BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

574 related articles for article (PubMed ID: 21241801)

  • 1. Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons.
    Calkins MJ; Reddy PH
    Biochim Biophys Acta; 2011 Apr; 1812(4):507-13. PubMed ID: 21241801
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease.
    Calkins MJ; Manczak M; Mao P; Shirendeb U; Reddy PH
    Hum Mol Genet; 2011 Dec; 20(23):4515-29. PubMed ID: 21873260
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synaptic Mitochondria: An Early Target of Amyloid-β and Tau in Alzheimer's Disease.
    Torres AK; Jara C; Park-Kang HS; Polanco CM; Tapia D; Alarcón F; de la Peña A; Llanquinao J; Vargas-Mardones G; Indo JA; Inestrosa NC; Tapia-Rojas C
    J Alzheimers Dis; 2021; 84(4):1391-1414. PubMed ID: 34719499
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons.
    Guo L; Du H; Yan S; Wu X; McKhann GM; Chen JX; Yan SS
    PLoS One; 2013; 8(1):e54914. PubMed ID: 23382999
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
    Manczak M; Kandimalla R; Fry D; Sesaki H; Reddy PH
    Hum Mol Genet; 2016 Dec; 25(23):5148-5166. PubMed ID: 27677309
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
    J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline.
    Reddy PH; Manczak M; Mao P; Calkins MJ; Reddy AP; Shirendeb U
    J Alzheimers Dis; 2010; 20 Suppl 2(Suppl 2):S499-512. PubMed ID: 20413847
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression.
    Manczak M; Anekonda TS; Henson E; Park BS; Quinn J; Reddy PH
    Hum Mol Genet; 2006 May; 15(9):1437-49. PubMed ID: 16551656
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics.
    Reddy PH; Tripathi R; Troung Q; Tirumala K; Reddy TP; Anekonda V; Shirendeb UP; Calkins MJ; Reddy AP; Mao P; Manczak M
    Biochim Biophys Acta; 2012 May; 1822(5):639-49. PubMed ID: 22037588
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gain of PITRM1 peptidase in cortical neurons affords protection of mitochondrial and synaptic function in an advanced age mouse model of Alzheimer's disease.
    Du F; Yu Q; Yan S; Zhang Z; Vangavaragu JR; Chen D; Yan SF; Yan SS
    Aging Cell; 2021 May; 20(5):e13368. PubMed ID: 33951271
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A NH2 tau fragment targets neuronal mitochondria at AD synapses: possible implications for neurodegeneration.
    Amadoro G; Corsetti V; Stringaro A; Colone M; D'Aguanno S; Meli G; Ciotti M; Sancesario G; Cattaneo A; Bussani R; Mercanti D; Calissano P
    J Alzheimers Dis; 2010; 21(2):445-70. PubMed ID: 20571215
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease.
    Reddy PH
    Brain Res; 2011 Sep; 1415():136-48. PubMed ID: 21872849
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloid beta-mediated KIF5A deficiency disrupts anterograde axonal mitochondrial movement.
    Wang Q; Tian J; Chen H; Du H; Guo L
    Neurobiol Dis; 2019 Jul; 127():410-418. PubMed ID: 30923004
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction between NH(2)-tau fragment and Aβ in Alzheimer's disease mitochondria contributes to the synaptic deterioration.
    Amadoro G; Corsetti V; Atlante A; Florenzano F; Capsoni S; Bussani R; Mercanti D; Calissano P
    Neurobiol Aging; 2012 Apr; 33(4):833.e1-25. PubMed ID: 21958963
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model.
    Du H; Guo L; Yan S; Sosunov AA; McKhann GM; Yan SS
    Proc Natl Acad Sci U S A; 2010 Oct; 107(43):18670-5. PubMed ID: 20937894
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
    Baek SH; Park SJ; Jeong JI; Kim SH; Han J; Kyung JW; Baik SH; Choi Y; Choi BY; Park JS; Bahn G; Shin JH; Jo DS; Lee JY; Jang CG; Arumugam TV; Kim J; Han JW; Koh JY; Cho DH; Jo DG
    J Neurosci; 2017 May; 37(20):5099-5110. PubMed ID: 28432138
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neuroprotective Effects of Ferruginol, Jatrophone, and Junicedric Acid Against Amyloid-β Injury in Hippocampal Neurons.
    Zolezzi JM; Lindsay CB; Serrano FG; Ureta RC; Theoduloz C; Schmeda-Hirschmann G; Inestrosa NC
    J Alzheimers Dis; 2018; 63(2):705-723. PubMed ID: 29660932
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of AMPA receptor trafficking at hippocampal synapses by beta-amyloid oligomers: the mitochondrial contribution.
    Rui Y; Gu J; Yu K; Hartzell HC; Zheng JQ
    Mol Brain; 2010 Mar; 3():10. PubMed ID: 20346152
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Early selective vulnerability of synapses and synaptic mitochondria in the hippocampal CA1 region of the Tg2576 mouse model of Alzheimer's disease.
    Balietti M; Giorgetti B; Casoli T; Solazzi M; Tamagnini F; Burattini C; Aicardi G; Fattoretti P
    J Alzheimers Dis; 2013; 34(4):887-96. PubMed ID: 23313923
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.
    Cai Q; Tammineni P
    J Alzheimers Dis; 2017; 57(4):1087-1103. PubMed ID: 27767992
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.