161 related articles for article (PubMed ID: 21232847)
1. A rearranged EP300 gene in the human B-cell lymphoma cell line RC-K8 encodes a disabled transcriptional co-activator that contributes to cell growth and oncogenicity.
Garbati MR; Thompson RC; Haery L; Gilmore TD
Cancer Lett; 2011 Mar; 302(1):76-83. PubMed ID: 21232847
[TBL] [Abstract][Full Text] [Related]
2. Histone acetyltransferase-deficient p300 mutants in diffuse large B cell lymphoma have altered transcriptional regulatory activities and are required for optimal cell growth.
Haery L; Lugo-Picó JG; Henry RA; Andrews AJ; Gilmore TD
Mol Cancer; 2014 Feb; 13():29. PubMed ID: 24529102
[TBL] [Abstract][Full Text] [Related]
3. Histone acetyltransferase p300 is a coactivator for transcription factor REL and is C-terminally truncated in the human diffuse large B-cell lymphoma cell line RC-K8.
Garbati MR; Alço G; Gilmore TD
Cancer Lett; 2010 May; 291(2):237-45. PubMed ID: 19948376
[TBL] [Abstract][Full Text] [Related]
4. Evidence for an oncogenic modifier role for mutant histone acetyltransferases in diffuse large B-cell lymphoma.
Haery L; Mussakhan S; Waxman DJ; Gilmore TD
Leuk Lymphoma; 2016 Nov; 57(11):2661-71. PubMed ID: 27003102
[TBL] [Abstract][Full Text] [Related]
5. Genomic organization and expression of the rearranged REL proto-oncogene in the human B-cell lymphoma cell line RC-K8.
Kalaitzidis D; Gilmore TD
Genes Chromosomes Cancer; 2002 May; 34(1):129-35. PubMed ID: 11921291
[TBL] [Abstract][Full Text] [Related]
6. Inactivating mutations of acetyltransferase genes in B-cell lymphoma.
Pasqualucci L; Dominguez-Sola D; Chiarenza A; Fabbri G; Grunn A; Trifonov V; Kasper LH; Lerach S; Tang H; Ma J; Rossi D; Chadburn A; Murty VV; Mullighan CG; Gaidano G; Rabadan R; Brindle PK; Dalla-Favera R
Nature; 2011 Mar; 471(7337):189-95. PubMed ID: 21390126
[TBL] [Abstract][Full Text] [Related]
7. Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.
Nie M; Du L; Ren W; Joung J; Ye X; Shi X; Ciftci S; Liu D; Wu K; Zhang F; Pan-Hammarström Q
Cell Death Dis; 2021 Apr; 12(5):419. PubMed ID: 33911074
[TBL] [Abstract][Full Text] [Related]
8. Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL's in vitro transforming activity.
Starczynowski DT; Trautmann H; Pott C; Harder L; Arnold N; Africa JA; Leeman JR; Siebert R; Gilmore TD
Oncogene; 2007 Apr; 26(19):2685-94. PubMed ID: 17072339
[TBL] [Abstract][Full Text] [Related]
9. Cooperative activation of Npr1 gene transcription and expression by interaction of Ets-1 and p300.
Kumar P; Pandey KN
Hypertension; 2009 Jul; 54(1):172-8. PubMed ID: 19487584
[TBL] [Abstract][Full Text] [Related]
10. The human B-cell lymphoma cell line RC-K8 has multiple genetic alterations that dysregulate the Rel/NF-kappaB signal transduction pathway.
Kalaitzidis D; Davis RE; Rosenwald A; Staudt LM; Gilmore TD
Oncogene; 2002 Dec; 21(57):8759-68. PubMed ID: 12483529
[TBL] [Abstract][Full Text] [Related]
11. Alterations at the rel locus in human lymphoma.
Lu D; Thompson JD; Gorski GK; Rice NR; Mayer MG; Yunis JJ
Oncogene; 1991 Jul; 6(7):1235-41. PubMed ID: 1650444
[TBL] [Abstract][Full Text] [Related]
12. Recruitment of nuclear factor Y to the inverted CCAAT element (ICE) by c-Jun and E1A stimulates basal transcription of the bone sialoprotein gene in osteosarcoma cells.
Su M; Bansal AK; Mantovani R; Sodek J
J Biol Chem; 2005 Nov; 280(46):38365-75. PubMed ID: 16087680
[TBL] [Abstract][Full Text] [Related]
13. BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy.
Cerchietti LC; Hatzi K; Caldas-Lopes E; Yang SN; Figueroa ME; Morin RD; Hirst M; Mendez L; Shaknovich R; Cole PA; Bhalla K; Gascoyne RD; Marra M; Chiosis G; Melnick A
J Clin Invest; 2010 Dec; 120(12):4569-82. PubMed ID: 21041953
[TBL] [Abstract][Full Text] [Related]
14. CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.
Veazey KJ; Cheng D; Lin K; Villarreal OD; Gao G; Perez-Oquendo M; Van HT; Stratton SA; Green M; Xu H; Lu Y; Bedford MT; Santos MA
Leukemia; 2020 Dec; 34(12):3269-3285. PubMed ID: 32576962
[TBL] [Abstract][Full Text] [Related]
15. BMP2-activated Erk/MAP kinase stabilizes Runx2 by increasing p300 levels and histone acetyltransferase activity.
Jun JH; Yoon WJ; Seo SB; Woo KM; Kim GS; Ryoo HM; Baek JH
J Biol Chem; 2010 Nov; 285(47):36410-9. PubMed ID: 20851880
[TBL] [Abstract][Full Text] [Related]
16. Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies.
Scialdone A; Khazaei S; Hasni MS; Lennartsson A; Gullberg U; Drott K
Exp Hematol; 2019 Nov; 79():35-46.e1. PubMed ID: 31669559
[TBL] [Abstract][Full Text] [Related]
17. Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma.
Meyer SN; Scuoppo C; Vlasevska S; Bal E; Holmes AB; Holloman M; Garcia-Ibanez L; Nataraj S; Duval R; Vantrimpont T; Basso K; Brooks N; Dalla-Favera R; Pasqualucci L
Immunity; 2019 Sep; 51(3):535-547.e9. PubMed ID: 31519498
[TBL] [Abstract][Full Text] [Related]
18. Mutant envelope residues confer a transactivation function onto N-terminal sequences of the v-Rel oncoprotein.
Epinat JC; Kazandjian D; Harkness DD; Petros S; Dave J; White DW; Gilmore TD
Oncogene; 2000 Feb; 19(5):599-607. PubMed ID: 10698504
[TBL] [Abstract][Full Text] [Related]
19. Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile.
Chin M; Herscovitch M; Zhang N; Waxman DJ; Gilmore TD
Oncogene; 2009 May; 28(20):2100-11. PubMed ID: 19377508
[TBL] [Abstract][Full Text] [Related]
20. E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300.
Hyndman BD; Thompson P; Bayly R; Côté GP; LeBrun DP
Biochim Biophys Acta; 2012 May; 1819(5):446-53. PubMed ID: 22387215
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
