355 related articles for article (PubMed ID: 21245140)
1. SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27(KIP1) through SKP2 in human leukemia cells.
Bretones G; Acosta JC; Caraballo JM; Ferrándiz N; Gómez-Casares MT; Albajar M; Blanco R; Ruiz P; Hung WC; Albero MP; Perez-Roger I; León J
J Biol Chem; 2011 Mar; 286(11):9815-25. PubMed ID: 21245140
[TBL] [Abstract][Full Text] [Related]
2. Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis.
Old JB; Kratzat S; Hoellein A; Graf S; Nilsson JA; Nilsson L; Nakayama KI; Peschel C; Cleveland JL; Keller UB
Mol Cancer Res; 2010 Mar; 8(3):353-62. PubMed ID: 20197382
[TBL] [Abstract][Full Text] [Related]
3. WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cells.
Tang Y; Simoneau AR; Liao WX; Yi G; Hope C; Liu F; Li S; Xie J; Holcombe RF; Jurnak FA; Mercola D; Hoang BH; Zi X
Mol Cancer Ther; 2009 Feb; 8(2):458-68. PubMed ID: 19174556
[TBL] [Abstract][Full Text] [Related]
4. MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27(KIP1.).
Gómez-Casares MT; García-Alegria E; López-Jorge CE; Ferrándiz N; Blanco R; Alvarez S; Vaqué JP; Bretones G; Caraballo JM; Sánchez-Bailón P; Delgado MD; Martín-Perez J; Cigudosa JC; León J
Oncogene; 2013 Apr; 32(17):2239-46. PubMed ID: 22710719
[TBL] [Abstract][Full Text] [Related]
5. Korean red ginseng extract induces proliferation to differentiation transition of human acute promyelocytic leukemia cells via MYC-SKP2-CDKN1B axis.
Jo S; Lee H; Kim S; Lee CH; Chung H
J Ethnopharmacol; 2013 Nov; 150(2):700-7. PubMed ID: 24095829
[TBL] [Abstract][Full Text] [Related]
6. Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas.
Lwin T; Hazlehurst LA; Dessureault S; Lai R; Bai W; Sotomayor E; Moscinski LC; Dalton WS; Tao J
Blood; 2007 Sep; 110(5):1631-8. PubMed ID: 17502456
[TBL] [Abstract][Full Text] [Related]
7. c-myc and skp2 coordinate p27 degradation, vascular smooth muscle proliferation, and neointima formation induced by the parathyroid hormone-related protein.
Sicari BM; Troxell R; Salim F; Tanwir M; Takane KK; Fiaschi-Taesch N
Endocrinology; 2012 Feb; 153(2):861-72. PubMed ID: 22210745
[TBL] [Abstract][Full Text] [Related]
8. Altered expression of Skp2, c-Myc and p27 proteins but not mRNA after H. pylori eradication in chronic gastritis.
Kim SS; Meitner P; Konkin TA; Cho YS; Resnick MB; Moss SF
Mod Pathol; 2006 Jan; 19(1):49-58. PubMed ID: 16118628
[TBL] [Abstract][Full Text] [Related]
9. p27(Kip1) signaling: Transcriptional and post-translational regulation.
Hnit SS; Xie C; Yao M; Holst J; Bensoussan A; De Souza P; Li Z; Dong Q
Int J Biochem Cell Biol; 2015 Nov; 68():9-14. PubMed ID: 26279144
[TBL] [Abstract][Full Text] [Related]
10. High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycle.
Caraballo JM; Acosta JC; Cortés MA; Albajar M; Gómez-Casares MT; Batlle-López A; Cuadrado MA; Onaindia A; Bretones G; Llorca J; Piris MA; Colomer D; León J
Oncotarget; 2014 Jul; 5(13):4694-708. PubMed ID: 25051361
[TBL] [Abstract][Full Text] [Related]
11. Downregulation of Skp2 and p27/Kip1 synergistically induces apoptosis in T98G glioblastoma cells.
Lee SH; McCormick F
J Mol Med (Berl); 2005 Apr; 83(4):296-307. PubMed ID: 15605273
[TBL] [Abstract][Full Text] [Related]
12. BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells.
Andreu EJ; Lledó E; Poch E; Ivorra C; Albero MP; Martínez-Climent JA; Montiel-Duarte C; Rifón J; Pérez-Calvo J; Arbona C; Prósper F; Pérez-Roger I
Cancer Res; 2005 Apr; 65(8):3264-72. PubMed ID: 15833859
[TBL] [Abstract][Full Text] [Related]
13. Sulforaphane down-regulates SKP2 to stabilize p27(KIP1) for inducing antiproliferation in human colon adenocarcinoma cells.
Chung YK; Chi-Hung Or R; Lu CH; Ouyang WT; Yang SY; Chang CC
J Biosci Bioeng; 2015 Jan; 119(1):35-42. PubMed ID: 25070589
[TBL] [Abstract][Full Text] [Related]
14. ERK-dependent downregulation of Skp2 reduces Myc activity with HGF, leading to inhibition of cell proliferation through a decrease in Id1 expression.
Li X; Bian Y; Takizawa Y; Hashimoto T; Ikoma T; Tanaka J; Kitamura N; Inagaki Y; Komada M; Tanaka T
Mol Cancer Res; 2013 Nov; 11(11):1437-47. PubMed ID: 24177224
[TBL] [Abstract][Full Text] [Related]
15. Skp2 is necessary for Myc-induced keratinocyte proliferation but dispensable for Myc oncogenic activity in the oral epithelium.
Sistrunk C; Macias E; Nakayama K; Kim Y; Rodriguez-Puebla ML
Am J Pathol; 2011 Jun; 178(6):2470-7. PubMed ID: 21641375
[TBL] [Abstract][Full Text] [Related]
16. Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells.
Bhatt KV; Hu R; Spofford LS; Aplin AE
Oncogene; 2007 Feb; 26(7):1056-66. PubMed ID: 16924241
[TBL] [Abstract][Full Text] [Related]
17. Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells.
Chen XM; Xie XB; Zhao Q; Wang F; Bai Y; Yin JQ; Jiang H; Xie XL; Jia Q; Huang G
Mol Med Rep; 2015 Jan; 11(1):105-12. PubMed ID: 25333250
[TBL] [Abstract][Full Text] [Related]
18. SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma.
Evans L; Chen L; Milazzo G; Gherardi S; Perini G; Willmore E; Newell DR; Tweddle DA
Cancer Lett; 2015 Jul; 363(1):37-45. PubMed ID: 25843293
[TBL] [Abstract][Full Text] [Related]
19. GATA-2/estrogen receptor chimera regulates cytokine-dependent growth of hematopoietic cells through accumulation of p21(WAF1) and p27(Kip1) proteins.
Ezoe S; Matsumura I; Nakata S; Gale K; Ishihara K; Minegishi N; Machii T; Kitamura T; Yamamoto M; Enver T; Kanakura Y
Blood; 2002 Nov; 100(10):3512-20. PubMed ID: 12393444
[TBL] [Abstract][Full Text] [Related]
20. Definition of a Skp2-c-Myc Pathway to Expand Human Beta-cells.
Tiwari S; Roel C; Tanwir M; Wills R; Perianayagam N; Wang P; Fiaschi-Taesch NM
Sci Rep; 2016 Jul; 6():28461. PubMed ID: 27380896
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
