201 related articles for article (PubMed ID: 21254424)
1. Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol.
Paterson I; Naylor GJ; Gardner NM; Guzmán E; Wright AE
Chem Asian J; 2011 Feb; 6(2):459-73. PubMed ID: 21254424
[TBL] [Abstract][Full Text] [Related]
2. Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin.
Paterson I; Naylor GJ; Fujita T; Guzmán E; Wright AE
Chem Commun (Camb); 2010 Jan; 46(2):261-3. PubMed ID: 20024345
[TBL] [Abstract][Full Text] [Related]
3. Development of practical syntheses of the marine anticancer agents discodermolide and dictyostatin.
Florence GJ; Gardner NM; Paterson I
Nat Prod Rep; 2008 Apr; 25(2):342-75. PubMed ID: 18389141
[TBL] [Abstract][Full Text] [Related]
4. Total synthesis of a potent hybrid of the anticancer natural products dictyostatin and discodermolide.
Paterson I; Naylor GJ; Wright AE
Chem Commun (Camb); 2008 Oct; (38):4628-30. PubMed ID: 18815706
[TBL] [Abstract][Full Text] [Related]
5. Total synthesis and biological evaluation of potent analogues of dictyostatin: modification of the C2-C6 dienoate region.
Paterson I; Gardner NM; Guzmán E; Wright AE
Bioorg Med Chem Lett; 2008 Dec; 18(23):6268-72. PubMed ID: 18951787
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide.
Smith AB; Freeze BS; Lamarche MJ; Hirose T; Brouard I; Rucker PV; Xian M; Sundermann KF; Shaw SJ; Burlingame MA; Horwitz SB; Myles DC
Org Lett; 2005 Jan; 7(2):311-4. PubMed ID: 15646985
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and biological evaluation of a macrocyclic discodermolide/dictyostatin hybrid.
Paterson I; Gardner NM
Chem Commun (Camb); 2007 Jan; (1):49-51. PubMed ID: 17279257
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of (+)-discodermolide-paclitaxel hybrids leading to enhanced biological activity.
Smith AB; Sugasawa K; Atasoylu O; Yang CP; Horwitz SB
J Med Chem; 2011 Sep; 54(18):6319-27. PubMed ID: 21870795
[TBL] [Abstract][Full Text] [Related]
9. Discodermolide/Dictyostatin hybrids: synthesis and biological evaluation.
Shin Y; Choy N; Turner TR; Balachandran R; Madiraju C; Day BW; Curran DP
Org Lett; 2002 Dec; 4(25):4443-6. PubMed ID: 12465908
[TBL] [Abstract][Full Text] [Related]
10. Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin.
Madiraju C; Edler MC; Hamel E; Raccor BS; Balachandran R; Zhu G; Giuliano KA; Vogt A; Shin Y; Fournier JH; Fukui Y; Brückner AM; Curran DP; Day BW
Biochemistry; 2005 Nov; 44(45):15053-63. PubMed ID: 16274252
[TBL] [Abstract][Full Text] [Related]
11. The structure activity relationship of discodermolide analogues.
Shaw SJ
Mini Rev Med Chem; 2008 Mar; 8(3):276-84. PubMed ID: 18336347
[TBL] [Abstract][Full Text] [Related]
12. Total synthesis of the potent microtubule-stabilizing agent (+)-discodermolide.
Harried SS; Lee CP; Yang G; Lee TI; Myles DC
J Org Chem; 2003 Aug; 68(17):6646-60. PubMed ID: 12919029
[TBL] [Abstract][Full Text] [Related]
13. Synthetic analogues of the microtubule-stabilizing agent (+)-discodermolide: preparation and biological activity.
Gunasekera SP; Mickel SJ; Daeffler R; Niederer D; Wright AE; Linley P; Pitts T
J Nat Prod; 2004 May; 67(5):749-56. PubMed ID: 15165132
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and biological evaluation of simplified analogues of (+)-discodermolide. Additional insights on the importance of the diene, the C7 hydroxyl, and the lactone.
Smith AB; Xian M
Org Lett; 2005 Nov; 7(23):5229-32. PubMed ID: 16268545
[TBL] [Abstract][Full Text] [Related]
15. Design, total synthesis, and evaluation of C13-C14 cyclopropane analogues of (+)-discodermolide.
Smith AB; Xian M; Liu F
Org Lett; 2005 Oct; 7(21):4613-6. PubMed ID: 16209492
[TBL] [Abstract][Full Text] [Related]
16. (+)-discodermolide: a marine natural product against cancer.
De Souza MV
ScientificWorldJournal; 2004 Jun; 4():415-36. PubMed ID: 15243683
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of 10,11-dihydrodictyostatin, a potent analogue of the marine anticancer agent dictyostatin.
Paterson I; Gardner NM; Poullennec KG; Wright AE
J Nat Prod; 2008 Mar; 71(3):364-9. PubMed ID: 18081257
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues.
Burlingame MA; Shaw SJ; Sundermann KF; Zhang D; Petryka J; Mendoza E; Liu F; Myles DC; LaMarche MJ; Hirose T; Scott Freeze B; Smith AB
Bioorg Med Chem Lett; 2004 May; 14(9):2335-8. PubMed ID: 15081036
[TBL] [Abstract][Full Text] [Related]
19. Chemistry. The renaissance of natural products as drug candidates.
Paterson I; Anderson EA
Science; 2005 Oct; 310(5747):451-3. PubMed ID: 16239465
[No Abstract] [Full Text] [Related]
20. Conception, synthesis, and biological evaluation of original discodermolide analogues.
de Lemos E; Agouridas E; Sorin G; Guerreiro A; Commerçon A; Pancrazi A; Betzer JF; Lannou MI; Ardisson J
Chemistry; 2011 Aug; 17(36):10123-34. PubMed ID: 21793059
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
