BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

86 related articles for article (PubMed ID: 21256247)

  • 1. An evaluation of a Simon 2-Stage phase II clinical trial design incorporating toxicity monitoring.
    Ray HE; Rai SN
    Contemp Clin Trials; 2011 May; 32(3):428-36. PubMed ID: 21256247
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Operating characteristics of a Simon two-stage phase II clinical trial design incorporating continuous toxicity monitoring.
    Ray HE; Rai SN
    Pharm Stat; 2012; 11(2):170-6. PubMed ID: 22232063
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A strategy for dose-finding and safety monitoring based on efficacy and adverse outcomes in phase I/II clinical trials.
    Thall PF; Russell KE
    Biometrics; 1998 Mar; 54(1):251-64. PubMed ID: 9544520
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Continuous toxicity monitoring in phase II trials in oncology.
    Ivanova A; Qaqish BF; Schell MJ
    Biometrics; 2005 Jun; 61(2):540-5. PubMed ID: 16011702
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Optimal and minimax three-stage designs for phase II oncology clinical trials.
    Chen K; Shan M
    Contemp Clin Trials; 2008 Jan; 29(1):32-41. PubMed ID: 17544337
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An extension of the single threshold design for monitoring efficacy and safety in phase II clinical trials.
    Brutti P; Gubbiotti S; Sambucini V
    Stat Med; 2011 Jun; 30(14):1648-64. PubMed ID: 21520453
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting population entering phase III trials: a new stratified adaptive phase II design.
    Tournoux-Facon C; De Rycke Y; Tubert-Bitter P
    Stat Med; 2011 Apr; 30(8):801-11. PubMed ID: 21432875
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Toxicity-evaluation designs for phase I/II cancer immunotherapy trials.
    Messer K; Natarajan L; Ball ED; Lane TA
    Stat Med; 2010 Mar; 29(7-8):712-20. PubMed ID: 20213706
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Flexible bivariate phase II clinical trial design incorporating toxicity and response on different schedules.
    Ray HE; Rai SN
    Stat Med; 2013 Feb; 32(3):470-85. PubMed ID: 23147373
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Optimal two-stage designs allowing flexibility in number of subjects for phase II clinical trials.
    Masaki N; Koyama T; Yoshimura I; Hamada C
    J Biopharm Stat; 2009 Jul; 19(4):721-31. PubMed ID: 20183436
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alternative designs of phase II trials considering response and toxicity.
    Jin H
    Contemp Clin Trials; 2007 Jul; 28(4):525-31. PubMed ID: 17428744
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Incorporating toxicity considerations into the design of two-stage phase II clinical trials.
    Bryant J; Day R
    Biometrics; 1995 Dec; 51(4):1372-83. PubMed ID: 8589229
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An adjustment for patient heterogeneity in the design of two-stage phase II trials.
    Sposto R; Gaynon PS
    Stat Med; 2009 Sep; 28(20):2566-79. PubMed ID: 19521973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Adaptive dose selection using efficacy-toxicity trade-offs: illustrations and practical considerations.
    Thall PF; Cook JD; Estey EH
    J Biopharm Stat; 2006; 16(5):623-38. PubMed ID: 17037262
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Methods of joint evaluation of efficacy and toxicity in phase II clinical trials.
    Tournoux C; De Rycke Y; Médioni J; Asselain B
    Contemp Clin Trials; 2007 Jul; 28(4):514-24. PubMed ID: 17331808
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of a misspecification of response rates on type I and type II errors, in a phase II Simon design.
    Baey C; Le Deley MC
    Eur J Cancer; 2011 Jul; 47(11):1647-52. PubMed ID: 21493059
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Optimal continuous sequential boundaries for monitoring toxicity in clinical trials: a restricted search algorithm.
    Goldman AI; Hannan PJ
    Stat Med; 2001 Jun; 20(11):1575-89. PubMed ID: 11391689
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phase I (or phase II) dose-ranging clinical trials: proposal of a two-stage Bayesian design.
    Zohar S; Chevret S
    J Biopharm Stat; 2003 Feb; 13(1):87-101. PubMed ID: 12635905
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Seamless Phase II/III combination study through response adaptive randomization.
    Wang L; Cui L
    J Biopharm Stat; 2007; 17(6):1177-87. PubMed ID: 18027224
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A parallel phase I/II clinical trial design for combination therapies.
    Huang X; Biswas S; Oki Y; Issa JP; Berry DA
    Biometrics; 2007 Jun; 63(2):429-36. PubMed ID: 17688495
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.