These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
169 related articles for article (PubMed ID: 21239472)
1. 6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1. Yuan B; Zhang J; Wang H; Xiong L; Cai Q; Wang T; Jacobsen S; Pradhan S; Wang Y Cancer Res; 2011 Mar; 71(5):1904-11. PubMed ID: 21239472 [TBL] [Abstract][Full Text] [Related]
2. Cyclophosphamide perturbs cytosine methylation in Jurkat-T cells through LSD1-mediated stabilization of DNMT1 protein. Zhang J; Yuan B; Zhang F; Xiong L; Wu J; Pradhan S; Wang Y Chem Res Toxicol; 2011 Nov; 24(11):2040-3. PubMed ID: 22007908 [TBL] [Abstract][Full Text] [Related]
3. 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal. Ghoshal K; Datta J; Majumder S; Bai S; Kutay H; Motiwala T; Jacob ST Mol Cell Biol; 2005 Jun; 25(11):4727-41. PubMed ID: 15899874 [TBL] [Abstract][Full Text] [Related]
4. 6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo. Wang H; Wang Y Biochemistry; 2009 Mar; 48(10):2290-9. PubMed ID: 19236003 [TBL] [Abstract][Full Text] [Related]
5. A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation. Datta J; Ghoshal K; Denny WA; Gamage SA; Brooke DG; Phiasivongsa P; Redkar S; Jacob ST Cancer Res; 2009 May; 69(10):4277-85. PubMed ID: 19417133 [TBL] [Abstract][Full Text] [Related]
6. Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappaB-dependent DNA methyltransferase activity in acute myeloid leukemia. Liu S; Liu Z; Xie Z; Pang J; Yu J; Lehmann E; Huynh L; Vukosavljevic T; Takeki M; Klisovic RB; Baiocchi RA; Blum W; Porcu P; Garzon R; Byrd JC; Perrotti D; Caligiuri MA; Chan KK; Wu LC; Marcucci G Blood; 2008 Feb; 111(4):2364-73. PubMed ID: 18083845 [TBL] [Abstract][Full Text] [Related]
7. Involvement of the concentrative nucleoside transporter 3 and equilibrative nucleoside transporter 2 in the resistance of T-lymphoblastic cell lines to thiopurines. Fotoohi AK; Lindqvist M; Peterson C; Albertioni F Biochem Biophys Res Commun; 2006 Apr; 343(1):208-15. PubMed ID: 16530731 [TBL] [Abstract][Full Text] [Related]
8. Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation. Zhou Q; Atadja P; Davidson NE Cancer Biol Ther; 2007 Jan; 6(1):64-9. PubMed ID: 17172825 [TBL] [Abstract][Full Text] [Related]
9. DNA methyltransferase 1 knock down induces gene expression by a mechanism independent of DNA methylation and histone deacetylation. Milutinovic S; Brown SE; Zhuang Q; Szyf M J Biol Chem; 2004 Jul; 279(27):27915-27. PubMed ID: 15087453 [TBL] [Abstract][Full Text] [Related]
10. Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells. Zhou Q; Agoston AT; Atadja P; Nelson WG; Davidson NE Mol Cancer Res; 2008 May; 6(5):873-83. PubMed ID: 18505931 [TBL] [Abstract][Full Text] [Related]
11. LC-MS/MS coupled with stable isotope dilution method for the quantification of 6-thioguanine and S(6)-methylthioguanine in genomic DNA of human cancer cells treated with 6-thioguanine. Wang H; Wang Y Anal Chem; 2010 Jul; 82(13):5797-803. PubMed ID: 20550170 [TBL] [Abstract][Full Text] [Related]
12. 6-thioguanine induces mitochondrial dysfunction and oxidative DNA damage in acute lymphoblastic leukemia cells. Zhang F; Fu L; Wang Y Mol Cell Proteomics; 2013 Dec; 12(12):3803-11. PubMed ID: 24043426 [TBL] [Abstract][Full Text] [Related]
13. Targeting of 5-aza-2'-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme. Patel K; Dickson J; Din S; Macleod K; Jodrell D; Ramsahoye B Nucleic Acids Res; 2010 Jul; 38(13):4313-24. PubMed ID: 20348135 [TBL] [Abstract][Full Text] [Related]
15. Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter. Wu LP; Wang X; Li L; Zhao Y; Lu S; Yu Y; Zhou W; Liu X; Yang J; Zheng Z; Zhang H; Feng J; Yang Y; Wang H; Zhu WG Mol Cell Biol; 2008 May; 28(10):3219-35. PubMed ID: 18332107 [TBL] [Abstract][Full Text] [Related]
16. The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Wang J; Hevi S; Kurash JK; Lei H; Gay F; Bajko J; Su H; Sun W; Chang H; Xu G; Gaudet F; Li E; Chen T Nat Genet; 2009 Jan; 41(1):125-9. PubMed ID: 19098913 [TBL] [Abstract][Full Text] [Related]
17. The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment. Coulthard SA; Matheson EC; Hall AG; Hogarth LA Nucleosides Nucleotides Nucleic Acids; 2004 Oct; 23(8-9):1385-91. PubMed ID: 15571264 [TBL] [Abstract][Full Text] [Related]
18. The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent. Brenner C; Luciani J; Bizet M; Ndlovu M; Josseaux E; Dedeurwaerder S; Calonne E; Putmans P; Cartron PF; Defrance M; Fuks F; Deplus R Oncotarget; 2016 Sep; 7(37):58939-58952. PubMed ID: 27449289 [TBL] [Abstract][Full Text] [Related]
19. Peperomin E reactivates silenced tumor suppressor genes in lung cancer cells by inhibition of DNA methyltransferase. Wang XZ; Cheng Y; Wang KL; Liu R; Yang XL; Wen HM; Chai C; Liang JY; Wu H Cancer Sci; 2016 Oct; 107(10):1506-1519. PubMed ID: 27501331 [TBL] [Abstract][Full Text] [Related]
20. DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta. Novakovic B; Wong NC; Sibson M; Ng HK; Morley R; Manuelpillai U; Down T; Rakyan VK; Beck S; Hiendleder S; Roberts CT; Craig JM; Saffery R J Biol Chem; 2010 Mar; 285(13):9583-9593. PubMed ID: 20071334 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]