BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

289 related articles for article (PubMed ID: 21245096)

  • 1. LATS2 is a tumor suppressor gene of malignant mesothelioma.
    Murakami H; Mizuno T; Taniguchi T; Fujii M; Ishiguro F; Fukui T; Akatsuka S; Horio Y; Hida T; Kondo Y; Toyokuni S; Osada H; Sekido Y
    Cancer Res; 2011 Feb; 71(3):873-83. PubMed ID: 21245096
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation.
    Sekido Y
    Pathol Int; 2011 Jun; 61(6):331-44. PubMed ID: 21615608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Statin suppresses Hippo pathway-inactivated malignant mesothelioma cells and blocks the YAP/CD44 growth stimulatory axis.
    Tanaka K; Osada H; Murakami-Tonami Y; Horio Y; Hida T; Sekido Y
    Cancer Lett; 2017 Jan; 385():215-224. PubMed ID: 27773750
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Co-occurring Mutations of Tumor Suppressor Genes,
    Tranchant R; Quetel L; Tallet A; Meiller C; Renier A; de Koning L; de Reynies A; Le Pimpec-Barthes F; Zucman-Rossi J; Jaurand MC; Jean D
    Clin Cancer Res; 2017 Jun; 23(12):3191-3202. PubMed ID: 28003305
    [No Abstract]   [Full Text] [Related]  

  • 5. LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade.
    Tanaka I; Osada H; Fujii M; Fukatsu A; Hida T; Horio Y; Kondo Y; Sato A; Hasegawa Y; Tsujimura T; Sekido Y
    Oncogene; 2015 Jan; 34(1):73-83. PubMed ID: 24336325
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Frequent polymorphic changes but rare tumor specific mutations of the LATS2 gene on 13q11-12 in esophageal squamous cell carcinoma.
    Ishizaki K; Fujimoto J; Kumimoto H; Nishimoto Y; Shimada Y; Shinoda M; Yamamoto T
    Int J Oncol; 2002 Nov; 21(5):1053-7. PubMed ID: 12370754
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hippo pathway gene mutations in malignant mesothelioma: revealed by RNA and targeted exon sequencing.
    Miyanaga A; Masuda M; Tsuta K; Kawasaki K; Nakamura Y; Sakuma T; Asamura H; Gemma A; Yamada T
    J Thorac Oncol; 2015 May; 10(5):844-851. PubMed ID: 25902174
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interphase fish analysis of cell cycle genes in asbestos-treated human mesothelial cells (HMC), SV40-transformed HMC (MeT-5A) and mesothelioma cells (COLO).
    Dopp E; Poser I; Papp T
    Cell Mol Biol (Noisy-le-grand); 2002; 48 Online Pub():OL271-7. PubMed ID: 12643444
    [TBL] [Abstract][Full Text] [Related]  

  • 9. YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes.
    Mizuno T; Murakami H; Fujii M; Ishiguro F; Tanaka I; Kondo Y; Akatsuka S; Toyokuni S; Yokoi K; Osada H; Sekido Y
    Oncogene; 2012 Dec; 31(49):5117-22. PubMed ID: 22286761
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer.
    Lee KH; Goan YG; Hsiao M; Lee CH; Jian SH; Lin JT; Chen YL; Lu PJ
    Exp Cell Res; 2009 Sep; 315(15):2529-38. PubMed ID: 19501585
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Putative tumor suppressor Lats2 induces apoptosis through downregulation of Bcl-2 and Bcl-x(L).
    Ke H; Pei J; Ni Z; Xia H; Qi H; Woods T; Kelekar A; Tao W
    Exp Cell Res; 2004 Aug; 298(2):329-38. PubMed ID: 15265683
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells.
    Sekido Y
    Cancer Sci; 2010 Jan; 101(1):1-6. PubMed ID: 19793348
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK.
    Poulikakos PI; Xiao GH; Gallagher R; Jablonski S; Jhanwar SC; Testa JR
    Oncogene; 2006 Sep; 25(44):5960-8. PubMed ID: 16652148
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers.
    Takahashi Y; Miyoshi Y; Takahata C; Irahara N; Taguchi T; Tamaki Y; Noguchi S
    Clin Cancer Res; 2005 Feb; 11(4):1380-5. PubMed ID: 15746036
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional inactivation of NF2/merlin in human mesothelioma.
    Thurneysen C; Opitz I; Kurtz S; Weder W; Stahel RA; Felley-Bosco E
    Lung Cancer; 2009 May; 64(2):140-7. PubMed ID: 18835652
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Frequent deletion of 3p21.1 region carrying semaphorin 3G and aberrant expression of the genes participating in semaphorin signaling in the epithelioid type of malignant mesothelioma cells.
    Yoshikawa Y; Sato A; Tsujimura T; Morinaga T; Fukuoka K; Yamada S; Murakami A; Kondo N; Matsumoto S; Okumura Y; Tanaka F; Hasegawa S; Hashimoto-Tamaoki T; Nakano T
    Int J Oncol; 2011 Dec; 39(6):1365-74. PubMed ID: 21842119
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Frequent mutations of NF2 and allelic loss from chromosome band 22q12 in malignant mesothelioma: evidence for a two-hit mechanism of NF2 inactivation.
    Cheng JQ; Lee WC; Klein MA; Cheng GZ; Jhanwar SC; Testa JR
    Genes Chromosomes Cancer; 1999 Mar; 24(3):238-42. PubMed ID: 10451704
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Beta-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion.
    Usami N; Sekido Y; Maeda O; Yamamoto K; Minna JD; Hasegawa Y; Yoshioka H; Imaizumi M; Ueda Y; Takahashi M; Shimokata K
    Oncogene; 2003 Sep; 22(39):7923-30. PubMed ID: 12970740
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Asbestos, chromosomal deletions, and tumor suppressor gene alterations in human malignant mesothelioma.
    Murthy SS; Testa JR
    J Cell Physiol; 1999 Aug; 180(2):150-7. PubMed ID: 10395284
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quinidine impairs proliferation of neurofibromatosis type 2-deficient human malignant mesothelioma cells.
    Utermark T; Alekov A; Lerche H; Abramowski V; Giovannini M; Hanemann CO
    Cancer; 2003 Apr; 97(8):1955-62. PubMed ID: 12673723
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.