184 related articles for article (PubMed ID: 21252065)
1. Platelet protein kinase C-theta deficiency with human RUNX1 mutation: PRKCQ is a transcriptional target of RUNX1.
Jalagadugula G; Mao G; Kaur G; Dhanasekaran DN; Rao AK
Arterioscler Thromb Vasc Biol; 2011 Apr; 31(4):921-7. PubMed ID: 21252065
[TBL] [Abstract][Full Text] [Related]
2. Mechanism of platelet factor 4 (PF4) deficiency with RUNX1 haplodeficiency: RUNX1 is a transcriptional regulator of PF4.
Aneja K; Jalagadugula G; Mao G; Singh A; Rao AK
J Thromb Haemost; 2011 Feb; 9(2):383-91. PubMed ID: 21129147
[TBL] [Abstract][Full Text] [Related]
3. Dysregulation of PLDN (pallidin) is a mechanism for platelet dense granule deficiency in RUNX1 haplodeficiency.
Mao GF; Goldfinger LE; Fan DC; Lambert MP; Jalagadugula G; Freishtat R; Rao AK
J Thromb Haemost; 2017 Apr; 15(4):792-801. PubMed ID: 28075530
[TBL] [Abstract][Full Text] [Related]
4. RUNX1/core binding factor A2 regulates platelet 12-lipoxygenase gene (ALOX12): studies in human RUNX1 haplodeficiency.
Kaur G; Jalagadugula G; Mao G; Rao AK
Blood; 2010 Apr; 115(15):3128-35. PubMed ID: 20181616
[TBL] [Abstract][Full Text] [Related]
5. Regulation of platelet myosin light chain (MYL9) by RUNX1: implications for thrombocytopenia and platelet dysfunction in RUNX1 haplodeficiency.
Jalagadugula G; Mao G; Kaur G; Goldfinger LE; Dhanasekaran DN; Rao AK
Blood; 2010 Dec; 116(26):6037-45. PubMed ID: 20876458
[TBL] [Abstract][Full Text] [Related]
6. Defective RAB1B-related megakaryocytic ER-to-Golgi transport in RUNX1 haplodeficiency: impact on von Willebrand factor.
Jalagadugula G; Goldfinger LE; Mao G; Lambert MP; Rao AK
Blood Adv; 2018 Apr; 2(7):797-806. PubMed ID: 29632235
[TBL] [Abstract][Full Text] [Related]
7. Association of CBFA2 mutation with decreased platelet PKC-theta and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in GPIIb-IIIa activation.
Sun L; Mao G; Rao AK
Blood; 2004 Feb; 103(3):948-54. PubMed ID: 14525764
[TBL] [Abstract][Full Text] [Related]
8. Transcription Factor RUNX1 Regulates Platelet
Mao G; Songdej N; Voora D; Goldfinger LE; Del Carpio-Cano FE; Myers RA; Rao AK
Circulation; 2017 Sep; 136(10):927-939. PubMed ID: 28676520
[TBL] [Abstract][Full Text] [Related]
9. RUNX1, but not its familial platelet disorder mutants, synergistically activates PF4 gene expression in combination with ETS family proteins.
Okada Y; Watanabe M; Nakai T; Kamikawa Y; Shimizu M; Fukuhara Y; Yonekura M; Matsuura E; Hoshika Y; Nagai R; Aird WC; Doi T
J Thromb Haemost; 2013 Sep; 11(9):1742-50. PubMed ID: 23848403
[TBL] [Abstract][Full Text] [Related]
10. Defective acid hydrolase secretion in RUNX1 haplodeficiency: Evidence for a global platelet secretory defect.
Rao AK; Poncz M
Haemophilia; 2017 Sep; 23(5):784-792. PubMed ID: 28662545
[TBL] [Abstract][Full Text] [Related]
11. Mechanisms underlying platelet function defect in a pedigree with familial platelet disorder with a predisposition to acute myelogenous leukemia: potential role for candidate RUNX1 targets.
