295 related articles for article (PubMed ID: 21248316)
1. An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice.
Neff CP; Zhou J; Remling L; Kuruvilla J; Zhang J; Li H; Smith DD; Swiderski P; Rossi JJ; Akkina R
Sci Transl Med; 2011 Jan; 3(66):66ra6. PubMed ID: 21248316
[TBL] [Abstract][Full Text] [Related]
2. Receptor-targeted aptamer-siRNA conjugate-directed transcriptional regulation of HIV-1.
Zhou J; Lazar D; Li H; Xia X; Satheesan S; Charlins P; O'Mealy D; Akkina R; Saayman S; Weinberg MS; Rossi JJ; Morris KV
Theranostics; 2018; 8(6):1575-1590. PubMed ID: 29556342
[TBL] [Abstract][Full Text] [Related]
3. Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice.
Zhou J; Neff CP; Liu X; Zhang J; Li H; Smith DD; Swiderski P; Aboellail T; Huang Y; Du Q; Liang Z; Peng L; Akkina R; Rossi JJ
Mol Ther; 2011 Dec; 19(12):2228-38. PubMed ID: 21952167
[TBL] [Abstract][Full Text] [Related]
4. Development of cell-type specific anti-HIV gp120 aptamers for siRNA delivery.
Zhou J; Li H; Zhang J; Piotr S; Rossi J
J Vis Exp; 2011 Jun; (52):. PubMed ID: 21730942
[TBL] [Abstract][Full Text] [Related]
5. Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 inhibition.
Zhou J; Shu Y; Guo P; Smith DD; Rossi JJ
Methods; 2011 Jun; 54(2):284-94. PubMed ID: 21256218
[TBL] [Abstract][Full Text] [Related]
6. Therapeutic potential of aptamer-siRNA conjugates for treatment of HIV-1.
Zhou J; Rossi JJ
BioDrugs; 2012 Dec; 26(6):393-400. PubMed ID: 23046156
[TBL] [Abstract][Full Text] [Related]
7. Cell-type-specific aptamer and aptamer-small interfering RNA conjugates for targeted human immunodeficiency virus type 1 therapy.
Zhou J; Rossi J
J Investig Med; 2014 Oct; 62(7):914-9. PubMed ID: 25118114
[TBL] [Abstract][Full Text] [Related]
8. HIV-1 infection and CD4 T cell depletion in the humanized Rag2-/-gamma c-/- (RAG-hu) mouse model.
Berges BK; Wheat WH; Palmer BE; Connick E; Akkina R
Retrovirology; 2006 Nov; 3():76. PubMed ID: 17078891
[TBL] [Abstract][Full Text] [Related]
9. Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge.
Zhou J; Neff CP; Swiderski P; Li H; Smith DD; Aboellail T; Remling-Mulder L; Akkina R; Rossi JJ
Mol Ther; 2013 Jan; 21(1):192-200. PubMed ID: 23164935
[TBL] [Abstract][Full Text] [Related]
10. Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy.
Zhou J; Li H; Li S; Zaia J; Rossi JJ
Mol Ther; 2008 Aug; 16(8):1481-9. PubMed ID: 18461053
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of HIV-1 protease expression in T cells owing to DNA aptamer-mediated specific delivery of siRNA.
Zhu Q; Shibata T; Kabashima T; Kai M
Eur J Med Chem; 2012 Oct; 56():396-9. PubMed ID: 22907035
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras.
Wheeler LA; Trifonova R; Vrbanac V; Basar E; McKernan S; Xu Z; Seung E; Deruaz M; Dudek T; Einarsson JI; Yang L; Allen TM; Luster AD; Tager AM; Dykxhoorn DM; Lieberman J
J Clin Invest; 2011 Jun; 121(6):2401-12. PubMed ID: 21576818
[TBL] [Abstract][Full Text] [Related]
13. Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells.
Zhou J; Swiderski P; Li H; Zhang J; Neff CP; Akkina R; Rossi JJ
Nucleic Acids Res; 2009 May; 37(9):3094-109. PubMed ID: 19304999
[TBL] [Abstract][Full Text] [Related]
14. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice.
Kumar P; Ban HS; Kim SS; Wu H; Pearson T; Greiner DL; Laouar A; Yao J; Haridas V; Habiro K; Yang YG; Jeong JH; Lee KY; Kim YH; Kim SW; Peipp M; Fey GH; Manjunath N; Shultz LD; Lee SK; Shankar P
Cell; 2008 Aug; 134(4):577-86. PubMed ID: 18691745
[TBL] [Abstract][Full Text] [Related]
15. Aptamer-targeted RNAi for HIV-1 therapy.
Zhou J; Rossi JJ
Methods Mol Biol; 2011; 721():355-71. PubMed ID: 21431697
[TBL] [Abstract][Full Text] [Related]
16. Cell-specific RNA aptamer against human CCR5 specifically targets HIV-1 susceptible cells and inhibits HIV-1 infectivity.
Zhou J; Satheesan S; Li H; Weinberg MS; Morris KV; Burnett JC; Rossi JJ
Chem Biol; 2015 Mar; 22(3):379-90. PubMed ID: 25754473
[TBL] [Abstract][Full Text] [Related]
17. Incorporation of aptamers in the terminal loop of shRNAs yields an effective and novel combinatorial targeting strategy.
Pang KM; Castanotto D; Li H; Scherer L; Rossi JJ
Nucleic Acids Res; 2018 Jan; 46(1):e6. PubMed ID: 29077949
[TBL] [Abstract][Full Text] [Related]
18. In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice.
Palmer BE; Neff CP; Lecureux J; Ehler A; Dsouza M; Remling-Mulder L; Korman AJ; Fontenot AP; Akkina R
J Immunol; 2013 Jan; 190(1):211-9. PubMed ID: 23209326
[TBL] [Abstract][Full Text] [Related]
19. Glycosylphosphatidylinositol-Anchored Anti-HIV scFv Efficiently Protects CD4 T Cells from HIV-1 Infection and Deletion in hu-PBL Mice.
Ye C; Wang W; Cheng L; Li G; Wen M; Wang Q; Zhang Q; Li D; Zhou P; Su L
J Virol; 2017 Feb; 91(3):. PubMed ID: 27881659
[TBL] [Abstract][Full Text] [Related]
20. Mucosal transmission of R5 and X4 tropic HIV-1 via vaginal and rectal routes in humanized Rag2-/- gammac -/- (RAG-hu) mice.
Berges BK; Akkina SR; Folkvord JM; Connick E; Akkina R
Virology; 2008 Apr; 373(2):342-51. PubMed ID: 18207484
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
