403 related articles for article (PubMed ID: 2121335)
1. Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells.
Siegel D; Gibson NW; Preusch PC; Ross D
Cancer Res; 1990 Nov; 50(22):7293-300. PubMed ID: 2121335
[TBL] [Abstract][Full Text] [Related]
2. Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells.
Siegel D; Gibson NW; Preusch PC; Ross D
Cancer Res; 1990 Dec; 50(23):7483-9. PubMed ID: 1701346
[TBL] [Abstract][Full Text] [Related]
3. Relationship between DT-diaphorase-mediated metabolism of a series of aziridinylbenzoquinones and DNA damage and cytotoxicity.
Gibson NW; Hartley JA; Butler J; Siegel D; Ross D
Mol Pharmacol; 1992 Sep; 42(3):531-6. PubMed ID: 1406604
[TBL] [Abstract][Full Text] [Related]
4. The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
Qiu XB; Cadenas E
Arch Biochem Biophys; 1997 Oct; 346(2):241-51. PubMed ID: 9343371
[TBL] [Abstract][Full Text] [Related]
5. The reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells: free radical formation and NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase) activity.
Fisher GR; Gutierrez PL
Free Radic Biol Med; 1991; 10(6):359-70. PubMed ID: 1654286
[TBL] [Abstract][Full Text] [Related]
6. Activation and deactivation of quinones catalyzed by DT-diaphorase. Evidence for bioreductive activation of diaziquone (AZQ) in human tumor cells and detoxification of benzene metabolites in bone marrow stroma.
Ross D; Siegel D; Gibson NW; Pacheco D; Thomas DJ; Reasor M; Wierda D
Free Radic Res Commun; 1990; 8(4-6):373-81. PubMed ID: 2113030
[TBL] [Abstract][Full Text] [Related]
7. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
Fourie J; Oleschuk CJ; Guziec F; Guziec L; Fiterman DJ; Monterrosa C; Begleiter A
Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423
[TBL] [Abstract][Full Text] [Related]
8. Thiol oxidation coupled to DT-diaphorase-catalysed reduction of diaziquone. Reductive and oxidative pathways of diaziquone semiquinone modulated by glutathione and superoxide dismutase.
Ordoñez ID; Cadenas E
Biochem J; 1992 Sep; 286 ( Pt 2)(Pt 2):481-90. PubMed ID: 1530580
[TBL] [Abstract][Full Text] [Related]
9. Reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells. II. Enhancement of the alkylating activity of AZQ by NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase).
Fisher GR; Donis J; Gutierrez PL
Biochem Pharmacol; 1992 Oct; 44(8):1625-35. PubMed ID: 1301071
[TBL] [Abstract][Full Text] [Related]
10. Structure-activity relationships for DT-diaphorase reduction of hypoxic cell directed agents: indoloquinones and diaziridinyl benzoquinones.
Bailey SM; Suggett N; Walton MI; Workman P
Int J Radiat Oncol Biol Phys; 1992; 22(4):649-53. PubMed ID: 1544832
[TBL] [Abstract][Full Text] [Related]
11. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases.
Beall HD; Mulcahy RT; Siegel D; Traver RD; Gibson NW; Ross D
Cancer Res; 1994 Jun; 54(12):3196-201. PubMed ID: 8205540
[TBL] [Abstract][Full Text] [Related]
12. Free radical formation and DNA strand breakage during metabolism of diaziquone by NAD(P)H quinone-acceptor oxidoreductase (DT-diaphorase) and NADPH cytochrome c reductase.
Fisher GR; Gutierrez PL
Free Radic Biol Med; 1991; 11(6):597-607. PubMed ID: 1663902
[TBL] [Abstract][Full Text] [Related]
13. Modulation of trenimon-induced cytotoxicity by DT-diaphorase in isolated rat hepatocytes under aerobic versus hypoxic conditions.
Silva JM; Rao DN; O'Brien PJ
Cancer Res; 1992 Jun; 52(11):3015-21. PubMed ID: 1375532
[TBL] [Abstract][Full Text] [Related]
14. Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase.
Wu K; Knox R; Sun XZ; Joseph P; Jaiswal AK; Zhang D; Deng PS; Chen S
Arch Biochem Biophys; 1997 Nov; 347(2):221-8. PubMed ID: 9367528
[TBL] [Abstract][Full Text] [Related]
15. The role of NAD(P)H: quinone reductase (EC 1.6.99.2, DT-diaphorase) in the reductive bioactivation of the novel indoloquinone antitumor agent EO9.
Walton MI; Smith PJ; Workman P
Cancer Commun; 1991 Jul; 3(7):199-206. PubMed ID: 1714284
[TBL] [Abstract][Full Text] [Related]
16. A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent.
Winski SL; Hargreaves RH; Butler J; Ross D
Clin Cancer Res; 1998 Dec; 4(12):3083-8. PubMed ID: 9865924
[TBL] [Abstract][Full Text] [Related]
17. Cytotoxic mechanisms of anti-tumour quinones in parental and resistant lymphoblasts.
Halinska A; Belej T; O'Brien PJ
Br J Cancer Suppl; 1996 Jul; 27():S23-7. PubMed ID: 8763840
[TBL] [Abstract][Full Text] [Related]
18. pH-dependent inactivation of DT-diaphorase by mitomycin C and porfiromycin.
Siegel D; Beall H; Kasai M; Arai H; Gibson NW; Ross D
Mol Pharmacol; 1993 Dec; 44(6):1128-34. PubMed ID: 8264549
[TBL] [Abstract][Full Text] [Related]
19. Structure-activity study with bioreductive benzoquinone alkylating agents: effects on DT-diaphorase-mediated DNA crosslink and strand break formation in relation to mechanisms of cytotoxicity.
Fourie J; Guziec F; Guziec L; Monterrosa C; Fiterman DJ; Begleiter A
Cancer Chemother Pharmacol; 2004 Mar; 53(3):191-203. PubMed ID: 14614574
[TBL] [Abstract][Full Text] [Related]
20. Diaziquone-induced cytotoxicity in isolated rat hepatocytes.
Silva JM; O'Brien PJ
Cancer Res; 1989 Oct; 49(20):5550-4. PubMed ID: 2790779
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
