These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in multiple myeloma cells through transcriptional repression and down-regulation of Mcl-1. Gojo I; Zhang B; Fenton RG Clin Cancer Res; 2002 Nov; 8(11):3527-38. PubMed ID: 12429644 [TBL] [Abstract][Full Text] [Related]
3. Preclinical activity of P276-00, a novel small-molecule cyclin-dependent kinase inhibitor in the therapy of multiple myeloma. Raje N; Hideshima T; Mukherjee S; Raab M; Vallet S; Chhetri S; Cirstea D; Pozzi S; Mitsiades C; Rooney M; Kiziltepe T; Podar K; Okawa Y; Ikeda H; Carrasco R; Richardson PG; Chauhan D; Munshi NC; Sharma S; Parikh H; Chabner B; Scadden D; Anderson KC Leukemia; 2009 May; 23(5):961-70. PubMed ID: 19151776 [TBL] [Abstract][Full Text] [Related]
4. Potentiation of anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the cyclin-dependent kinase inhibitor P276-00 in human non-small-cell lung cancer cell lines. Shirsath N; Rathos M; Chaudhari U; Sivaramakrishnan H; Joshi K Lung Cancer; 2013 Nov; 82(2):214-21. PubMed ID: 24051085 [TBL] [Abstract][Full Text] [Related]
5. P276-00, a cyclin-dependent kinase inhibitor, modulates cell cycle and induces apoptosis in vitro and in vivo in mantle cell lymphoma cell lines. Shirsath NP; Manohar SM; Joshi KS Mol Cancer; 2012 Oct; 11():77. PubMed ID: 23075291 [TBL] [Abstract][Full Text] [Related]
6. Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1. MacCallum DE; Melville J; Frame S; Watt K; Anderson S; Gianella-Borradori A; Lane DP; Green SR Cancer Res; 2005 Jun; 65(12):5399-407. PubMed ID: 15958589 [TBL] [Abstract][Full Text] [Related]
7. Cyclin-dependent kinase inhibitor, P276-00, inhibits HIF-1α and induces G2/M arrest under hypoxia in prostate cancer cells. Manohar SM; Padgaonkar AA; Jalota-Badhwar A; Rao SV; Joshi KS Prostate Cancer Prostatic Dis; 2012 Mar; 15(1):15-27. PubMed ID: 22083267 [TBL] [Abstract][Full Text] [Related]
8. Arylazopyrazole AAP1742 inhibits CDKs and induces apoptosis in multiple myeloma cells via Mcl-1 downregulation. Jorda R; Navrátilová J; Hušková Z; Schütznerová E; Cankař P; Strnad M; Kryštof V Chem Biol Drug Des; 2014 Oct; 84(4):402-8. PubMed ID: 24803299 [TBL] [Abstract][Full Text] [Related]
9. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors. Pei XY; Dai Y; Grant S Clin Cancer Res; 2004 Jun; 10(11):3839-52. PubMed ID: 15173093 [TBL] [Abstract][Full Text] [Related]
10. Potent antimyeloma activity of a novel ERK5/CDK inhibitor. Álvarez-Fernández S; Ortiz-Ruiz MJ; Parrott T; Zaknoen S; Ocio EM; San Miguel J; Burrows FJ; Esparís-Ogando A; Pandiella A Clin Cancer Res; 2013 May; 19(10):2677-87. PubMed ID: 23532886 [TBL] [Abstract][Full Text] [Related]
11. Induction of apoptosis and cell cycle arrest by a chalcone panduratin A isolated from Kaempferia pandurata in androgen-independent human prostate cancer cells PC3 and DU145. Yun JM; Kweon MH; Kwon H; Hwang JK; Mukhtar H Carcinogenesis; 2006 Jul; 27(7):1454-64. PubMed ID: 16497706 [TBL] [Abstract][Full Text] [Related]
12. In vitro antitumor properties of a novel cyclin-dependent kinase inhibitor, P276-00. Joshi KS; Rathos MJ; Joshi RD; Sivakumar M; Mascarenhas M; Kamble S; Lal B; Sharma S Mol Cancer Ther; 2007 Mar; 6(3):918-25. PubMed ID: 17363486 [TBL] [Abstract][Full Text] [Related]
13. Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor, ENMD-2076, against multiple myeloma. Wang X; Sinn AL; Pollok K; Sandusky G; Zhang S; Chen L; Liang J; Crean CD; Suvannasankha A; Abonour R; Sidor C; Bray MR; Farag SS Br J Haematol; 2010 Aug; 150(3):313-25. PubMed ID: 20560971 [TBL] [Abstract][Full Text] [Related]
14. P276-00, a novel cyclin-dependent inhibitor induces G1-G2 arrest, shows antitumor activity on cisplatin-resistant cells and significant in vivo efficacy in tumor models. Joshi KS; Rathos MJ; Mahajan P; Wagh V; Shenoy S; Bhatia D; Chile S; Sivakumar M; Maier A; Fiebig HH; Sharma S Mol Cancer Ther; 2007 Mar; 6(3):926-34. PubMed ID: 17363487 [TBL] [Abstract][Full Text] [Related]
15. The PI3K inhibitor GDC-0941 combines with existing clinical regimens for superior activity in multiple myeloma. Munugalavadla V; Mariathasan S; Slaga D; Du C; Berry L; Del Rosario G; Yan Y; Boe M; Sun L; Friedman LS; Chesi M; Leif Bergsagel P; Ebens A Oncogene; 2014 Jan; 33(3):316-25. PubMed ID: 23318440 [TBL] [Abstract][Full Text] [Related]
16. Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. Agarwal C; Singh RP; Dhanalakshmi S; Tyagi AK; Tecklenburg M; Sclafani RA; Agarwal R Oncogene; 2003 Nov; 22(51):8271-82. PubMed ID: 14614451 [TBL] [Abstract][Full Text] [Related]
17. Triptolide inhibits Bcr-Abl transcription and induces apoptosis in STI571-resistant chronic myelogenous leukemia cells harboring T315I mutation. Shi X; Jin Y; Cheng C; Zhang H; Zou W; Zheng Q; Lu Z; Chen Q; Lai Y; Pan J Clin Cancer Res; 2009 Mar; 15(5):1686-97. PubMed ID: 19240172 [TBL] [Abstract][Full Text] [Related]
18. Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis. Park WH; Seol JG; Kim ES; Hyun JM; Jung CW; Lee CC; Kim BK; Lee YY Cancer Res; 2000 Jun; 60(11):3065-71. PubMed ID: 10850458 [TBL] [Abstract][Full Text] [Related]
19. Improvement of esophageal adenocarcinoma cell and xenograft responses to radiation by targeting cyclin-dependent kinases. Raju U; Ariga H; Koto M; Lu X; Pickett J; Valdecanas D; Mason KA; Milas L Radiother Oncol; 2006 Aug; 80(2):185-91. PubMed ID: 16905211 [TBL] [Abstract][Full Text] [Related]
20. Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells. Ahn MY; Lee J; Na YJ; Choi WS; Lee BM; Kang KW; Kim HS Chem Biol Interact; 2009 May; 179(2-3):169-77. PubMed ID: 19070610 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]