197 related articles for article (PubMed ID: 21223987)
1. Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice.
Beyerle A; Braun A; Merkel O; Koch F; Kissel T; Stoeger T
J Control Release; 2011 Apr; 151(1):51-6. PubMed ID: 21223987
[TBL] [Abstract][Full Text] [Related]
2. Nonviral siRNA delivery to the lung: investigation of PEG-PEI polyplexes and their in vivo performance.
Merkel OM; Beyerle A; Librizzi D; Pfestroff A; Behr TM; Sproat B; Barth PJ; Kissel T
Mol Pharm; 2009; 6(4):1246-60. PubMed ID: 19606864
[TBL] [Abstract][Full Text] [Related]
3. Inflammatory responses to pulmonary application of PEI-based siRNA nanocarriers in mice.
Beyerle A; Braun A; Banerjee A; Ercal N; Eickelberg O; Kissel TH; Stoeger T
Biomaterials; 2011 Nov; 32(33):8694-701. PubMed ID: 21855131
[TBL] [Abstract][Full Text] [Related]
4. Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes.
Mao S; Neu M; Germershaus O; Merkel O; Sitterberg J; Bakowsky U; Kissel T
Bioconjug Chem; 2006; 17(5):1209-18. PubMed ID: 16984130
[TBL] [Abstract][Full Text] [Related]
5. In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes.
Malek A; Merkel O; Fink L; Czubayko F; Kissel T; Aigner A
Toxicol Appl Pharmacol; 2009 Apr; 236(1):97-108. PubMed ID: 19371615
[TBL] [Abstract][Full Text] [Related]
6. PEGylation of poly(ethylene imine) affects stability of complexes with plasmid DNA under in vivo conditions in a dose-dependent manner after intravenous injection into mice.
Merdan T; Kunath K; Petersen H; Bakowsky U; Voigt KH; Kopecek J; Kissel T
Bioconjug Chem; 2005; 16(4):785-92. PubMed ID: 16029019
[TBL] [Abstract][Full Text] [Related]
7. Delivery of messenger RNA using poly(ethylene imine)-poly(ethylene glycol)-copolymer blends for polyplex formation: biophysical characterization and in vitro transfection properties.
Debus H; Baumhof P; Probst J; Kissel T
J Control Release; 2010 Dec; 148(3):334-43. PubMed ID: 20854856
[TBL] [Abstract][Full Text] [Related]
8. Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung.
Günther M; Lipka J; Malek A; Gutsch D; Kreyling W; Aigner A
Eur J Pharm Biopharm; 2011 Apr; 77(3):438-49. PubMed ID: 21093588
[TBL] [Abstract][Full Text] [Related]
9. Maltose- and maltotriose-modified, hyperbranched poly(ethylene imine)s (OM-PEIs): Physicochemical and biological properties of DNA and siRNA complexes.
Höbel S; Loos A; Appelhans D; Schwarz S; Seidel J; Voit B; Aigner A
J Control Release; 2011 Jan; 149(2):146-58. PubMed ID: 20946922
[TBL] [Abstract][Full Text] [Related]
10. PEGylation affects cytotoxicity and cell-compatibility of poly(ethylene imine) for lung application: structure-function relationships.
Beyerle A; Merkel O; Stoeger T; Kissel T
Toxicol Appl Pharmacol; 2010 Jan; 242(2):146-54. PubMed ID: 19822165
[TBL] [Abstract][Full Text] [Related]
11. Nonviral pulmonary delivery of siRNA.
Merkel OM; Kissel T
Acc Chem Res; 2012 Jul; 45(7):961-70. PubMed ID: 21905687
[TBL] [Abstract][Full Text] [Related]
12. Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications.
Beyerle A; Irmler M; Beckers J; Kissel T; Stoeger T
Mol Pharm; 2010 Jun; 7(3):727-37. PubMed ID: 20429563
[TBL] [Abstract][Full Text] [Related]
13. Poly(ethylene imine) nanocarriers do not induce mutations nor oxidative DNA damage in vitro in MutaMouse FE1 cells.
Beyerle A; Long AS; White PA; Kissel T; Stoeger T
Mol Pharm; 2011 Jun; 8(3):976-81. PubMed ID: 21446747
[TBL] [Abstract][Full Text] [Related]
14. An inhalable β₂-adrenoceptor ligand-directed guanidinylated chitosan carrier for targeted delivery of siRNA to lung.
Luo Y; Zhai X; Ma C; Sun P; Fu Z; Liu W; Xu J
J Control Release; 2012 Aug; 162(1):28-36. PubMed ID: 22698944
[TBL] [Abstract][Full Text] [Related]
15. Biocompatibility and efficacy of oligomaltose-grafted poly(ethylene imine)s (OM-PEIs) for in vivo gene delivery.
Gutsch D; Appelhans D; Höbel S; Voit B; Aigner A
Mol Pharm; 2013 Dec; 10(12):4666-75. PubMed ID: 24175860
[TBL] [Abstract][Full Text] [Related]
16. PEG-b-PPS-b-PEI micelles and PEG-b-PPS/PEG-b-PPS-b-PEI mixed micelles as non-viral vectors for plasmid DNA: tumor immunotoxicity in B16F10 melanoma.
Velluto D; Thomas SN; Simeoni E; Swartz MA; Hubbell JA
Biomaterials; 2011 Dec; 32(36):9839-47. PubMed ID: 21924769
[TBL] [Abstract][Full Text] [Related]
17. Polymer-related off-target effects in non-viral siRNA delivery.
Merkel OM; Beyerle A; Beckmann BM; Zheng M; Hartmann RK; Stöger T; Kissel TH
Biomaterials; 2011 Mar; 32(9):2388-98. PubMed ID: 21183213
[TBL] [Abstract][Full Text] [Related]
18. Enhanced gene expression and reduced toxicity in mice using polyplexes of low-molecular-weight poly(ethylene imine) for pulmonary gene delivery.
Kleemann E; Jekel N; Dailey LA; Roesler S; Fink L; Weissmann N; Schermuly R; Gessler T; Schmehl T; Roberts CJ; Seeger W; Kissel T
J Drug Target; 2009 Sep; 17(8):638-51. PubMed ID: 19589123
[TBL] [Abstract][Full Text] [Related]
19. Amphiphilic, low molecular weight poly(ethylene imine) derivatives with enhanced stability for efficient pulmonary gene delivery.
Roesler S; Koch FP; Schmehl T; Weissmann N; Seeger W; Gessler T; Kissel T
J Gene Med; 2011 Feb; 13(2):123-33. PubMed ID: 21308899
[TBL] [Abstract][Full Text] [Related]
20. The use of CpG-free plasmids to mediate persistent gene expression following repeated aerosol delivery of pDNA/PEI complexes.
Davies LA; Hyde SC; Nunez-Alonso G; Bazzani RP; Harding-Smith R; Pringle IA; Lawton AE; Abdullah S; Roberts TC; McCormick D; Sumner-Jones SG; Gill DR
Biomaterials; 2012 Aug; 33(22):5618-27. PubMed ID: 22575838
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
