BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 21274846)

  • 1. Hydrogel embedding of precision-cut liver slices in a microfluidic device improves drug metabolic activity.
    van Midwoud PM; Merema MT; Verweij N; Groothuis GM; Verpoorte E
    Biotechnol Bioeng; 2011 Jun; 108(6):1404-12. PubMed ID: 21274846
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices.
    van Midwoud PM; Merema MT; Verpoorte E; Groothuis GM
    Lab Chip; 2010 Oct; 10(20):2778-86. PubMed ID: 20835427
    [TBL] [Abstract][Full Text] [Related]  

  • 3. On-line HPLC analysis system for metabolism and inhibition studies in precision-cut liver slices.
    van Midwoud PM; Janssen J; Merema MT; de Graaf IA; Groothuis GM; Verpoorte E
    Anal Chem; 2011 Jan; 83(1):84-91. PubMed ID: 21128611
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Microfluidic biochip for the perifusion of precision-cut rat liver slices for metabolism and toxicology studies.
    van Midwoud PM; Groothuis GM; Merema MT; Verpoorte E
    Biotechnol Bioeng; 2010 Jan; 105(1):184-94. PubMed ID: 19718695
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of a simple incubation system for metabolism studies with precision-cut liver slices.
    Dogterom P
    Drug Metab Dispos; 1993; 21(4):699-704. PubMed ID: 8104130
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Establishment of rat precision-cut fibrotic liver slice technique and its application in verapamil metabolism.
    Guo Y; Wang H; Zhang C
    Clin Exp Pharmacol Physiol; 2007; 34(5-6):406-13. PubMed ID: 17439408
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of apoptotic signaling pathway in metabolic disturbances occurring in liver tissue after cryopreservation: Study on rat precision-cut liver slices.
    Vanhulle VP; Neyrinck AM; Pycke JM; Horsmans Y; Delzenne NM
    Life Sci; 2006 Feb; 78(14):1570-7. PubMed ID: 16236333
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional integrity of precision-cut liver slices from deer and cattle.
    Sivapathasundaram S; Howells LC; Sauer MJ; Ioannides C
    J Vet Pharmacol Ther; 2004 Apr; 27(2):79-84. PubMed ID: 15096104
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Innovative methods to study human intestinal drug metabolism in vitro: precision-cut slices compared with ussing chamber preparations.
    van de Kerkhof EG; Ungell AL; Sjöberg AK; de Jager MH; Hilgendorf C; de Graaf IA; Groothuis GM
    Drug Metab Dispos; 2006 Nov; 34(11):1893-902. PubMed ID: 16914511
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolism of coumarin and 7-ethoxycoumarin by rat, mouse, guinea pig, cynomolgus monkey and human precision-cut liver slices.
    Steensma A; Beamand JA; Walters DG; Price RJ; Lake BG
    Xenobiotica; 1994 Sep; 24(9):893-907. PubMed ID: 7810171
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Short-term maintenance of phase I and II metabolism in precision-cut liver slices in dynamic organ culture.
    Ekins S
    Drug Metab Dispos; 1996 Mar; 24(3):364-6. PubMed ID: 8820429
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Xenobiotic metabolism in rat, dog, and human precision-cut liver slices, freshly isolated hepatocytes, and vitrified precision-cut liver slices.
    Ekins S; Williams JA; Murray GI; Burke MD; Marchant NC; Engeset J; Hawksworth GM
    Drug Metab Dispos; 1996 Sep; 24(9):990-5. PubMed ID: 8886609
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insight into the involvement of Kupffer cell-derived mediators in the hepatoprotective effect of glycine upon inflammation: study on rat precision-cut liver slices.
    Neyrinck AM; Margagliotti S; Delzenne NM
    Inflamm Res; 2005 Mar; 54(3):106-12. PubMed ID: 15883743
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histomorphological changes and cytochrome P450 isoforms expression and activities in precision-cut liver slices from neonatal rats.
    Lupp A; Danz M; Müller D
    Toxicology; 2005 Jan; 206(3):427-38. PubMed ID: 15588932
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Application of precision-cut liver slice to the study of the effect of glutathione on cadmium chloride hepatotoxicity].
    Yang Z; Peng R; Xi J; Wu J
    Wei Sheng Yan Jiu; 2003 Sep; 32(5):429-31. PubMed ID: 14650181
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Increased post-thaw viability and phase I and II biotransformation activity in cryopreserved rat liver slices after improvement of a fast-freezing method.
    de Graaf IA; van der Voort D; Brits JH; Koster HJ
    Drug Metab Dispos; 2000 Sep; 28(9):1100-6. PubMed ID: 10950856
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A species comparison of 14C-labeled 7-ethoxycoumarin metabolism in precision-cut liver slices from guinea pig and dog using a phosphor imaging system.
    Terada T; Kaneko H; Terashita S; Tozuka Z; Tokuma Y; Hata T
    Res Commun Mol Pathol Pharmacol; 1996 Jan; 91(1):41-56. PubMed ID: 8824930
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Coordinated induction of drug transporters and phase I and II metabolism in human liver slices.
    Olinga P; Elferink MG; Draaisma AL; Merema MT; Castell JV; Pérez G; Groothuis GM
    Eur J Pharm Sci; 2008 Apr; 33(4-5):380-9. PubMed ID: 18328680
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Toxicity of atractyloside in precision-cut rat and porcine renal and hepatic tissue slices.
    Obatomi DK; Brant S; Anthonypillai V; Bach PH
    Toxicol Appl Pharmacol; 1998 Jan; 148(1):35-45. PubMed ID: 9465261
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative cytotoxicity of N-substituted N'-(4-imidazole-ethyl)thiourea in precision-cut rat liver slices.
    Onderwater RC; Commandeur JN; Vermeulen NP
    Toxicology; 2004 Apr; 197(2):81-91. PubMed ID: 15003319
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.