These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. SIH--a novel lipophilic iron chelator--protects H9c2 cardiomyoblasts from oxidative stress-induced mitochondrial injury and cell death. Simůnek T; Boer C; Bouwman RA; Vlasblom R; Versteilen AM; Sterba M; Gersl V; Hrdina R; Ponka P; de Lange JJ; Paulus WJ; Musters RJ J Mol Cell Cardiol; 2005 Aug; 39(2):345-54. PubMed ID: 15978614 [TBL] [Abstract][Full Text] [Related]
5. 2,6-Dihydroxybenzaldehyde Analogues of the Iron Chelator Salicylaldehyde Isonicotinoyl Hydrazone: Increased Hydrolytic Stability and Cytoprotective Activity against Oxidative Stress. Jansová H; Kubeš J; Reimerová P; Štěrbová-Kovaříková P; Roh J; Šimůnek T Chem Res Toxicol; 2018 Nov; 31(11):1151-1163. PubMed ID: 30395451 [TBL] [Abstract][Full Text] [Related]
6. Iron chelation-afforded cardioprotection against chronic anthracycline cardiotoxicity: a study of salicylaldehyde isonicotinoyl hydrazone (SIH). Sterba M; Popelová O; Simůnek T; Mazurová Y; Potácová A; Adamcová M; Guncová I; Kaiserová H; Palicka V; Ponka P; Gersl V Toxicology; 2007 Jun; 235(3):150-66. PubMed ID: 17459556 [TBL] [Abstract][Full Text] [Related]
7. Iron chelation with salicylaldehyde isonicotinoyl hydrazone protects against catecholamine autoxidation and cardiotoxicity. Hašková P; Kovaříková P; Koubková L; Vávrová A; Macková E; Simůnek T Free Radic Biol Med; 2011 Feb; 50(4):537-49. PubMed ID: 21147217 [TBL] [Abstract][Full Text] [Related]
8. Investigation of the stability of aromatic hydrazones in plasma and related biological material. Kovaríková P; Mrkvicková Z; Klimes J J Pharm Biomed Anal; 2008 Jun; 47(2):360-70. PubMed ID: 18294799 [TBL] [Abstract][Full Text] [Related]
9. Prooxidant and antioxidant properties of salicylaldehyde isonicotinoyl hydrazone iron chelators in HepG2 cells. Caro AA; Commissariat A; Dunn C; Kim H; García SL; Smith A; Strang H; Stuppy J; Desrochers LP; Goodwin TE Biochim Biophys Acta; 2015 Nov; 1850(11):2256-64. PubMed ID: 26275495 [TBL] [Abstract][Full Text] [Related]
10. Structure-Activity Relationships of Nitro-Substituted Aroylhydrazone Iron Chelators with Antioxidant and Antiproliferative Activities. Hrušková K; Potůčková E; Opálka L; Hergeselová T; Hašková P; Kovaříková P; Šimůnek T; Vávrová K Chem Res Toxicol; 2018 Jun; 31(6):435-446. PubMed ID: 29766723 [TBL] [Abstract][Full Text] [Related]
11. Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products. Jansová H; Bureš J; Macháček M; Hašková P; Jirkovská A; Roh J; Wang Q; Franz KJ; Kovaříková P; Šimůnek T Toxicology; 2016 Mar; 350-352():15-24. PubMed ID: 27046792 [TBL] [Abstract][Full Text] [Related]
12. Aroylhydrazone iron chelators: Tuning antioxidant and antiproliferative properties by hydrazide modifications. Hrušková K; Potůčková E; Hergeselová T; Liptáková L; Hašková P; Mingas P; Kovaříková P; Šimůnek T; Vávrová K Eur J Med Chem; 2016 Sep; 120():97-110. PubMed ID: 27187862 [TBL] [Abstract][Full Text] [Related]
13. Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury. Jansová H; Macháček M; Wang Q; Hašková P; Jirkovská A; Potůčková E; Kielar F; Franz KJ; Simůnek T Free Radic Biol Med; 2014 Sep; 74():210-21. PubMed ID: 24992833 [TBL] [Abstract][Full Text] [Related]
14. LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH). Bureš J; Jansová H; Stariat J; Filipský T; Mladěnka P; Šimůnek T; Kučera R; Klimeš J; Wang Q; Franz KJ; Kovaříková P J Pharm Biomed Anal; 2015 Feb; 105():55-63. PubMed ID: 25527982 [TBL] [Abstract][Full Text] [Related]
15. Iron chelators: correlation between effects on Plasmodium spp. and immune functions. Golenser J; Domb A; Mordechai-Daniel T; Leshem B; Luty A; Kremsner P J Parasitol; 2006 Feb; 92(1):170-7. PubMed ID: 16629332 [TBL] [Abstract][Full Text] [Related]
16. Variable inhibitory effects on the formation of dinitrosyl iron complexes by deferoxamine and salicylaldehyde isonicotinoyl hydrazone in K562 cells. Meczynska S; Lewandowska H; Sochanowicz B; Sadlo J; Kruszewski M Hemoglobin; 2008; 32(1-2):157-63. PubMed ID: 18274993 [TBL] [Abstract][Full Text] [Related]
17. Iron is not involved in oxidative stress-mediated cytotoxicity of doxorubicin and bleomycin. Kaiserová H; den Hartog GJ; Simůnek T; Schröterová L; Kvasnicková E; Bast A Br J Pharmacol; 2006 Dec; 149(7):920-30. PubMed ID: 17031387 [TBL] [Abstract][Full Text] [Related]
18. Protection against hydrogen peroxide-mediated cytotoxicity in Friedreich's ataxia fibroblasts using novel iron chelators of the 2-pyridylcarboxaldehyde isonicotinoyl hydrazone class. Lim CK; Kalinowski DS; Richardson DR Mol Pharmacol; 2008 Jul; 74(1):225-35. PubMed ID: 18424550 [TBL] [Abstract][Full Text] [Related]
19. Intralysosomal iron chelation protects against oxidative stress-induced cellular damage. Kurz T; Gustafsson B; Brunk UT FEBS J; 2006 Jul; 273(13):3106-17. PubMed ID: 16762036 [TBL] [Abstract][Full Text] [Related]
20. Comparison of clinically used and experimental iron chelators for protection against oxidative stress-induced cellular injury. Bendova P; Mackova E; Haskova P; Vavrova A; Jirkovsky E; Sterba M; Popelova O; Kalinowski DS; Kovarikova P; Vavrova K; Richardson DR; Simunek T Chem Res Toxicol; 2010 Jun; 23(6):1105-14. PubMed ID: 20521781 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]