184 related articles for article (PubMed ID: 21268072)
1. Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP.
Wang J; Zhao Q; Qi Q; Gu HY; Rong JJ; Mu R; Zou MJ; Tao L; You QD; Guo QL
J Cell Biochem; 2011 Feb; 112(2):509-19. PubMed ID: 21268072
[TBL] [Abstract][Full Text] [Related]
2. CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha.
Fan M; Park A; Nephew KP
Mol Endocrinol; 2005 Dec; 19(12):2901-14. PubMed ID: 16037132
[TBL] [Abstract][Full Text] [Related]
3. CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism.
Kumar P; Ambasta RK; Veereshwarayya V; Rosen KM; Kosik KS; Band H; Mestril R; Patterson C; Querfurth HW
Hum Mol Genet; 2007 Apr; 16(7):848-64. PubMed ID: 17317785
[TBL] [Abstract][Full Text] [Related]
4. Gambogic acid down-regulates MDM2 oncogene and induces p21(Waf1/CIP1) expression independent of p53.
Rong JJ; Hu R; Qi Q; Gu HY; Zhao Q; Wang J; Mu R; You QD; Guo QL
Cancer Lett; 2009 Oct; 284(1):102-12. PubMed ID: 19428175
[TBL] [Abstract][Full Text] [Related]
5. Geldanamycin-induced degradation of Chk1 is mediated by proteasome.
Nomura M; Nomura N; Yamashita J
Biochem Biophys Res Commun; 2005 Sep; 335(3):900-5. PubMed ID: 16099423
[TBL] [Abstract][Full Text] [Related]
6. p53 Stabilization and accumulation induced by human vaccinia-related kinase 1.
Vega FM; Sevilla A; Lazo PA
Mol Cell Biol; 2004 Dec; 24(23):10366-80. PubMed ID: 15542844
[TBL] [Abstract][Full Text] [Related]
7. Targeting the ubiquitin-proteasome system to activate wild-type p53 for cancer therapy.
Allende-Vega N; Saville MK
Semin Cancer Biol; 2010 Feb; 20(1):29-39. PubMed ID: 19897040
[TBL] [Abstract][Full Text] [Related]
8. RNF125 is a ubiquitin-protein ligase that promotes p53 degradation.
Yang L; Zhou B; Li X; Lu Z; Li W; Huo X; Miao Z
Cell Physiol Biochem; 2015; 35(1):237-45. PubMed ID: 25591766
[TBL] [Abstract][Full Text] [Related]
9. SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis.
Li D; Marchenko ND; Moll UM
Cell Death Differ; 2011 Dec; 18(12):1904-13. PubMed ID: 21637290
[TBL] [Abstract][Full Text] [Related]
10. The chaperone-associated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation.
Esser C; Scheffner M; Höhfeld J
J Biol Chem; 2005 Jul; 280(29):27443-8. PubMed ID: 15911628
[TBL] [Abstract][Full Text] [Related]
11. Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells.
Gu H; Wang X; Rao S; Wang J; Zhao J; Ren FL; Mu R; Yang Y; Qi Q; Liu W; Lu N; Ling H; You Q; Guo Q
Mol Cancer Ther; 2008 Oct; 7(10):3298-305. PubMed ID: 18852133
[TBL] [Abstract][Full Text] [Related]
12. Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway.
Rong JJ; Hu R; Song XM; Ha J; Lu N; Qi Q; Tao L; You QD; Guo QL
Cancer Lett; 2010 Oct; 296(1):55-64. PubMed ID: 20413215
[TBL] [Abstract][Full Text] [Related]
13. Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis.
Wang YL; Wu W; Su YN; Ai ZP; Mou HC; Wan LS; Luo Y; Qiu MH; Zhang JH
Phytomedicine; 2020 Mar; 68():153187. PubMed ID: 32097779
[TBL] [Abstract][Full Text] [Related]
14. Arsenic trioxide reactivates proteasome-dependent degradation of mutant p53 protein in cancer cells in part via enhanced expression of Pirh2 E3 ligase.
Yan W; Jung YS; Zhang Y; Chen X
PLoS One; 2014; 9(8):e103497. PubMed ID: 25116336
[TBL] [Abstract][Full Text] [Related]
15. CHIP chaperones wild type p53 tumor suppressor protein.
Tripathi V; Ali A; Bhat R; Pati U
J Biol Chem; 2007 Sep; 282(39):28441-28454. PubMed ID: 17666403
[TBL] [Abstract][Full Text] [Related]
16. Gambogic Acid Induces Cell Apoptosis and Inhibits MAPK Pathway in PTEN
Pan H; Lu LY; Wang XQ; Li BX; Kelly K; Lin HS
Chin J Integr Med; 2018 Feb; 24(2):109-116. PubMed ID: 28578487
[TBL] [Abstract][Full Text] [Related]
17. Chaperone-dependent stabilization and degradation of p53 mutants.
Muller P; Hrstka R; Coomber D; Lane DP; Vojtesek B
Oncogene; 2008 May; 27(24):3371-83. PubMed ID: 18223694
[TBL] [Abstract][Full Text] [Related]
18. Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance.
Kulikov R; Boehme KA; Blattner C
Mol Cell Biol; 2005 Aug; 25(16):7170-80. PubMed ID: 16055726
[TBL] [Abstract][Full Text] [Related]
19. Gambogic acid counteracts mutant p53 stability by inducing autophagy.
Foggetti G; Ottaggio L; Russo D; Monti P; Degan P; Fronza G; Menichini P
Biochim Biophys Acta Mol Cell Res; 2017 Feb; 1864(2):382-392. PubMed ID: 27899303
[TBL] [Abstract][Full Text] [Related]
20. Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells.
Li D; Marchenko ND; Schulz R; Fischer V; Velasco-Hernandez T; Talos F; Moll UM
Mol Cancer Res; 2011 May; 9(5):577-88. PubMed ID: 21478269
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
