These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
409 related articles for article (PubMed ID: 21241072)
1. Quantitative prediction of human pharmacokinetics for monoclonal antibodies: retrospective analysis of monkey as a single species for first-in-human prediction. Dong JQ; Salinger DH; Endres CJ; Gibbs JP; Hsu CP; Stouch BJ; Hurh E; Gibbs MA Clin Pharmacokinet; 2011 Feb; 50(2):131-42. PubMed ID: 21241072 [TBL] [Abstract][Full Text] [Related]
2. Comparison of Various Approaches to Translate Non-Linear Pharmacokinetics of Monoclonal Antibodies from Cynomolgus Monkey to Human. Singh R; Moreno M; Stanimirovic D Eur J Drug Metab Pharmacokinet; 2021 Jul; 46(4):555-567. PubMed ID: 34120326 [TBL] [Abstract][Full Text] [Related]
3. Linear pharmacokinetic parameters for monoclonal antibodies are similar within a species and across different pharmacological targets: A comparison between human, cynomolgus monkey and hFcRn Tg32 transgenic mouse using a population-modeling approach. Betts A; Keunecke A; van Steeg TJ; van der Graaf PH; Avery LB; Jones H; Berkhout J MAbs; 2018 Jul; 10(5):751-764. PubMed ID: 29634430 [TBL] [Abstract][Full Text] [Related]
4. Towards a better prediction of peak concentration, volume of distribution and half-life after oral drug administration in man, using allometry. Sinha VK; Vaarties K; De Buck SS; Fenu LA; Nijsen M; Gilissen RA; Sanderson W; Van Uytsel K; Hoeben E; Van Peer A; Mackie CE; Smit JW Clin Pharmacokinet; 2011 May; 50(5):307-18. PubMed ID: 21456631 [TBL] [Abstract][Full Text] [Related]
5. Translational Approach for Predicting Human Pharmacokinetics of Engineered Therapeutic Monoclonal Antibodies with Increased FcRn-Binding Mutations. Haraya K; Tachibana T BioDrugs; 2023 Jan; 37(1):99-108. PubMed ID: 36449140 [TBL] [Abstract][Full Text] [Related]
6. Non-Clinical Pharmacokinetics, Prediction of Human Pharmacokinetics and First-in-Human Dose Selection for CNTO 5825, an Anti-Interleukin-13 Monoclonal Antibody. Nnane IP; Xu Z; Zhou H; Davis HM Basic Clin Pharmacol Toxicol; 2015 Oct; 117(4):219-25. PubMed ID: 25683750 [TBL] [Abstract][Full Text] [Related]
7. Projecting human pharmacokinetics of therapeutic antibodies from nonclinical data: what have we learned? Deng R; Iyer S; Theil FP; Mortensen DL; Fielder PJ; Prabhu S MAbs; 2011; 3(1):61-6. PubMed ID: 20962582 [TBL] [Abstract][Full Text] [Related]
8. Prediction of Human Pharmacokinetics of Antibody-Drug Conjugates From Nonclinical Data. Li C; Zhang C; Deng R; Leipold D; Li D; Latifi B; Gao Y; Zhang C; Li Z; Miles D; Chen SC; Samineni D; Wang B; Agarwal P; Lu D; Prabhu S; Girish S; Kamath AV Clin Transl Sci; 2019 Sep; 12(5):534-544. PubMed ID: 31115997 [TBL] [Abstract][Full Text] [Related]
9. Population pharmacokinetics of therapeutic monoclonal antibodies. Dirks NL; Meibohm B Clin Pharmacokinet; 2010 Oct; 49(10):633-59. PubMed ID: 20818831 [TBL] [Abstract][Full Text] [Related]
10. Simple Approach to Accurately Predict Pharmacokinetics of Therapeutic Monoclonal Antibodies after Subcutaneous Injection in Humans. Haraya K; Tachibana T Clin Pharmacokinet; 2021 Jan; 60(1):111-120. PubMed ID: 32779124 [TBL] [Abstract][Full Text] [Related]
11. A guide to rational dosing of monoclonal antibodies. Bai S; Jorga K; Xin Y; Jin D; Zheng Y; Damico-Beyer LA; Gupta M; Tang M; Allison DE; Lu D; Zhang Y; Joshi A; Dresser MJ Clin Pharmacokinet; 2012 Feb; 51(2):119-35. PubMed ID: 22257150 [TBL] [Abstract][Full Text] [Related]
12. Improving priors for human monoclonal antibody linear pharmacokinetic parameters by using half-lives from non-human primates. Shivva V; Fink M; Lowe PJ J Pharmacokinet Pharmacodyn; 2021 Apr; 48(2):295-303. PubMed ID: 33389522 [TBL] [Abstract][Full Text] [Related]
13. Prediction of human pharmacokinetics of therapeutic monoclonal antibodies from simple allometry of monkey data. Oitate M; Masubuchi N; Ito T; Yabe Y; Karibe T; Aoki T; Murayama N; Kurihara A; Okudaira N; Izumi T Drug Metab Pharmacokinet; 2011; 26(4):423-30. PubMed ID: 21606605 [TBL] [Abstract][Full Text] [Related]
14. Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose. de Vries Schultink AHM; Doornbos RP; Bakker ABH; Bol K; Throsby M; Geuijen C; Maussang D; Schellens JHM; Beijnen JH; Huitema ADR Invest New Drugs; 2018 Dec; 36(6):1006-1015. PubMed ID: 29728897 [TBL] [Abstract][Full Text] [Related]
15. Preclinical pharmacokinetics, interspecies scaling, and pharmacokinetics of a Phase I clinical trial of TTAC-0001, a fully human monoclonal antibody against vascular endothelial growth factor 2. Lee WS; Shim SR; Lee SY; Yoo JS; Cho SK Drug Des Devel Ther; 2018; 12():495-504. PubMed ID: 29563774 [TBL] [Abstract][Full Text] [Related]
16. A Quantitative Prediction Method for the Human Pharmacokinetics of Fc-Fusion Proteins. Yokoyama M; Suzuki E; Oitate M; Watanabe N Eur J Drug Metab Pharmacokinet; 2023 Sep; 48(5):541-552. PubMed ID: 37530974 [TBL] [Abstract][Full Text] [Related]
17. Prediction of human plasma concentration-time profiles of monoclonal antibodies from monkey data by a species-invariant time method. Oitate M; Nakayama S; Ito T; Kurihara A; Okudaira N; Izumi T Drug Metab Pharmacokinet; 2012; 27(3):354-9. PubMed ID: 22146109 [TBL] [Abstract][Full Text] [Related]
18. A Single Animal Species-Based Prediction of Human Clearance and First-in-Human Dose of Monoclonal Antibodies: Beyond Monkey. Mahmood I Antibodies (Basel); 2021 Sep; 10(3):. PubMed ID: 34562983 [TBL] [Abstract][Full Text] [Related]
19. Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies. Avery LB; Wang M; Kavosi MS; Joyce A; Kurz JC; Fan YY; Dowty ME; Zhang M; Zhang Y; Cheng A; Hua F; Jones HM; Neubert H; Polzer RJ; O'Hara DM MAbs; 2016; 8(6):1064-78. PubMed ID: 27232760 [TBL] [Abstract][Full Text] [Related]
20. A model-based meta-analysis of monoclonal antibody pharmacokinetics to guide optimal first-in-human study design. Davda JP; Dodds MG; Gibbs MA; Wisdom W; Gibbs J MAbs; 2014; 6(4):1094-102. PubMed ID: 24837591 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]