108 related articles for article (PubMed ID: 21246697)
1. Gephyronic acid, a missing link between polyketide inhibitors of eukaryotic protein synthesis (part II): Total synthesis of gephyronic acid.
Anderl T; Nicolas L; Münkemer J; Baro A; Sasse F; Steinmetz H; Jansen R; Höfle G; Taylor RE; Laschat S
Angew Chem Int Ed Engl; 2011 Jan; 50(4):942-5. PubMed ID: 21246697
[No Abstract] [Full Text] [Related]
2. Gephyronic acid, a missing link between polyketide inhibitors of eukaryotic protein synthesis (part I): Structural revision and stereochemical assignment of gephyronic acid.
Nicolas L; Anderl T; Sasse F; Steinmetz H; Jansen R; Höfle G; Laschat S; Taylor RE
Angew Chem Int Ed Engl; 2011 Jan; 50(4):938-41. PubMed ID: 21246696
[No Abstract] [Full Text] [Related]
3. Elucidation of gephyronic acid biosynthetic pathway revealed unexpected SAM-dependent methylations.
Young J; Stevens DC; Carmichael R; Tan J; Rachid S; Boddy CN; Müller R; Taylor RE
J Nat Prod; 2013 Dec; 76(12):2269-76. PubMed ID: 24298873
[TBL] [Abstract][Full Text] [Related]
4. Tedanolide and the evolution of polyketide inhibitors of eukaryotic protein synthesis.
Taylor RE
Nat Prod Rep; 2008 Oct; 25(5):854-61. PubMed ID: 18820754
[TBL] [Abstract][Full Text] [Related]
5. Gephyronic acid, a novel inhibitor of eukaryotic protein synthesis from Archangium gephyra (myxobacteria). Production, isolation, physico-chemical and biological properties, and mechanism of action.
Sasse F; Steinmetz H; Höfle G; Reichenbach H
J Antibiot (Tokyo); 1995 Jan; 48(1):21-5. PubMed ID: 7868385
[TBL] [Abstract][Full Text] [Related]
6. Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase.
Dodge GJ; Ronnow D; Taylor RE; Smith JL
ACS Chem Biol; 2018 Sep; 13(9):2699-2707. PubMed ID: 30179448
[TBL] [Abstract][Full Text] [Related]
7. α-Methylation follows condensation in the gephyronic acid modular polyketide synthase.
Wagner DT; Stevens DC; Mehaffey MR; Manion HR; Taylor RE; Brodbelt JS; Keatinge-Clay AT
Chem Commun (Camb); 2016 Jul; 52(57):8822-5. PubMed ID: 27346052
[TBL] [Abstract][Full Text] [Related]
8. Investigations on the mode of action of gephyronic acid, an inhibitor of eukaryotic protein translation from myxobacteria.
Muthukumar Y; Münkemer J; Mathieu D; Richter C; Schwalbe H; Steinmetz H; Kessler W; Reichelt J; Beutling U; Frank R; Büssow K; van den Heuvel J; Brönstrup M; Taylor RE; Laschat S; Sasse F
PLoS One; 2018; 13(7):e0201605. PubMed ID: 30063768
[TBL] [Abstract][Full Text] [Related]
9. Stereochemical determination of thuggacins A-C, highly active antibiotics from the myxobacterium Sorangium cellulosum.
Bock M; Buntin K; Müller R; Kirschning A
Angew Chem Int Ed Engl; 2008; 47(12):2308-11. PubMed ID: 18275054
[No Abstract] [Full Text] [Related]
10. Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD.
Strancar K; Blanot D; Gobec S
Bioorg Med Chem Lett; 2006 Jan; 16(2):343-8. PubMed ID: 16271472
[TBL] [Abstract][Full Text] [Related]
11. Synthesis of simplified tedanolide analogues--connecting tedanolide to myriaporone and gephyronic acid.
Diaz N; Naini A; Muthukumar Y; Sasse F; Kalesse M
ChemMedChem; 2012 May; 7(5):771-5. PubMed ID: 22383258
[TBL] [Abstract][Full Text] [Related]
12. Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH.
Watkins WJ; Chen JM; Cho A; Chong L; Collins N; Fardis M; Huang W; Hung M; Kirschberg T; Lee WA; Liu X; Thomas W; Xu J; Zeynalzadegan A; Zhang J
Bioorg Med Chem Lett; 2006 Jul; 16(13):3479-83. PubMed ID: 16621550
[TBL] [Abstract][Full Text] [Related]
13. Probing the peptidylglycine alpha-hydroxylating monooxygenase active site with novel 4-phenyl-3-butenoic acid based inhibitors.
Langella E; Pierre S; Ghattas W; Giorgi M; Réglier M; Saviano M; Esposito L; Hardré R
ChemMedChem; 2010 Sep; 5(9):1568-76. PubMed ID: 20715282
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and structure-activity relationship of aminopyrimidine IKK2 inhibitors.
Bingham AH; Davenport RJ; Fosbeary R; Gowers L; Knight RL; Lowe C; Owen DA; Parry DM; Pitt WR
Bioorg Med Chem Lett; 2008 Jun; 18(12):3622-7. PubMed ID: 18501602
[TBL] [Abstract][Full Text] [Related]
15. Non-modular polyketide synthases in myxobacteria.
Li Y; Müller R
Phytochemistry; 2009; 70(15-16):1850-7. PubMed ID: 19586645
[TBL] [Abstract][Full Text] [Related]
16. Rational design of new bifunctional inhibitors of type II dehydroquinase.
Toscano MD; Stewart KA; Coggins JR; Lapthorn AJ; Abell C
Org Biomol Chem; 2005 Sep; 3(17):3102-4. PubMed ID: 16106291
[TBL] [Abstract][Full Text] [Related]
17. Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase.
Minkkilä A; Saario SM; Käsnänen H; Leppänen J; Poso A; Nevalainen T
J Med Chem; 2008 Nov; 51(22):7057-60. PubMed ID: 18983140
[TBL] [Abstract][Full Text] [Related]
18. Phenylimidazole derivatives as specific inhibitors of bacterial enoyl-acyl carrier protein reductase FabK.
Ozawa T; Kitagawa H; Yamamoto Y; Takahata S; Iida M; Osaki Y; Yamada K
Bioorg Med Chem; 2007 Dec; 15(23):7325-36. PubMed ID: 17892940
[TBL] [Abstract][Full Text] [Related]
19. Parallel synthesis and in vitro activity of novel anthranilic hydroxamate-based inhibitors of the prostaglandin H2 synthase peroxidase activity.
Lee J; Chubb AJ; Moman E; McLoughlin BM; Sharkey CT; Kelly JG; Nolan KB; Devocelle M; Fitzgerald DJ
Org Biomol Chem; 2005 Oct; 3(20):3678-85. PubMed ID: 16211102
[TBL] [Abstract][Full Text] [Related]
20. Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222.
Rodriquez M; Terracciano S; Cini E; Settembrini G; Bruno I; Bifulco G; Taddei M; Gomez-Paloma L
Angew Chem Int Ed Engl; 2006 Jan; 45(3):423-7. PubMed ID: 16311994
[No Abstract] [Full Text] [Related]
[Next] [New Search]
