BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

465 related articles for article (PubMed ID: 21249202)

  • 1. Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice.
    Akundi RS; Huang Z; Eason J; Pandya JD; Zhi L; Cass WA; Sullivan PG; Büeler H
    PLoS One; 2011 Jan; 6(1):e16038. PubMed ID: 21249202
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice.
    Kitada T; Pisani A; Porter DR; Yamaguchi H; Tscherter A; Martella G; Bonsi P; Zhang C; Pothos EN; Shen J
    Proc Natl Acad Sci U S A; 2007 Jul; 104(27):11441-6. PubMed ID: 17563363
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death.
    Gandhi S; Wood-Kaczmar A; Yao Z; Plun-Favreau H; Deas E; Klupsch K; Downward J; Latchman DS; Tabrizi SJ; Wood NW; Duchen MR; Abramov AY
    Mol Cell; 2009 Mar; 33(5):627-38. PubMed ID: 19285945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dopamine induced neurodegeneration in a PINK1 model of Parkinson's disease.
    Gandhi S; Vaarmann A; Yao Z; Duchen MR; Wood NW; Abramov AY
    PLoS One; 2012; 7(5):e37564. PubMed ID: 22662171
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparative analysis of Parkinson's disease-associated genes in mice reveals altered survival and bioenergetics of Parkin-deficient dopamine neurons.
    Giguère N; Pacelli C; Saumure C; Bourque MJ; Matheoud D; Levesque D; Slack RS; Park DS; Trudeau LÉ
    J Biol Chem; 2018 Jun; 293(25):9580-9593. PubMed ID: 29700116
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress.
    Gautier CA; Kitada T; Shen J
    Proc Natl Acad Sci U S A; 2008 Aug; 105(32):11364-9. PubMed ID: 18687901
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of PINK1 causes age-dependent decrease of dopamine release and mitochondrial dysfunction.
    Zhi L; Qin Q; Muqeem T; Seifert EL; Liu W; Zheng S; Li C; Zhang H
    Neurobiol Aging; 2019 Mar; 75():1-10. PubMed ID: 30504091
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress.
    Huang E; Qu D; Huang T; Rizzi N; Boonying W; Krolak D; Ciana P; Woulfe J; Klein C; Slack RS; Figeys D; Park DS
    Nat Commun; 2017 Nov; 8(1):1399. PubMed ID: 29123128
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice: insights into mechanisms of familial Parkinson's disease.
    Triplett JC; Zhang Z; Sultana R; Cai J; Klein JB; Büeler H; Butterfield DA
    J Neurochem; 2015 Jun; 133(5):750-65. PubMed ID: 25626353
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of mitochondrial permeability transition pore by PINK1.
    Gautier CA; Giaime E; Caballero E; Núñez L; Song Z; Chan D; Villalobos C; Shen J
    Mol Neurodegener; 2012 May; 7():22. PubMed ID: 22630785
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration.
    Gispert S; Ricciardi F; Kurz A; Azizov M; Hoepken HH; Becker D; Voos W; Leuner K; Müller WE; Kudin AP; Kunz WS; Zimmermann A; Roeper J; Wenzel D; Jendrach M; García-Arencíbia M; Fernández-Ruiz J; Huber L; Rohrer H; Barrera M; Reichert AS; Rüb U; Chen A; Nussbaum RL; Auburger G
    PLoS One; 2009 Jun; 4(6):e5777. PubMed ID: 19492057
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance.
    Heeman B; Van den Haute C; Aelvoet SA; Valsecchi F; Rodenburg RJ; Reumers V; Debyser Z; Callewaert G; Koopman WJ; Willems PH; Baekelandt V
    J Cell Sci; 2011 Apr; 124(Pt 7):1115-25. PubMed ID: 21385841
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PINK1 positively regulates IL-1β-mediated signaling through Tollip and IRAK1 modulation.
    Lee HJ; Chung KC
    J Neuroinflammation; 2012 Dec; 9():271. PubMed ID: 23244239
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects.
    Amo T; Sato S; Saiki S; Wolf AM; Toyomizu M; Gautier CA; Shen J; Ohta S; Hattori N
    Neurobiol Dis; 2011 Jan; 41(1):111-8. PubMed ID: 20817094
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of Pink1 modulates synaptic mitochondrial bioenergetics in the rat striatum prior to motor symptoms: concomitant complex I respiratory defects and increased complex II-mediated respiration.
    Stauch KL; Villeneuve LM; Purnell PR; Ottemann BM; Emanuel K; Fox HS
    Proteomics Clin Appl; 2016 Dec; 10(12):1205-1217. PubMed ID: 27568932
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutant PINK1 upregulates tyrosine hydroxylase and dopamine levels, leading to vulnerability of dopaminergic neurons.
    Zhou ZD; Refai FS; Xie SP; Ng SH; Chan CH; Ho PG; Zhang XD; Lim TM; Tan EK
    Free Radic Biol Med; 2014 Mar; 68():220-33. PubMed ID: 24374372
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nitric oxide induction of Parkin translocation in PTEN-induced putative kinase 1 (PINK1) deficiency: functional role of neuronal nitric oxide synthase during mitophagy.
    Han JY; Kang MJ; Kim KH; Han PL; Kim HS; Ha JY; Son JH
    J Biol Chem; 2015 Apr; 290(16):10325-35. PubMed ID: 25716315
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increased glutamate transmission onto dorsal striatum spiny projection neurons in Pink1 knockout rats.
    Creed RB; Roberts RC; Farmer CB; McMahon LL; Goldberg MS
    Neurobiol Dis; 2021 Mar; 150():105246. PubMed ID: 33387634
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PINK1-Parkin signaling in Parkinson's disease: Lessons from Drosophila.
    Imai Y
    Neurosci Res; 2020 Oct; 159():40-46. PubMed ID: 32035987
    [TBL] [Abstract][Full Text] [Related]  

  • 20. N-degron-mediated degradation and regulation of mitochondrial PINK1 kinase.
    Eldeeb MA; Ragheb MA
    Curr Genet; 2020 Aug; 66(4):693-701. PubMed ID: 32157382
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.