These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

404 related articles for article (PubMed ID: 21252228)

  • 21. Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells.
    Vogiatzi T; Xilouri M; Vekrellis K; Stefanis L
    J Biol Chem; 2008 Aug; 283(35):23542-56. PubMed ID: 18566453
    [TBL] [Abstract][Full Text] [Related]  

  • 22. α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson's disease.
    Di Maio R; Barrett PJ; Hoffman EK; Barrett CW; Zharikov A; Borah A; Hu X; McCoy J; Chu CT; Burton EA; Hastings TG; Greenamyre JT
    Sci Transl Med; 2016 Jun; 8(342):342ra78. PubMed ID: 27280685
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The Parkinson disease protein α-synuclein inhibits autophagy.
    Winslow AR; Rubinsztein DC
    Autophagy; 2011 Apr; 7(4):429-31. PubMed ID: 21157184
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models.
    Zhu Q; Zhuang XX; Chen JY; Yuan NN; Chen Y; Cai CZ; Tan JQ; Su HX; Lu JH
    Phytomedicine; 2021 Jul; 87():153578. PubMed ID: 34038839
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Phosphorylation of α-synuclein protein at Ser-129 reduces neuronal dysfunction by lowering its membrane binding property in Caenorhabditis elegans.
    Kuwahara T; Tonegawa R; Ito G; Mitani S; Iwatsubo T
    J Biol Chem; 2012 Mar; 287(10):7098-109. PubMed ID: 22232559
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Intracellular delivery of Parkin rescues neurons from accumulation of damaged mitochondria and pathological α-synuclein.
    Chung E; Choi Y; Park J; Nah W; Park J; Jung Y; Lee J; Lee H; Park S; Hwang S; Kim S; Lee J; Min D; Jo J; Kang S; Jung M; Lee PH; Ruley HE; Jo D
    Sci Adv; 2020 May; 6(18):eaba1193. PubMed ID: 32494688
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Overexpression of human E46K mutant α-synuclein impairs macroautophagy via inactivation of JNK1-Bcl-2 pathway.
    Yan JQ; Yuan YH; Gao YN; Huang JY; Ma KL; Gao Y; Zhang WQ; Guo XF; Chen NH
    Mol Neurobiol; 2014 Oct; 50(2):685-701. PubMed ID: 24833599
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Cystatin C as a potential therapeutic mediator against Parkinson's disease via VEGF-induced angiogenesis and enhanced neuronal autophagy in neurovascular units.
    Zou J; Chen Z; Wei X; Chen Z; Fu Y; Yang X; Chen D; Wang R; Jenner P; Lu JH; Li M; Zhang Z; Tang B; Jin K; Wang Q
    Cell Death Dis; 2017 Jun; 8(6):e2854. PubMed ID: 28569795
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Proteasome inhibitor-induced autophagy in PC12 cells overexpressing A53T mutant α-synuclein.
    Lan D; Wang W; Zhuang J; Zhao Z
    Mol Med Rep; 2015 Mar; 11(3):1655-60. PubMed ID: 25434876
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Impairment of mitochondria dynamics by human A53T α-synuclein and rescue by NAP (davunetide) in a cell model for Parkinson's disease.
    Melo TQ; van Zomeren KC; Ferrari MF; Boddeke HW; Copray JC
    Exp Brain Res; 2017 Mar; 235(3):731-742. PubMed ID: 27866262
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The role of autophagy in Parkinson's disease.
    Lynch-Day MA; Mao K; Wang K; Zhao M; Klionsky DJ
    Cold Spring Harb Perspect Med; 2012 Apr; 2(4):a009357. PubMed ID: 22474616
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Human A53T α-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neurons.
    Li L; Nadanaciva S; Berger Z; Shen W; Paumier K; Schwartz J; Mou K; Loos P; Milici AJ; Dunlop J; Hirst WD
    PLoS One; 2013; 8(12):e85815. PubMed ID: 24392030
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Triptolide Promotes the Clearance of α-Synuclein by Enhancing Autophagy in Neuronal Cells.
    Hu G; Gong X; Wang L; Liu M; Liu Y; Fu X; Wang W; Zhang T; Wang X
    Mol Neurobiol; 2017 Apr; 54(3):2361-2372. PubMed ID: 26957304
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Overexpression of α-synuclein in an astrocyte cell line promotes autophagy inhibition and apoptosis.
    Erustes AG; Stefani FY; Terashima JY; Stilhano RS; Monteforte PT; da Silva Pereira GJ; Han SW; Calgarotto AK; Hsu YT; Ureshino RP; Bincoletto C; Smaili SS
    J Neurosci Res; 2018 Jan; 96(1):160-171. PubMed ID: 28573674
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant.
    Hoenen C; Gustin A; Birck C; Kirchmeyer M; Beaume N; Felten P; Grandbarbe L; Heuschling P; Heurtaux T
    PLoS One; 2016; 11(9):e0162717. PubMed ID: 27622765
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Deficiency of RAB39B Activates ER Stress-Induced Pro-apoptotic Pathway and Causes Mitochondrial Dysfunction and Oxidative Stress in Dopaminergic Neurons by Impairing Autophagy and Upregulating α-Synuclein.
    Chiu CC; Weng YH; Yeh TH; Lu JC; Chen WS; Li AH; Chen YL; Wei KC; Wang HL
    Mol Neurobiol; 2023 May; 60(5):2706-2728. PubMed ID: 36715921
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Aggregate clearance of α-synuclein in Saccharomyces cerevisiae depends more on autophagosome and vacuole function than on the proteasome.
    Petroi D; Popova B; Taheri-Talesh N; Irniger S; Shahpasandzadeh H; Zweckstetter M; Outeiro TF; Braus GH
    J Biol Chem; 2012 Aug; 287(33):27567-79. PubMed ID: 22722939
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The regulatory role of α-synuclein and parkin in neuronal cell apoptosis; possible implications for the pathogenesis of Parkinson's disease.
    Yasuda T; Mochizuki H
    Apoptosis; 2010 Nov; 15(11):1312-21. PubMed ID: 20221696
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease.
    Büeler H
    Exp Neurol; 2009 Aug; 218(2):235-46. PubMed ID: 19303005
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment.
    Poehler AM; Xiang W; Spitzer P; May VE; Meixner H; Rockenstein E; Chutna O; Outeiro TF; Winkler J; Masliah E; Klucken J
    Autophagy; 2014; 10(12):2171-92. PubMed ID: 25484190
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.