188 related articles for article (PubMed ID: 21245034)
1. Direct observation of cytosine flipping and covalent catalysis in a DNA methyltransferase.
Gerasimaitė R; Merkienė E; Klimašauskas S
Nucleic Acids Res; 2011 May; 39(9):3771-80. PubMed ID: 21245034
[TBL] [Abstract][Full Text] [Related]
2. Probing a rate-limiting step by mutational perturbation of AdoMet binding in the HhaI methyltransferase.
Merkiene E; Klimasauskas S
Nucleic Acids Res; 2005; 33(1):307-15. PubMed ID: 15653631
[TBL] [Abstract][Full Text] [Related]
3. The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI.
Shieh FK; Youngblood B; Reich NO
J Mol Biol; 2006 Sep; 362(3):516-27. PubMed ID: 16926025
[TBL] [Abstract][Full Text] [Related]
4. Structure, function, and mechanism of HhaI DNA methyltransferases.
Sankpal UT; Rao DN
Crit Rev Biochem Mol Biol; 2002; 37(3):167-97. PubMed ID: 12139442
[TBL] [Abstract][Full Text] [Related]
5. Dynamic modes of the flipped-out cytosine during HhaI methyltransferase-DNA interactions in solution.
Klimasauskas S; Szyperski T; Serva S; Wüthrich K
EMBO J; 1998 Jan; 17(1):317-24. PubMed ID: 9427765
[TBL] [Abstract][Full Text] [Related]
6. The mechanism of target base attack in DNA cytosine carbon 5 methylation.
Svedruzić ZM; Reich NO
Biochemistry; 2004 Sep; 43(36):11460-73. PubMed ID: 15350132
[TBL] [Abstract][Full Text] [Related]
7. M.HhaI binds tightly to substrates containing mismatches at the target base.
Klimasauskas S; Roberts RJ
Nucleic Acids Res; 1995 Apr; 23(8):1388-95. PubMed ID: 7753630
[TBL] [Abstract][Full Text] [Related]
8. HhaI DNA methyltransferase uses the protruding Gln237 for active flipping of its target cytosine.
Daujotyte D; Serva S; Vilkaitis G; Merkiene E; Venclovas C; Klimasauskas S
Structure; 2004 Jun; 12(6):1047-55. PubMed ID: 15274924
[TBL] [Abstract][Full Text] [Related]
9. The mechanism of DNA cytosine-5 methylation. Kinetic and mutational dissection of Hhai methyltransferase.
Vilkaitis G; Merkiene E; Serva S; Weinhold E; Klimasauskas S
J Biol Chem; 2001 Jun; 276(24):20924-34. PubMed ID: 11283006
[TBL] [Abstract][Full Text] [Related]
10. S-adenosyl-L-methionine-dependent methyl transfer: observable precatalytic intermediates during DNA cytosine methylation.
Youngblood B; Shieh FK; Buller F; Bullock T; Reich NO
Biochemistry; 2007 Jul; 46(30):8766-75. PubMed ID: 17616174
[TBL] [Abstract][Full Text] [Related]
11. A 7-Deazaadenosylaziridine Cofactor for Sequence-Specific Labeling of DNA by the DNA Cytosine-C5 Methyltransferase M.HhaI.
Kunkel F; Lurz R; Weinhold E
Molecules; 2015 Nov; 20(11):20805-22. PubMed ID: 26610450
[TBL] [Abstract][Full Text] [Related]
12. Protein-facilitated base flipping in DNA by cytosine-5-methyltransferase.
Huang N; Banavali NK; MacKerell AD
Proc Natl Acad Sci U S A; 2003 Jan; 100(1):68-73. PubMed ID: 12506195
[TBL] [Abstract][Full Text] [Related]
13. Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.
O'Gara M; Klimasauskas S; Roberts RJ; Cheng X
J Mol Biol; 1996 Sep; 261(5):634-45. PubMed ID: 8800212
[TBL] [Abstract][Full Text] [Related]
14. Engineering the DNA cytosine-5 methyltransferase reaction for sequence-specific labeling of DNA.
Lukinavicius G; Lapinaite A; Urbanaviciute G; Gerasimaite R; Klimasauskas S
Nucleic Acids Res; 2012 Dec; 40(22):11594-602. PubMed ID: 23042683
[TBL] [Abstract][Full Text] [Related]
15. Determinants of precatalytic conformational transitions in the DNA cytosine methyltransferase M.HhaI.
Matje DM; Coughlin DF; Connolly BA; Dahlquist FW; Reich NO
Biochemistry; 2011 Mar; 50(9):1465-73. PubMed ID: 21229971
[TBL] [Abstract][Full Text] [Related]
16. The coupling of tight DNA binding and base flipping: identification of a conserved structural motif in base flipping enzymes.
Estabrook RA; Lipson R; Hopkins B; Reich N
J Biol Chem; 2004 Jul; 279(30):31419-28. PubMed ID: 15143064
[TBL] [Abstract][Full Text] [Related]
17. Metadynamics simulation study on the conformational transformation of HhaI methyltransferase: an induced-fit base-flipping hypothesis.
Jin L; Ye F; Zhao D; Chen S; Zhu K; Zheng M; Jiang RW; Jiang H; Luo C
Biomed Res Int; 2014; 2014():304563. PubMed ID: 25045662
[TBL] [Abstract][Full Text] [Related]
18. Functional analysis of BamHI DNA cytosine-N4 methyltransferase.
Lindstrom WM; Malygin EG; Ovechkina LG; Zinoviev VV; Reich NO
J Mol Biol; 2003 Jan; 325(4):711-20. PubMed ID: 12507474
[TBL] [Abstract][Full Text] [Related]
19. Enzyme-promoted base flipping controls DNA methylation fidelity.
Matje DM; Zhou H; Smith DA; Neely RK; Dryden DT; Jones AC; Dahlquist FW; Reich NO
Biochemistry; 2013 Mar; 52(10):1677-85. PubMed ID: 23409782
[TBL] [Abstract][Full Text] [Related]
20. Caught in the act: visualization of an intermediate in the DNA base-flipping pathway induced by HhaI methyltransferase.
Horton JR; Ratner G; Banavali NK; Huang N; Choi Y; Maier MA; Marquez VE; MacKerell AD; Cheng X
Nucleic Acids Res; 2004; 32(13):3877-86. PubMed ID: 15273274
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]