BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 21236668)

  • 1. Enediol mimics as inhibitors of the D-arabinose 5-phosphate isomerase (KdsD) from Francisella tularensis.
    Yep A; Sorenson RJ; Wilson MR; Showalter HD; Larsen SD; Keller PR; Woodard RW
    Bioorg Med Chem Lett; 2011 May; 21(9):2679-82. PubMed ID: 21236668
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Arabinose 5-phosphate isomerase as a target for antibacterial design: studies with substrate analogues and inhibitors.
    Gabrielli L; Merlo S; Airoldi C; Sperandeo P; Gianera S; Polissi A; Nicotra F; Holler TP; Woodard RW; Cipolla L
    Bioorg Med Chem; 2014 Apr; 22(8):2576-83. PubMed ID: 24680056
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Isoprenoid biosynthesis as a target for antibacterial and antiparasitic drugs: phosphonohydroxamic acids as inhibitors of deoxyxylulose phosphate reducto-isomerase.
    Kuntz L; Tritsch D; Grosdemange-Billiard C; Hemmerlin A; Willem A; Bach TJ; Rohmer M
    Biochem J; 2005 Feb; 386(Pt 1):127-35. PubMed ID: 15473867
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modifications around the hydroxamic acid chelating group of fosmidomycin, an inhibitor of the metalloenzyme 1-deoxyxylulose 5-phosphate reductoisomerase (DXR).
    Zinglé C; Kuntz L; Tritsch D; Grosdemange-Billiard C; Rohmer M
    Bioorg Med Chem Lett; 2012 Nov; 22(21):6563-7. PubMed ID: 23025997
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure prediction and functional analysis of KdsD, an enzyme involved in lipopolysaccharide biosynthesis.
    Sommaruga S; Gioia LD; Tortora P; Polissi A
    Biochem Biophys Res Commun; 2009 Oct; 388(2):222-7. PubMed ID: 19664604
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting bacterial membranes: identification of Pseudomonas aeruginosa D-arabinose-5P isomerase and NMR characterisation of its substrate recognition and binding properties.
    Airoldi C; Sommaruga S; Merlo S; Sperandeo P; Cipolla L; Polissi A; Nicotra F
    Chembiochem; 2011 Mar; 12(5):719-27. PubMed ID: 21337483
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of the arabinose-5-phosphate isomerase of Bacteroides fragilis provides insight into regulation of single-domain arabinose phosphate isomerases.
    Cech D; Wang PF; Holler TP; Woodard RW
    J Bacteriol; 2014 Aug; 196(15):2861-8. PubMed ID: 24891442
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hydroxamic acids as potent inhibitors of Fe(II) and Mn(II) E. coli methionine aminopeptidase: biological activities and X-ray structures of oxazole hydroxamate-EcMetAP-Mn complexes.
    Huguet F; Melet A; Alves de Sousa R; Lieutaud A; Chevalier J; Maigre L; Deschamps P; Tomas A; Leulliot N; Pages JM; Artaud I
    ChemMedChem; 2012 Jun; 7(6):1020-30. PubMed ID: 22489069
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a d-Arabinose-5-Phosphate Isomerase in the Gram-Positive Clostridium tetani.
    Cech DL; Markin K; Woodard RW
    J Bacteriol; 2017 Sep; 199(17):. PubMed ID: 28630128
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-throughput catch-and-release synthesis of oxazoline hydroxamates. Structure-activity relationships in novel inhibitors of Escherichia coli LpxC: in vitro enzyme inhibition and antibacterial properties.
    Pirrung MC; Tumey LN; McClerren AL; Raetz CR
    J Am Chem Soc; 2003 Feb; 125(6):1575-86. PubMed ID: 12568618
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of Escherichia coli D-arabinose 5-phosphate isomerase encoded by kpsF: implications for group 2 capsule biosynthesis.
    Meredith TC; Woodard RW
    Biochem J; 2006 Apr; 395(2):427-32. PubMed ID: 16390329
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Competitive inhibitors of type B ribose 5-phosphate isomerases: design, synthesis and kinetic evaluation of new D-allose and D-allulose 6-phosphate derivatives.
    Mariano S; Roos AK; Mowbray SL; Salmon L
    Carbohydr Res; 2009 May; 344(7):869-80. PubMed ID: 19328460
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substitution of the phosphonic acid and hydroxamic acid functionalities of the DXR inhibitor FR900098: an attempt to improve the activity against Mycobacterium tuberculosis.
    Andaloussi M; Lindh M; Björkelid C; Suresh S; Wieckowska A; Iyer H; Karlén A; Larhed M
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5403-7. PubMed ID: 21824775
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Towards new antimalarial drugs: synthesis of non-hydrolyzable phosphate mimics as feed for a predictive QSAR study on 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.
    Giessmann D; Heidler P; Haemers T; Van Calenbergh S; Reichenberg A; Jomaa H; Weidemeyer C; Sanderbrand S; Wiesner J; Link A
    Chem Biodivers; 2008 Apr; 5(4):643-56. PubMed ID: 18421757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A fragment-based approach to understanding inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
    Mercklé L; de Andrés-Gómez A; Dick B; Cox RJ; Godfrey CR
    Chembiochem; 2005 Oct; 6(10):1866-74. PubMed ID: 16116659
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Peptide deformylase inhibitors with non-peptide scaffold: synthesis and structure-activity relationships.
    Lee SK; Choi KH; Lee SJ; Lee JS; Park JY; Kim BM; Lee BJ
    Bioorg Med Chem Lett; 2011 Jan; 21(1):133-6. PubMed ID: 21146987
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI).
    Mehboob S; Song J; Hevener KE; Su PC; Boci T; Brubaker L; Truong L; Mistry T; Deng J; Cook JL; Santarsiero BD; Ghosh AK; Johnson ME
    Bioorg Med Chem Lett; 2015 Mar; 25(6):1292-6. PubMed ID: 25677657
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Catechol-rhodanine derivatives: Specific and promiscuous inhibitors of Escherichia coli deoxyxylulose phosphate reductoisomerase (DXR).
    Zinglé C; Tritsch D; Grosdemange-Billiard C; Rohmer M
    Bioorg Med Chem; 2014 Jul; 22(14):3713-9. PubMed ID: 24890653
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antimicrobial N-(2-chlorobenzyl)-substituted hydroxamate is an inhibitor of 1-deoxy-D-xylulose 5-phosphate synthase.
    Hayashi D; Kato N; Kuzuyama T; Sato Y; Ohkanda J
    Chem Commun (Camb); 2013 Jun; 49(49):5535-7. PubMed ID: 23476925
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of GutQ from Escherichia coli as a D-arabinose 5-phosphate isomerase.
    Meredith TC; Woodard RW
    J Bacteriol; 2005 Oct; 187(20):6936-42. PubMed ID: 16199563
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.