309 related articles for article (PubMed ID: 21235378)
1. Neutrophil elastase inhibitors.
Groutas WC; Dou D; Alliston KR
Expert Opin Ther Pat; 2011 Mar; 21(3):339-54. PubMed ID: 21235378
[TBL] [Abstract][Full Text] [Related]
2. Targeting COPD: advances on low-molecular-weight inhibitors of human neutrophil elastase.
Lucas SD; Costa E; Guedes RC; Moreira R
Med Res Rev; 2013 Jun; 33 Suppl 1():E73-101. PubMed ID: 21681767
[TBL] [Abstract][Full Text] [Related]
3. Novel benzoxazinone derivative as potent human neutrophil elastase inhibitor: Potential implications in lung injury.
Sengupta S; Reddy JR; Rajesh N; Jaiswal A; Mabalirajan U; Palakodety RK; Mukherjee P; Bandyopadhyay A
Eur J Pharmacol; 2022 Sep; 931():175187. PubMed ID: 35952844
[TBL] [Abstract][Full Text] [Related]
4. Neutrophil elastase inhibitors: a patent review and potential applications for inflammatory lung diseases (2010 - 2014).
Tsai YF; Hwang TL
Expert Opin Ther Pat; 2015; 25(10):1145-58. PubMed ID: 26118988
[TBL] [Abstract][Full Text] [Related]
5. The Role of Neutrophil Elastase Inhibitors in Lung Diseases.
Polverino E; Rosales-Mayor E; Dale GE; Dembowsky K; Torres A
Chest; 2017 Aug; 152(2):249-262. PubMed ID: 28442313
[TBL] [Abstract][Full Text] [Related]
6. A patenting perspective on human neutrophil elastase (HNE) inhibitors (2014-2018) and their therapeutic applications.
Crocetti L; Quinn MT; Schepetkin IA; Giovannoni MP
Expert Opin Ther Pat; 2019 Jul; 29(7):555-578. PubMed ID: 31204543
[TBL] [Abstract][Full Text] [Related]
7. Neutrophil elastase inhibitors as treatment for COPD.
Ohbayashi H
Expert Opin Investig Drugs; 2002 Jul; 11(7):965-80. PubMed ID: 12084007
[TBL] [Abstract][Full Text] [Related]
8. The potential of neutrophil elastase inhibitors as anti-inflammatory therapies.
Henriksen PA
Curr Opin Hematol; 2014 Jan; 21(1):23-8. PubMed ID: 24241342
[TBL] [Abstract][Full Text] [Related]
9. [Proteases involved in airway inflammation of COPD].
Kasagi S; Seyama K; Fukuchi Y
Nihon Rinsho; 2003 Dec; 61(12):2113-8. PubMed ID: 14674319
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of neutrophil elastase prevents cigarette smoke exposure-induced formation of neutrophil extracellular traps and improves lung function in a mouse model of chronic obstructive pulmonary disease.
Wang K; Liao Y; Li X; Wang R; Zeng Z; Cheng M; Gao L; Xu D; Wen F; Wang T; Chen J
Int Immunopharmacol; 2023 Jan; 114():109537. PubMed ID: 36495695
[TBL] [Abstract][Full Text] [Related]
11. Crystalline form of a neutrophil elastase inhibitor, 6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-N-{[5-(methylsulfonyl)pyridin-2-yl]methyl}-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide p-toluene sulfonate - is it AZD-9668?: WO-2010094964.
Norman P
Expert Opin Ther Pat; 2011 Feb; 21(2):277-80. PubMed ID: 21222548
[TBL] [Abstract][Full Text] [Related]
12. Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors.
Dau T; Sarker RS; Yildirim AO; Eickelberg O; Jenne DE
Nat Commun; 2015 Apr; 6():6722. PubMed ID: 25857284
[TBL] [Abstract][Full Text] [Related]
13. Neutrophil Elastase Inhibitors and Chronic Kidney Disease.
Bronze-da-Rocha E; Santos-Silva A
Int J Biol Sci; 2018; 14(10):1343-1360. PubMed ID: 30123081
[TBL] [Abstract][Full Text] [Related]
14. Role of Proteases in Chronic Obstructive Pulmonary Disease.
Pandey KC; De S; Mishra PK
Front Pharmacol; 2017; 8():512. PubMed ID: 28848433
[TBL] [Abstract][Full Text] [Related]
15. Oxidized Alpha-1-Antitrypsin as a Potential Biomarker Associated with Onset and Severity of Chronic Obstructive Pulmonary Disease in Adult Population.
Topic A; Milovanovic V; Lazic Z; Ivosevic A; Radojkovic D
COPD; 2018 Oct; 15(5):472-478. PubMed ID: 30822244
[TBL] [Abstract][Full Text] [Related]
16. The preclinical pharmacology of roflumilast--a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease.
Hatzelmann A; Morcillo EJ; Lungarella G; Adnot S; Sanjar S; Beume R; Schudt C; Tenor H
Pulm Pharmacol Ther; 2010 Aug; 23(4):235-56. PubMed ID: 20381629
[TBL] [Abstract][Full Text] [Related]
17. TAILS proteomics reveals dynamic changes in airway proteolysis controlling protease activity and innate immunity during COPD exacerbations.
Mallia-Milanes B; Dufour A; Philp C; Solis N; Klein T; Fischer M; Bolton CE; Shapiro S; Overall CM; Johnson SR
Am J Physiol Lung Cell Mol Physiol; 2018 Dec; 315(6):L1003-L1014. PubMed ID: 30284925
[TBL] [Abstract][Full Text] [Related]
18. Human Antibody Domains and Fragments Targeting Neutrophil Elastase as Candidate Therapeutics for Cancer and Inflammation-Related Diseases.
Chu X; Sun Z; Baek DS; Li W; Mellors JW; Shapiro SD; Dimitrov DS
Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681796
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of neutrophil elastase attenuates airway hyperresponsiveness and inflammation in a mouse model of secondary allergen challenge: neutrophil elastase inhibition attenuates allergic airway responses.
Koga H; Miyahara N; Fuchimoto Y; Ikeda G; Waseda K; Ono K; Tanimoto Y; Kataoka M; Gelfand EW; Tanimoto M; Kanehiro A
Respir Res; 2013 Jan; 14(1):8. PubMed ID: 23347423
[TBL] [Abstract][Full Text] [Related]
20. Proteinase/proteinase inhibitor imbalance in sputum sol phases from patients with chronic obstructive pulmonary disease. Suggestions for a key role played by antileukoprotease.
Piccioni PD; Kramps JA; Rudolphus A; Bulgheroni A; Luisetti M
Chest; 1992 Nov; 102(5):1470-6. PubMed ID: 1385052
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]