Glembotsky AC; Bluteau D; Espasandin YR; Goette NP; Marta RF; Marin Oyarzun CP; Korin L; Lev PR; Laguens RP; Molinas FC; Raslova H; Heller PG
J Thromb Haemost; 2014 May; 12(5):761-72. PubMed ID: 24606315
[TBL] [Abstract][Full Text] [Related]
12. Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription.
Maicas M; Vázquez I; Vicente C; García-Sánchez MA; Marcotegui N; Urquiza L; Calasanz MJ; Odero MD
Oncogene; 2013 Apr; 32(16):2069-78. PubMed ID: 22689058
[TBL] [Abstract][Full Text] [Related]
13. Enrichment of FLI1 and RUNX1 mutations in families with excessive bleeding and platelet dense granule secretion defects.
Stockley J; Morgan NV; Bem D; Lowe GC; Lordkipanidzé M; Dawood B; Simpson MA; Macfarlane K; Horner K; Leo VC; Talks K; Motwani J; Wilde JT; Collins PW; Makris M; Watson SP; Daly ME;
Blood; 2013 Dec; 122(25):4090-3. PubMed ID: 24100448
[TBL] [Abstract][Full Text] [Related]
14. Regulation of MDR1 promoter activity in human breast carcinoma cells by protein kinase C isozymes alpha and theta.
Gill PK; Gescher A; Gant TW
Eur J Biochem; 2001 Aug; 268(15):4151-7. PubMed ID: 11488907
[TBL] [Abstract][Full Text] [Related]
15. Defective RAB31-mediated megakaryocytic early endosomal trafficking of VWF, EGFR, and M6PR in RUNX1 deficiency.
Jalagadugula G; Mao G; Goldfinger LE; Wurtzel J; Del Carpio-Cano F; Lambert MP; Estevez B; French DL; Poncz M; Rao AK
Blood Adv; 2022 Sep; 6(17):5100-5112. PubMed ID: 35839075
[TBL] [Abstract][Full Text] [Related]
16. The leukemia associated ETO nuclear repressor gene is regulated by the GATA-1 transcription factor in erythroid/megakaryocytic cells.
Ajore R; Dhanda RS; Gullberg U; Olsson I
BMC Mol Biol; 2010 May; 11():38. PubMed ID: 20487545
[TBL] [Abstract][Full Text] [Related]
17. Downregulation of TREM-like transcript-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia.
Glembotsky AC; Sliwa D; Bluteau D; Balayn N; Marin Oyarzún CP; Raimbault A; Bordas M; Droin N; Pirozhkova I; Washington V; Goette NP; Marta RF; Favier R; Raslova H; Heller PG
Haematologica; 2019 Jun; 104(6):1244-1255. PubMed ID: 30545930
[TBL] [Abstract][Full Text] [Related]
18. Altered platelet-megakaryocyte endocytosis and trafficking of albumin and fibrinogen in RUNX1 haplodeficiency.
Del Carpio-Cano F; Mao G; Goldfinger LE; Wurtzel J; Guan L; Alam MA; Lee K; Poncz M; Rao AK
Blood Adv; 2024 Apr; 8(7):1699-1714. PubMed ID: 38330198
[TBL] [Abstract][Full Text] [Related]
19. A potential role for protein kinase C-epsilon in regulating megakaryocytic lineage commitment.
Racke FK; Wang D; Zaidi Z; Kelley J; Visvader J; Soh JW; Goldfarb AN
J Biol Chem; 2001 Jan; 276(1):522-8. PubMed ID: 11016926
[TBL] [Abstract][Full Text] [Related]
20. Transcriptional Auto-Regulation of RUNX1 P1 Promoter.
Martinez M; Hinojosa M; Trombly D; Morin V; Stein J; Stein G; Javed A; Gutierrez SE
PLoS One; 2016; 11(2):e0149119. PubMed ID: 26901859
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
