BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 21250752)

  • 1. Atropisomerism observed in indometacin derivatives.
    Takahashi H; Wakamatsu S; Tabata H; Oshitari T; Harada A; Inoue K; Natsugari H
    Org Lett; 2011 Feb; 13(4):760-3. PubMed ID: 21250752
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conformation and atropisomeric properties of indometacin derivatives.
    Wakamatsu S; Takahashi Y; Tabata H; Oshitari T; Tani N; Azumaya I; Katsumoto Y; Tanaka T; Hosoi S; Natsugari H; Takahashi H
    Chemistry; 2013 May; 19(22):7056-63. PubMed ID: 23576314
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of indomethacin analogues that inhibit P-glycoprotein and/or multidrug resistant protein without COX inhibitory activity.
    Arisawa M; Kasaya Y; Obata T; Sasaki T; Nakamura T; Araki T; Yamamoto K; Sasaki A; Yamano A; Ito M; Abe H; Ito Y; Shuto S
    J Med Chem; 2012 Sep; 55(18):8152-63. PubMed ID: 22916727
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study.
    Abdel-Aziz AA; ElTahir KE; Asiri YA
    Eur J Med Chem; 2011 May; 46(5):1648-55. PubMed ID: 21388719
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors.
    Kalgutkar AS; Marnett AB; Crews BC; Remmel RP; Marnett LJ
    J Med Chem; 2000 Jul; 43(15):2860-70. PubMed ID: 10956194
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of carbaborane derivatives of indomethacin as cyclooxygenase inhibitors.
    Scholz M; Blobaum AL; Marnett LJ; Hey-Hawkins E
    Bioorg Med Chem; 2011 May; 19(10):3242-8. PubMed ID: 21524587
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Perspective assessment of COX-1 and COX-2 selectivity of nonsteroidal anti-inflammatory drugs from clinical practice: use of genetic function approximation.
    Zambre AP; Ganure AL; Shinde DB; Kulkarni VM
    J Chem Inf Model; 2007; 47(2):635-43. PubMed ID: 17256838
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.
    Tewari AK; Singh VP; Yadav P; Gupta G; Singh A; Goel RK; Shinde P; Mohan CG
    Bioorg Chem; 2014 Oct; 56():8-15. PubMed ID: 24893208
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and synthesis of 2-phenoxynicotinic acid hydrazides as anti-inflammatory and analgesic agents.
    Moradi A; Navidpour L; Amini M; Sadeghian H; Shadnia H; Firouzi O; Miri R; Ebrahimi SE; Abdollahi M; Zahmatkesh MH; Shafiee A
    Arch Pharm (Weinheim); 2010 Sep; 343(9):509-18. PubMed ID: 20806271
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.
    Praveen Rao PN; Amini M; Li H; Habeeb AG; Knaus EE
    J Med Chem; 2003 Nov; 46(23):4872-82. PubMed ID: 14584938
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rational design, synthesis and evaluation of chromone-indole and chromone-pyrazole based conjugates: identification of a lead for anti-inflammatory drug.
    Shaveta ; Singh A; Kaur M; Sharma S; Bhatti R; Singh P
    Eur J Med Chem; 2014 Apr; 77():185-92. PubMed ID: 24631898
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and biological evaluation of substituted 2-alkylthio-1,5-diarylimidazoles as selective COX-2 inhibitors.
    Navidpour L; Shadnia H; Shafaroodi H; Amini M; Dehpour AR; Shafiee A
    Bioorg Med Chem; 2007 Mar; 15(5):1976-82. PubMed ID: 17258905
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New indomethacin analogs as selective COX-2 inhibitors: Synthesis, COX-1/2 inhibitory activity, anti-inflammatory, ulcerogenicity, histopathological, and docking studies.
    Abdellatif KRA; Abdelall EKA; Elshemy HAH; El-Nahass ES; Abdel-Fattah MM; Abdelgawad YYM
    Arch Pharm (Weinheim); 2021 Apr; 354(4):e2000328. PubMed ID: 33314237
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of 2-methyl-3-indolylacetic derivatives as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 without gastric damage.
    Perissutti E; Fiorino F; Renner C; Severino B; Roviezzo F; Sautebin L; Rossi A; Cirino G; Santagada V; Caliendo G
    J Med Chem; 2006 Dec; 49(26):7774-80. PubMed ID: 17181159
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of 2,3-diaryl-1,3-thiazolidine-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors.
    Zarghi A; Najafnia L; Daraee B; Dadrass OG; Hedayati M
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5634-7. PubMed ID: 17822894
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of linear phenylethynylbenzenesulfonamide regioisomers as cyclooxygenase-1/-2 (COX-1/-2) inhibitors.
    Anana R; Rao PN; Chen QH; Knaus EE
    Bioorg Med Chem; 2006 Aug; 14(15):5259-65. PubMed ID: 16635574
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3-methyl-2-phenyl-1-substituted-indole derivatives as indomethacin analogs: design, synthesis and biological evaluation as potential anti-inflammatory and analgesic agents.
    Abdellatif KR; Lamie PF; Omar HA
    J Enzyme Inhib Med Chem; 2016; 31(2):318-24. PubMed ID: 25798690
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thiazole analogues of the NSAID indomethacin as selective COX-2 inhibitors.
    Woods KW; McCroskey RW; Michaelides MR; Wada CK; Hulkower KI; Bell RL
    Bioorg Med Chem Lett; 2001 May; 11(10):1325-8. PubMed ID: 11392547
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and effects on the COX-1 and COX-2 activity in human whole blood ex vivo of derivatives containing the [1]benzothienol-[3, 2-d]pyrimidin-4-one heterocyclic system.
    Santagati A; Granata G; Marrazzo A; Santagati M
    Arch Pharm (Weinheim); 2003 Sep; 336(9):429-35. PubMed ID: 14528491
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of glycolamide esters of indomethacin as potential cyclooxygenase-2 (COX-2) inhibitors.
    Khanna S; Madan M; Vangoori A; Banerjee R; Thaimattam R; Jafar Sadik Basha SK; Ramesh M; Casturi SR; Pal M
    Bioorg Med Chem; 2006 Jul; 14(14):4820-33. PubMed ID: 16581252
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.