BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 21241253)

  • 1. How the biotin-streptavidin interaction was made even stronger: investigation via crystallography and a chimaeric tetramer.
    Chivers CE; Koner AL; Lowe ED; Howarth M
    Biochem J; 2011 Apr; 435(1):55-63. PubMed ID: 21241253
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Crystal Structure of Monovalent Streptavidin.
    Zhang M; Biswas S; Deng W; Yu H
    Sci Rep; 2016 Dec; 6():35915. PubMed ID: 28000673
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Love-Hate ligands for high resolution analysis of strain in ultra-stable protein/small molecule interaction.
    Fairhead M; Shen D; Chan LK; Lowe ED; Donohoe TJ; Howarth M
    Bioorg Med Chem; 2014 Oct; 22(19):5476-86. PubMed ID: 25128469
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
    Katz BA
    J Mol Biol; 1997 Dec; 274(5):776-800. PubMed ID: 9405158
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ser45 plays an important role in managing both the equilibrium and transition state energetics of the streptavidin-biotin system.
    Hyre DE; Le Trong I; Freitag S; Stenkamp RE; Stayton PS
    Protein Sci; 2000 May; 9(5):878-85. PubMed ID: 10850797
    [TBL] [Abstract][Full Text] [Related]  

  • 6. X-ray crystallographic studies of streptavidin mutants binding to biotin.
    Freitag S; Le Trong I; Klumb LA; Chu V; Chilkoti A; Stayton PS; Stenkamp RE
    Biomol Eng; 1999 Dec; 16(1-4):13-9. PubMed ID: 10796980
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural consequences of cutting a binding loop: two circularly permuted variants of streptavidin.
    Le Trong I; Chu V; Xing Y; Lybrand TP; Stayton PS; Stenkamp RE
    Acta Crystallogr D Biol Crystallogr; 2013 Jun; 69(Pt 6):968-77. PubMed ID: 23695241
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Second-contact shell mutation diminishes streptavidin-biotin binding affinity through transmitted effects on equilibrium dynamics.
    Baugh L; Le Trong I; Cerutti DS; Mehta N; Gülich S; Stayton PS; Stenkamp RE; Lybrand TP
    Biochemistry; 2012 Jan; 51(2):597-607. PubMed ID: 22145986
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of streptavidin mutant with low immunogenicity.
    Kawato T; Mizohata E; Meshizuka T; Doi H; Kawamura T; Matsumura H; Yumura K; Tsumoto K; Kodama T; Inoue T; Sugiyama A
    J Biosci Bioeng; 2015 Jun; 119(6):642-7. PubMed ID: 25434833
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thermodynamic and structural consequences of flexible loop deletion by circular permutation in the streptavidin-biotin system.
    Chu V; Freitag S; Le Trong I; Stenkamp RE; Stayton PS
    Protein Sci; 1998 Apr; 7(4):848-59. PubMed ID: 9568892
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural studies of the streptavidin binding loop.
    Freitag S; Le Trong I; Klumb L; Stayton PS; Stenkamp RE
    Protein Sci; 1997 Jun; 6(6):1157-66. PubMed ID: 9194176
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of CH/π interactions in the high affinity binding of streptavidin and biotin.
    Ozawa M; Ozawa T; Nishio M; Ueda K
    J Mol Graph Model; 2017 Aug; 75():117-124. PubMed ID: 28551501
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cooperative hydrogen bond interactions in the streptavidin-biotin system.
    Hyre DE; Le Trong I; Merritt EA; Eccleston JF; Green NM; Stenkamp RE; Stayton PS
    Protein Sci; 2006 Mar; 15(3):459-67. PubMed ID: 16452627
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-based engineering of streptavidin monomer with a reduced biotin dissociation rate.
    Demonte D; Drake EJ; Lim KH; Gulick AM; Park S
    Proteins; 2013 Sep; 81(9):1621-33. PubMed ID: 23670729
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding.
    Magalhães ML; Czekster CM; Guan R; Malashkevich VN; Almo SC; Levy M
    Protein Sci; 2011 Jul; 20(7):1145-54. PubMed ID: 21520321
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biotin's Lessons in Drug Design.
    McConnell DB
    J Med Chem; 2021 Nov; 64(22):16319-16327. PubMed ID: 34784474
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Plug-and-play pairing via defined divalent streptavidins.
    Fairhead M; Krndija D; Lowe ED; Howarth M
    J Mol Biol; 2014 Jan; 426(1):199-214. PubMed ID: 24056174
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystallographic analysis of a full-length streptavidin with its C-terminal polypeptide bound in the biotin binding site.
    Le Trong I; Humbert N; Ward TR; Stenkamp RE
    J Mol Biol; 2006 Feb; 356(3):738-45. PubMed ID: 16384581
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Streptavidin-biotin binding energetics.
    Stayton PS; Freitag S; Klumb LA; Chilkoti A; Chu V; Penzotti JE; To R; Hyre D; Le Trong I; Lybrand TP; Stenkamp RE
    Biomol Eng; 1999 Dec; 16(1-4):39-44. PubMed ID: 10796983
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Early mechanistic events in biotin dissociation from streptavidin.
    Hyre DE; Amon LM; Penzotti JE; Le Trong I; Stenkamp RE; Lybrand TP; Stayton PS
    Nat Struct Biol; 2002 Aug; 9(8):582-5. PubMed ID: 12134141
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.