BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 21224348)

  • 1. Chromosome breakage is regulated by the interaction of the BLM helicase and topoisomerase IIalpha.
    Russell B; Bhattacharyya S; Keirsey J; Sandy A; Grierson P; Perchiniak E; Kavecansky J; Acharya S; Groden J
    Cancer Res; 2011 Jan; 71(2):561-71. PubMed ID: 21224348
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A tri-serine cluster within the topoisomerase IIα-interaction domain of the BLM helicase is required for regulating chromosome breakage in human cells.
    Behnfeldt JH; Acharya S; Tangeman L; Gocha AS; Keirsey J; Groden J
    Hum Mol Genet; 2018 Apr; 27(7):1241-1251. PubMed ID: 29385443
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bloom's syndrome and PICH helicases cooperate with topoisomerase IIα in centromere disjunction before anaphase.
    Rouzeau S; Cordelières FP; Buhagiar-Labarchède G; Hurbain I; Onclercq-Delic R; Gemble S; Magnaghi-Jaulin L; Jaulin C; Amor-Guéret M
    PLoS One; 2012; 7(4):e33905. PubMed ID: 22563370
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Telomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substrates.
    Bhattacharyya S; Keirsey J; Russell B; Kavecansky J; Lillard-Wetherell K; Tahmaseb K; Turchi JJ; Groden J
    J Biol Chem; 2009 May; 284(22):14966-77. PubMed ID: 19329795
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression.
    Ramamoorthy M; Tadokoro T; Rybanska I; Ghosh AK; Wersto R; May A; Kulikowicz T; Sykora P; Croteau DL; Bohr VA
    Nucleic Acids Res; 2012 Feb; 40(4):1621-35. PubMed ID: 22013166
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Geminin overexpression prevents the completion of topoisomerase IIα chromosome decatenation, leading to aneuploidy in human mammary epithelial cells.
    Gardner L; Malik R; Shimizu Y; Mullins N; ElShamy WM
    Breast Cancer Res; 2011 May; 13(3):R53. PubMed ID: 21595939
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution.
    Tsukada K; Jones SE; Bannister J; Durin MA; Vendrell I; Fawkes M; Fischer R; Kessler BM; Chapman JR; Blackford AN
    Mol Cell; 2024 Feb; 84(4):640-658.e10. PubMed ID: 38266639
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Localization of the Bloom syndrome helicase to punctate nuclear structures and the nuclear matrix and regulation during the cell cycle: comparison with the Werner's syndrome helicase.
    Gharibyan V; Youssoufian H
    Mol Carcinog; 1999 Dec; 26(4):261-73. PubMed ID: 10569803
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction between tumor suppressor adenomatous polyposis coli and topoisomerase IIalpha: implication for the G2/M transition.
    Wang Y; Azuma Y; Moore D; Osheroff N; Neufeld KL
    Mol Biol Cell; 2008 Oct; 19(10):4076-85. PubMed ID: 18632987
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BRCA1-mediated ubiquitination inhibits topoisomerase II alpha activity in response to oxidative stress.
    Shinagawa H; Miki Y; Yoshida K
    Antioxid Redox Signal; 2008 May; 10(5):939-49. PubMed ID: 18162055
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel chromatin tether domain controls topoisomerase IIα dynamics and mitotic chromosome formation.
    Lane AB; Giménez-Abián JF; Clarke DJ
    J Cell Biol; 2013 Nov; 203(3):471-86. PubMed ID: 24217621
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Collaborating functions of BLM and DNA topoisomerase I in regulating human rDNA transcription.
    Grierson PM; Acharya S; Groden J
    Mutat Res; 2013; 743-744():89-96. PubMed ID: 23261817
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation.
    Blackford AN; Nieminuszczy J; Schwab RA; Galanty Y; Jackson SP; Niedzwiedz W
    Mol Cell; 2015 Mar; 57(6):1133-1141. PubMed ID: 25794620
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metal ion interactions in the DNA cleavage/ligation active site of human topoisomerase IIalpha.
    Deweese JE; Guengerich FP; Burgin AB; Osheroff N
    Biochemistry; 2009 Sep; 48(38):8940-7. PubMed ID: 19697956
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fbxo28 promotes mitotic progression and regulates topoisomerase IIα-dependent DNA decatenation.
    Kratz AS; Richter KT; Schlosser YT; Schmitt M; Shumilov A; Delecluse HJ; Hoffmann I
    Cell Cycle; 2016 Dec; 15(24):3419-3431. PubMed ID: 27754753
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Topoisomerase IIalpha binding domains of adenomatous polyposis coli influence cell cycle progression and aneuploidy.
    Wang Y; Coffey RJ; Osheroff N; Neufeld KL
    PLoS One; 2010 Apr; 5(4):e9994. PubMed ID: 20368985
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Down-regulation of DNA topoisomerase IIalpha leads to prolonged cell cycle transit in G2 and early M phases and increased survival to microtubule-interacting agents.
    Skladanowski A; Côme MG; Sabisz M; Escargueil AE; Larsen AK
    Mol Pharmacol; 2005 Sep; 68(3):625-34. PubMed ID: 15942022
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RNA helicase A interacts with dsDNA and topoisomerase IIalpha.
    Zhou K; Choe KT; Zaidi Z; Wang Q; Mathews MB; Lee CG
    Nucleic Acids Res; 2003 May; 31(9):2253-60. PubMed ID: 12711669
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of the catalytic function of topoisomerase II alpha through association with RNA.
    Park SW; Parrott AM; Fritz DT; Park Y; Mathews MB; Lee CG
    Nucleic Acids Res; 2008 Nov; 36(19):6080-90. PubMed ID: 18820297
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cell-cycle regulation of the DNA topoisomerase IIalpha promoter is mediated by proximal CCAAT boxes: possible involvement of acetylation.
    Adachi N; Nomoto M; Kohno K; Koyama H
    Gene; 2000 Mar; 245(1):49-57. PubMed ID: 10713444
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.