254 related articles for article (PubMed ID: 21239497)
1. Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism.
An S; Yeo KJ; Jeon YH; Song JJ
J Biol Chem; 2011 Mar; 286(10):8369-8374. PubMed ID: 21239497
[TBL] [Abstract][Full Text] [Related]
2. Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase.
Rogawski DS; Ndoj J; Cho HJ; Maillard I; Grembecka J; Cierpicki T
Biochemistry; 2015 Sep; 54(35):5401-13. PubMed ID: 26292256
[TBL] [Abstract][Full Text] [Related]
3. Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.
Hou P; Huang C; Liu CP; Yang N; Yu T; Yin Y; Zhu B; Xu RM
Structure; 2019 May; 27(5):837-845.e3. PubMed ID: 30827843
[TBL] [Abstract][Full Text] [Related]
4. Structural Basis of MRG15-Mediated Activation of the ASH1L Histone Methyltransferase by Releasing an Autoinhibitory Loop.
Lee Y; Yoon E; Cho S; Schmähling S; Müller J; Song JJ
Structure; 2019 May; 27(5):846-852.e3. PubMed ID: 30827841
[TBL] [Abstract][Full Text] [Related]
5. Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes.
Gregory GD; Vakoc CR; Rozovskaia T; Zheng X; Patel S; Nakamura T; Canaani E; Blobel GA
Mol Cell Biol; 2007 Dec; 27(24):8466-79. PubMed ID: 17923682
[TBL] [Abstract][Full Text] [Related]
6. MRG15 activates histone methyltransferase activity of ASH1L by recruiting it to the nucleosomes.
Al-Harthi S; Li H; Winkler A; Szczepski K; Deng J; Grembecka J; Cierpicki T; Jaremko Ł
Structure; 2023 Oct; 31(10):1200-1207.e5. PubMed ID: 37527654
[TBL] [Abstract][Full Text] [Related]
7. Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.
Patel A; Vought VE; Swatkoski S; Viggiano S; Howard B; Dharmarajan V; Monteith KE; Kupakuwana G; Namitz KE; Shinsky SA; Cotter RJ; Cosgrove MS
J Biol Chem; 2014 Jan; 289(2):868-84. PubMed ID: 24235145
[TBL] [Abstract][Full Text] [Related]
8. Trithorax-group protein ASH1 methylates histone H3 lysine 36.
Tanaka Y; Katagiri Z; Kawahashi K; Kioussis D; Kitajima S
Gene; 2007 Aug; 397(1-2):161-8. PubMed ID: 17544230
[TBL] [Abstract][Full Text] [Related]
9. Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2.
Eram MS; Kuznetsova E; Li F; Lima-Fernandes E; Kennedy S; Chau I; Arrowsmith CH; Schapira M; Vedadi M
Biochim Biophys Acta; 2015 Sep; 1850(9):1842-8. PubMed ID: 26002201
[TBL] [Abstract][Full Text] [Related]
10. Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins.
Xu S; Zhong C; Zhang T; Ding J
J Mol Cell Biol; 2011 Oct; 3(5):293-300. PubMed ID: 21724641
[TBL] [Abstract][Full Text] [Related]
11. The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation.
Qiao Q; Li Y; Chen Z; Wang M; Reinberg D; Xu RM
J Biol Chem; 2011 Mar; 286(10):8361-8368. PubMed ID: 21196496
[TBL] [Abstract][Full Text] [Related]
12. Crystal Structure of MLL2 Complex Guides the Identification of a Methylation Site on P53 Catalyzed by KMT2 Family Methyltransferases.
Li Y; Zhao L; Tian X; Peng C; Gong F; Chen Y
Structure; 2020 Oct; 28(10):1141-1148.e4. PubMed ID: 32697937
[TBL] [Abstract][Full Text] [Related]
13. Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencing.
Miyazaki H; Higashimoto K; Yada Y; Endo TA; Sharif J; Komori T; Matsuda M; Koseki Y; Nakayama M; Soejima H; Handa H; Koseki H; Hirose S; Nishioka K
PLoS Genet; 2013 Nov; 9(11):e1003897. PubMed ID: 24244179
[TBL] [Abstract][Full Text] [Related]
14. Unleashing the Power of ASH1L Methyltransferase.
De I; Müller CW
Structure; 2019 May; 27(5):727-728. PubMed ID: 31067442
[TBL] [Abstract][Full Text] [Related]
15. Crystal structure of cardiac-specific histone methyltransferase SmyD1 reveals unusual active site architecture.
Sirinupong N; Brunzelle J; Ye J; Pirzada A; Nico L; Yang Z
J Biol Chem; 2010 Dec; 285(52):40635-44. PubMed ID: 20943667
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure and functional analysis of the histone methyltransferase SET7/9.
Wilson JR; Jing C; Walker PA; Martin SR; Howell SA; Blackburn GM; Gamblin SJ; Xiao B
Cell; 2002 Oct; 111(1):105-15. PubMed ID: 12372304
[TBL] [Abstract][Full Text] [Related]
17. ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.
Zhu L; Li Q; Wong SH; Huang M; Klein BJ; Shen J; Ikenouye L; Onishi M; Schneidawind D; Buechele C; Hansen L; Duque-Afonso J; Zhu F; Martin GM; Gozani O; Majeti R; Kutateladze TG; Cleary ML
Cancer Discov; 2016 Jul; 6(7):770-83. PubMed ID: 27154821
[TBL] [Abstract][Full Text] [Related]
18. Ash1 counteracts Polycomb repression independent of histone H3 lysine 36 methylation.
Dorafshan E; Kahn TG; Glotov A; Savitsky M; Walther M; Reuter G; Schwartz YB
EMBO Rep; 2019 Apr; 20(4):. PubMed ID: 30833342
[TBL] [Abstract][Full Text] [Related]
19. Histone H2A ubiquitination inhibits the enzymatic activity of H3 lysine 36 methyltransferases.
Yuan G; Ma B; Yuan W; Zhang Z; Chen P; Ding X; Feng L; Shen X; Chen S; Li G; Zhu B
J Biol Chem; 2013 Oct; 288(43):30832-42. PubMed ID: 24019522
[TBL] [Abstract][Full Text] [Related]
20. Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27).
McCabe MT; Graves AP; Ganji G; Diaz E; Halsey WS; Jiang Y; Smitheman KN; Ott HM; Pappalardi MB; Allen KE; Chen SB; Della Pietra A; Dul E; Hughes AM; Gilbert SA; Thrall SH; Tummino PJ; Kruger RG; Brandt M; Schwartz B; Creasy CL
Proc Natl Acad Sci U S A; 2012 Feb; 109(8):2989-94. PubMed ID: 22323599
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
