These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 21234655)

  • 1. The synthetic triterpenoid CDDO-Imidazolide suppresses experimental liver metastasis.
    Townson JL; Macdonald IC; Liby KT; Mackenzie L; Dales DW; Hedley BD; Foster PJ; Sporn MB; Chambers AF
    Clin Exp Metastasis; 2011 Mar; 28(3):309-17. PubMed ID: 21234655
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.
    Yates MS; Kwak MK; Egner PA; Groopman JD; Bodreddigari S; Sutter TR; Baumgartner KJ; Roebuck BD; Liby KT; Yore MM; Honda T; Gribble GW; Sporn MB; Kensler TW
    Cancer Res; 2006 Feb; 66(4):2488-94. PubMed ID: 16489057
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide.
    Shin S; Wakabayashi J; Yates MS; Wakabayashi N; Dolan PM; Aja S; Liby KT; Sporn MB; Yamamoto M; Kensler TW
    Eur J Pharmacol; 2009 Oct; 620(1-3):138-44. PubMed ID: 19698707
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.
    Place AE; Suh N; Williams CR; Risingsong R; Honda T; Honda Y; Gribble GW; Leesnitzer LM; Stimmel JB; Willson TM; Rosen E; Sporn MB
    Clin Cancer Res; 2003 Jul; 9(7):2798-806. PubMed ID: 12855660
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention.
    Cao M; Onyango EO; Williams CR; Royce DB; Gribble GW; Sporn MB; Liby KT
    Pharmacol Res; 2015 Oct; 100():135-47. PubMed ID: 26238177
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Complete protection against aflatoxin B(1)-induced liver cancer with a triterpenoid: DNA adduct dosimetry, molecular signature, and genotoxicity threshold.
    Johnson NM; Egner PA; Baxter VK; Sporn MB; Wible RS; Sutter TR; Groopman JD; Kensler TW; Roebuck BD
    Cancer Prev Res (Phila); 2014 Jul; 7(7):658-65. PubMed ID: 24662598
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The synthetic triterpenoid (CDDO-Im) inhibits STAT3, as well as IL-17, and improves DSS-induced colitis in mice.
    Fitzpatrick LR; Stonesifer E; Small JS; Liby KT
    Inflammopharmacology; 2014 Dec; 22(6):341-9. PubMed ID: 24715223
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The triterpenoid CDDO-imidazolide ameliorates mouse liver ischemia-reperfusion injury through activating the Nrf2/HO-1 pathway enhanced autophagy.
    Xu D; Chen L; Chen X; Wen Y; Yu C; Yao J; Wu H; Wang X; Xia Q; Kong X
    Cell Death Dis; 2017 Aug; 8(8):e2983. PubMed ID: 28796242
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells.
    Hyer ML; Croxton R; Krajewska M; Krajewski S; Kress CL; Lu M; Suh N; Sporn MB; Cryns VL; Zapata JM; Reed JC
    Cancer Res; 2005 Jun; 65(11):4799-808. PubMed ID: 15930300
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma.
    Kress CL; Konopleva M; Martínez-García V; Krajewska M; Lefebvre S; Hyer ML; McQueen T; Andreeff M; Reed JC; Zapata JM
    PLoS One; 2007 Jun; 2(6):e559. PubMed ID: 17593960
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CDDO-imidazolide induces DNA damage, G2/M arrest and apoptosis in BRCA1-mutated breast cancer cells.
    Kim EH; Deng CX; Sporn MB; Liby KT
    Cancer Prev Res (Phila); 2011 Mar; 4(3):425-34. PubMed ID: 21372041
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling.
    Liby K; Hock T; Yore MM; Suh N; Place AE; Risingsong R; Williams CR; Royce DB; Honda T; Honda Y; Gribble GW; Hill-Kapturczak N; Agarwal A; Sporn MB
    Cancer Res; 2005 Jun; 65(11):4789-98. PubMed ID: 15930299
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CDDO-imidazolide mediated inhibition of malignant cell growth in Waldenström macroglobulinemia.
    Elsawa SF; Novak AJ; Grote D; Konopleva M; Andreeff M; Witzig TE; Ansell SM
    Leuk Res; 2008 Dec; 32(12):1895-902. PubMed ID: 18468679
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CDDO-Im exerts antidepressant-like effects via the Nrf2/ARE pathway in a rat model of post-stroke depression.
    Hou X; Liu H; Ping Y; Zhang F; Zhi L; Jiang X; Zhang F; Song C; Zhang Z; Song J
    Brain Res Bull; 2021 Aug; 173():74-81. PubMed ID: 33991607
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells.
    Ji Y; Lee HJ; Goodman C; Uskokovic M; Liby K; Sporn M; Suh N
    Mol Cancer Ther; 2006 Jun; 5(6):1452-8. PubMed ID: 16818503
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling.
    Gao X; Deeb D; Jiang H; Liu Y; Dulchavsky SA; Gautam SC
    J Neurooncol; 2007 Sep; 84(2):147-57. PubMed ID: 17361329
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.
    Yates MS; Tauchi M; Katsuoka F; Flanders KC; Liby KT; Honda T; Gribble GW; Johnson DA; Johnson JA; Burton NC; Guilarte TR; Yamamoto M; Sporn MB; Kensler TW
    Mol Cancer Ther; 2007 Jan; 6(1):154-62. PubMed ID: 17237276
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer.
    Samudio I; Konopleva M; Hail N; Shi YX; McQueen T; Hsu T; Evans R; Honda T; Gribble GW; Sporn M; Gilbert HF; Safe S; Andreeff M
    J Biol Chem; 2005 Oct; 280(43):36273-82. PubMed ID: 16118208
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta.
    Yore MM; Liby KT; Honda T; Gribble GW; Sporn MB
    Mol Cancer Ther; 2006 Dec; 5(12):3232-9. PubMed ID: 17148759
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacological induction of heme oxygenase-1 by a triterpenoid protects neurons against ischemic injury.
    Zhang F; Wang S; Zhang M; Weng Z; Li P; Gan Y; Zhang L; Cao G; Gao Y; Leak RK; Sporn MB; Chen J
    Stroke; 2012 May; 43(5):1390-7. PubMed ID: 22461332
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.