC; Jayakar SS; Zhou X; Zhang X; Savechenkov PY; Bruzik KS; Miller KW; Cohen JB
    J Biol Chem; 2013 Jul; 288(27):19343-57. PubMed ID: 23677991
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A potent photoreactive general anesthetic with novel binding site selectivity for GABA
    Shalabi AR; Yu Z; Zhou X; Jounaidi Y; Chen H; Dai J; Kent DE; Feng HJ; Forman SA; Cohen JB; Bruzik KS; Miller KW
    Eur J Med Chem; 2020 May; 194():112261. PubMed ID: 32247113
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neurosteroids allosterically modulate binding of the anesthetic etomidate to gamma-aminobutyric acid type A receptors.
    Li GD; Chiara DC; Cohen JB; Olsen RW
    J Biol Chem; 2009 May; 284(18):11771-5. PubMed ID: 19282280
    [TBL] [Abstract][Full Text] [Related]  

  • 11. State-dependent etomidate occupancy of its allosteric agonist sites measured in a cysteine-substituted GABAA receptor.
    Stewart DS; Hotta M; Desai R; Forman SA
    Mol Pharmacol; 2013 Jun; 83(6):1200-8. PubMed ID: 23525330
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Allosteric ligands and their binding sites define γ-aminobutyric acid (GABA) type A receptor subtypes.
    Olsen RW
    Adv Pharmacol; 2015; 73():167-202. PubMed ID: 25637441
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Etomidate produces similar allosteric modulation in α1β3δ and α1β3γ2L GABA(A) receptors.
    Feng HJ; Jounaidi Y; Haburcak M; Yang X; Forman SA
    Br J Pharmacol; 2014 Feb; 171(3):789-98. PubMed ID: 24199598
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Numerous classes of general anesthetics inhibit etomidate binding to gamma-aminobutyric acid type A (GABAA) receptors.
    Li GD; Chiara DC; Cohen JB; Olsen RW
    J Biol Chem; 2010 Mar; 285(12):8615-20. PubMed ID: 20083606
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of binding sites in the nicotinic acetylcholine receptor for TDBzl-etomidate, a photoreactive positive allosteric effector.
    Nirthanan S; Garcia G; Chiara DC; Husain SS; Cohen JB
    J Biol Chem; 2008 Aug; 283(32):22051-62. PubMed ID: 18524766
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics.
    Carlson BX; Engblom AC; Kristiansen U; Schousboe A; Olsen RW
    Mol Pharmacol; 2000 Mar; 57(3):474-84. PubMed ID: 10692487
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue.
    Chiara DC; Dostalova Z; Jayakar SS; Zhou X; Miller KW; Cohen JB
    Biochemistry; 2012 Jan; 51(4):836-47. PubMed ID: 22243422
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural interplay of anesthetics and paralytics on muscle nicotinic receptors.
    Goswami U; Rahman MM; Teng J; Hibbs RE
    Nat Commun; 2023 Jun; 14(1):3169. PubMed ID: 37264005
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enantiomeric barbiturates bind distinct inter- and intrasubunit binding sites in a nicotinic acetylcholine receptor (nAChR).
    Yu Z; Cohen JB
    J Biol Chem; 2017 Oct; 292(42):17258-17271. PubMed ID: 28878016
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cysteine substitutions define etomidate binding and gating linkages in the α-M1 domain of γ-aminobutyric acid type A (GABAA) receptors.
    Stewart DS; Hotta M; Li GD; Desai R; Chiara DC; Olsen RW; Forman SA
    J Biol Chem; 2013 Oct; 288(42):30373-30386. PubMed ID: 24009076
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.