BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 21235576)

  • 1. HDAC6 regulates aggresome-autophagy degradation pathway of α-synuclein in response to MPP+-induced stress.
    Su M; Shi JJ; Yang YP; Li J; Zhang YL; Chen J; Hu LF; Liu CF
    J Neurochem; 2011 Apr; 117(1):112-20. PubMed ID: 21235576
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MPP+ impairs autophagic clearance of alpha-synuclein by impairing the activity of dynein.
    Cai ZL; Shi JJ; Yang YP; Cao BY; Wang F; Huang JZ; Yang F; Zhang P; Liu CF
    Neuroreport; 2009 Apr; 20(6):569-73. PubMed ID: 19287320
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alpha-synuclein knockdown attenuates MPP+ induced mitochondrial dysfunction of SH-SY5Y cells.
    Wu F; Poon WS; Lu G; Wang A; Meng H; Feng L; Li Z; Liu S
    Brain Res; 2009 Oct; 1292():173-9. PubMed ID: 19646423
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interplay between HDAC6 and its interacting partners: essential roles in the aggresome-autophagy pathway and neurodegenerative diseases.
    Yan J
    DNA Cell Biol; 2014 Sep; 33(9):567-80. PubMed ID: 24932665
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heat shock proteins reduce alpha-synuclein aggregation induced by MPP+ in SK-N-SH cells.
    Fan GH; Zhou HY; Yang H; Chen SD
    FEBS Lett; 2006 May; 580(13):3091-8. PubMed ID: 16678164
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rifampicin protects PC12 cells against MPP+-induced apoptosis and inhibits the expression of an alpha-Synuclein multimer.
    Xu J; Wei C; Xu C; Bennett MC; Zhang G; Li F; Tao E
    Brain Res; 2007 Mar; 1139():220-5. PubMed ID: 17280646
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone deacetylase 6 regulates cytotoxic α-synuclein accumulation through induction of the heat shock response.
    Du Y; Wang F; Zou J; Le W; Dong Q; Wang Z; Shen F; Yu L; Li Y
    Neurobiol Aging; 2014 Oct; 35(10):2316-28. PubMed ID: 24866403
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of Protein Ubiquitination by Paraquat and 1-Methyl-4-Phenylpyridinium Impairs Ubiquitin-Dependent Protein Degradation Pathways.
    Navarro-Yepes J; Anandhan A; Bradley E; Bohovych I; Yarabe B; de Jong A; Ovaa H; Zhou Y; Khalimonchuk O; Quintanilla-Vega B; Franco R
    Mol Neurobiol; 2016 Oct; 53(8):5229-51. PubMed ID: 26409479
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dopamine induces autophagic cell death and alpha-synuclein increase in human neuroblastoma SH-SY5Y cells.
    Gómez-Santos C; Ferrer I; Santidrián AF; Barrachina M; Gil J; Ambrosio S
    J Neurosci Res; 2003 Aug; 73(3):341-50. PubMed ID: 12868068
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of autophagy in protection afforded by hypoxic preconditioning against MPP+-induced neurotoxicity in SH-SY5Y cells.
    Tzeng YW; Lee LY; Chao PL; Lee HC; Wu RT; Lin AM
    Free Radic Biol Med; 2010 Sep; 49(5):839-46. PubMed ID: 20541008
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential effects of overexpression of wild-type and mutant human alpha-synuclein on MPP+-induced neurotoxicity in PC12 cells.
    Qian JJ; Cheng YB; Yang YP; Mao CJ; Qin ZH; Li K; Liu CF
    Neurosci Lett; 2008 Apr; 435(2):142-6. PubMed ID: 18342443
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Wild-type alpha-synuclein interacts with pro-apoptotic proteins PKCdelta and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death.
    Kaul S; Anantharam V; Kanthasamy A; Kanthasamy AG
    Brain Res Mol Brain Res; 2005 Sep; 139(1):137-52. PubMed ID: 15978696
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Autophagy-dependent removal of α-synuclein: a novel mechanism of GM1 ganglioside neuroprotection against Parkinson's disease.
    Guo YL; Duan WJ; Lu DH; Ma XH; Li XX; Li Z; Bi W; Kurihara H; Liu HZ; Li YF; He RR
    Acta Pharmacol Sin; 2021 Apr; 42(4):518-528. PubMed ID: 32724177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. dl-3-n-Butylphthalide prevents oxidative damage and reduces mitochondrial dysfunction in an MPP(+)-induced cellular model of Parkinson's disease.
    Huang JZ; Chen YZ; Su M; Zheng HF; Yang YP; Chen J; Liu CF
    Neurosci Lett; 2010 May; 475(2):89-94. PubMed ID: 20347933
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a Drosophila model of Parkinson's disease.
    Lee FK; Wong AK; Lee YW; Wan OW; Chan HY; Chung KK
    J Neurochem; 2009 Jul; 110(1):208-19. PubMed ID: 19457126
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial impairment and oxidative stress compromise autophagosomal degradation of α-synuclein in oligodendroglial cells.
    Pukaß K; Goldbaum O; Richter-Landsberg C
    J Neurochem; 2015 Oct; 135(1):194-205. PubMed ID: 26212128
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease.
    Pan T; Kondo S; Le W; Jankovic J
    Brain; 2008 Aug; 131(Pt 8):1969-78. PubMed ID: 18187492
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-apoptotic effect of Mao-B inhibitor PF9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine] is mediated by p53 pathway inhibition in MPP+-treated SH-SY5Y human dopaminergic cells.
    Sanz E; Quintana A; Battaglia V; Toninello A; Hidalgo J; Ambrosio S; Valoti M; Marco JL; Tipton KF; Unzeta M
    J Neurochem; 2008 Jun; 105(6):2404-17. PubMed ID: 18331475
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity.
    Smith WW; Jiang H; Pei Z; Tanaka Y; Morita H; Sawa A; Dawson VL; Dawson TM; Ross CA
    Hum Mol Genet; 2005 Dec; 14(24):3801-11. PubMed ID: 16239241
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A cell-based model of alpha-synucleinopathy for screening compounds with therapeutic potential of Parkinson's disease.
    Zhao DL; Zou LB; Zhou LF; Zhu P; Zhu HB
    Acta Pharmacol Sin; 2007 May; 28(5):616-26. PubMed ID: 17439717
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.